Novel Insights Into The Molecular Diagnosis And Therapy Of Pancreatic Cancer
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Molecular Diagnostics and Treatment of Pancreatic Cancer
| Author | : Asfar Azmi |
| Publisher | : Elsevier |
| Total Pages | : 467 |
| Release | : 2014-04-14 |
| Genre | : Medical |
| ISBN | : 0124079466 |
Molecular Diagnostics and Treatment of Pancreatic Cancer describes the different emerging applications of systems biology and how it is shaping modern pancreatic cancer research. This book begins by introducing the current state of the art knowledge, trends in diagnostics, progress in disease model systems as well as new treatment and palliative care strategies in pancreatic cancer. Specific sections are dedicated to enlighten the readers to newer discoveries that have emerged from gene expression profiling, proteomics, metabolomics and systems level analyses of pancreatic cancer datasets. First of a kind and novel network strategies to understand oncogenic Kras signaling in pancreatic tumors are presented. The attempts to computationally model and prioritize microRNAs that cause pancreatic cancer resistance are also highlighted. Addressing this important area, Molecular Diagnostics and Treatment of Pancreatic Cancer provides insights into important network evaluation methodologies related to pancreatic cancer related microRNAs targetome. There are dedicated chapters on critical aspects of the evolving yet controversial field of pancreatic cancer stems cells. The work concludes by discussing the applications of network sciences in pancreatic cancer drug discovery and clinical trial design. Encompasses discussion of innovative tools including expression signatures in cell lines, 3D models, animal xenograft models, primary models and patient derived samples, aiding subversion of traditional biology paradigms, and enhancing comprehension across conventional length and temporal scales Coverage includes novel applications in targeted drugs, polypharmacology, network pharmacology and other related drug development arenas – helping researchers in pancreatic cancer drug discovery Summarizes many relevant computational and clinical references from fast-evolving literature Comprehensive glossary helps newer readers understand technical terms and specialized nomenclature
Pancreatic Cancer
| Author | : Howard Reber |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 553 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 1461218101 |
A distinguished panel of world authorities reviews the current state of today's understanding, diagnosis, and treatment of pancreatic cancer. Their cutting-edge reviews discuss both medical and surgical modalities and include numerous insights into the basic molecular processes underlying the disease. Among the key topics covered are the prospects for early diagnosis using molecular techniques, the latest diagnostic and therapeutic methods, the role of laparoscopy (diagnostic and therapeutic), and nonsurgical treatment. The reviewers also address the future possibilities for clinical advances, quality of life concerns, and the value of the Japanese "extended Whipple resection." Pancreatic Cancer will become the new standard reference for all clinicians who diagnose and treat this disease, as well as for basic scientists needing a summary of the many recent advances. i
Complete Guide to Pancreatic Cancer
| Author | : Dehart Hairston |
| Publisher | : Independently Published |
| Total Pages | : 0 |
| Release | : 2024-06 |
| Genre | : Science |
| ISBN | : |
Unlock the comprehensive knowledge you need to navigate the complexities of pancreatic cancer with the authoritative "Complete Guide to Pancreatic Cancer. This groundbreaking book offers a thorough exploration of every facet of pancreatic cancer, from its etiology to advanced treatment modalities. Delve into the intricate mechanisms underlying pancreatic cancer development, including genetic predispositions, environmental factors, and emerging biomarkers. Gain invaluable insights into the latest diagnostic techniques, including imaging modalities such as CT scans, MRI, and endoscopic ultrasound, as well as cutting-edge molecular diagnostic tools. Explore the diverse array of treatment options available for pancreatic cancer patients, including surgery, chemotherapy, radiation therapy, targeted therapies, and immunotherapy. Learn how to tailor treatment strategies based on individual patient characteristics, tumor biology, and disease stage, optimizing outcomes and enhancing quality of life. Navigate the complexities of managing treatment-related side effects and complications with expert guidance on symptom management, nutritional support, pain control, and psychosocial care. Gain a deeper understanding of the multidisciplinary approach to pancreatic cancer care, encompassing collaboration among oncologists, surgeons, gastroenterologists, radiologists, pathologists, and allied health professionals. Stay abreast of the latest breakthroughs in pancreatic cancer research, from novel therapeutic targets and drug developments to promising clinical trials and personalized medicine approaches. Benefit from practical tips and strategies for patient advocacy, survivorship, and end-of-life care, empowering patients and their families to make informed decisions throughout their cancer journey. Written in a clear, accessible manner and supplemented with illustrative case studies, clinical pearls, and evidence-based recommendations, the "Complete Guide to Pancreatic Cancer" is an indispensable resource for oncologists, healthcare professionals, researchers, patients, and caregivers alike. Whether you are seeking to deepen your understanding of pancreatic cancer or striving to optimize patient care, this comprehensive guide is your essential companion in the fight against this challenging disease.
Theranostic Approach for Pancreatic Cancer
| Author | : Ganji Purnachandra Nagaraju |
| Publisher | : Academic Press |
| Total Pages | : 420 |
| Release | : 2020-01-15 |
| Genre | : |
| ISBN | : 9780128194577 |
Theranostic Approach for Pancreatic Cancer modulates the biologic properties of stroma in pancreatic cancer by targeting the several chemotherapy resistance mechanisms to impede their malignant property through introducing new strategies and drugs for tackling the disease. It brings information about ongoing research as well as clinical data about pancreatic cancer and provides detailed descriptions about diagnostic and therapeutic options for easy understanding. This book discusses several topics related to pancreatic cancer such as stem cells, drug resistance and pancreatic tumor microenvironment, the latest developments in chemotherapy for metastatic cancer and chemoprevention, and epigenome as a therapeutic strategy. Additionally, it encompasses a discussion on theranostic clinical applications for personalized treatment and management of pancreatic cancer. The book is a valuable resource for cancer researchers, oncologists, and several members of the biomedical field who need to understand more about the diagnosis and treatment of pancreatic cancer. Provides information on the roadblocks of chemotherapy in patients with newly diagnosed and metastatic pancreatic cancer Discusses treatment options available currently as well as prospective options for the future Focuses especially on stroma, tumor microenvironment, stem cells, stellate cells, transcription factors, growth factors, and important signaling pathways as already tested types of treatment
The Quantum Code of Pancreatic Neuroendocrine Tumors
| Author | : Volker Fendrich |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2024-08-07 |
| Genre | : Medical |
| ISBN | : 9781022898202 |
Dive into 'The Quantum Code of Pancreatic Neuroendocrine Tumors: Insights from Recent Studies, ' a meticulously curated collection of scientific journal articles that unveils the intricate world of Pancreatic Neuroendocrine Tumors (PanNETs). This comprehensive anthology brings forth pioneering research and clinical insights into the complexities of PanNETs, which, despite being a small percentage of pancreatic cancers, pose significant diagnostic and therapeutic challenges. Covering a spectrum of themes-from novel genetic analyses and innovative therapeutic approaches to the role of biomarkers in early diagnosis-the articles present robust data from clinical trials, preclinical drug efficacy, and the application of machine learning algorithms in radiomics for diagnostic precision. Readers will gain a detailed understanding of topics such as the impact of drugs like Sorafenib, genetic and molecular signatures, and comparative studies of treatments like everolimus and sunitinib. The focus on emerging biomarkers like miRNAs and proteins such as UCH-L1 and ?-internexin promises a transformative approach in precision medicine, enhancing patient stratification, and personalized therapies. The book is an essential read for oncologists, radiologists, endocrinologists, and researchers keen on exploring interdisciplinary strategies for better management of PanNETs, emphasizing the integration of scientific rigor and clinical relevance to improve patient outcomes. Quality Research Publishing is dedicated to making knowledge more accessible to the general public by curating a topical compilation of the latest research on various subjects and providing plain language summaries. Each of the articles in this book is available individually and digitally without cost. However, we believe it is important for the contextualizing and sharing of educational and scientific work to curate this research in a way that is understandable and helpful to the average person seeking deeper knowledge of a particular subject. The research articles compiled for this book were published under a permissive Creative Commons license, are in the public domain, or have no copyright restrictions, permitting their use in this book. If you have questions about the licensing of any article, please visit qualityresearchpublishing.com.
Pancreatic Cancer
| Author | : Born Incredible |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2024-01-29 |
| Genre | : Health & Fitness |
| ISBN | : |
"Pancreatic Cancer: A Comprehensive Resource for Patients and Families" is an essential guide for anyone affected by this challenging disease. This meticulously crafted book offers an in-depth look into the world of pancreatic cancer, providing valuable insights and support for patients, their families, and caregivers. Structured into a number of thoughtfully organized chapters, this book covers a wide range of critical topics: Begin your journey with an understanding of Pancreatic Cancer, exploring its biology, types, and the risk factors involved. Learn about Symptoms and Early Detection to recognize signs and the importance of timely diagnosis. The Diagnosis of Pancreatic Cancer chapter navigates through the complex processes of imaging, biopsies, and the significance of staging. Delve into Treatment Options, discussing the nuances of surgery, radiation, chemotherapy, and newer therapies like immunotherapy. Managing Side Effects and Complications offers practical advice on dealing with treatment's physical and emotional impacts. Advanced and Metastatic Pancreatic Cancer addresses the challenges of more severe cases and focuses on palliative care. Stay informed about the latest advancements with a chapter on Clinical Trials and Research. The Role of Genetics in pancreatic cancer is demystified, providing insights into familial risks and genetic testing. Emphasize Prevention and healthy living through chapters on Lifestyle and Prevention. Find solace and support with our comprehensive guide on Support for Patients and Families, discussing emotional coping strategies and caregiver roles. Navigate the often-overlooked Legal and Financial Issues that arise with long-term illness. End-of-Life Care provides sensitive and practical advice for making difficult decisions. Survivors and Life After Treatment focuses on the challenges and triumphs post-treatment. Finally, look towards the Future of Pancreatic Cancer Treatment, exploring emerging therapies and the promise of personalized medicine. "Packed with information and practical advice, 'Pancreatic Cancer: A Comprehensive Resource for Patients and Families' is more than just a book; it's a companion in your journey, offering hope, understanding, and guidance through every stage of this illness. This book is an invaluable tool for anyone touched by pancreatic cancer, whether you are a patient, a loved one, or a medical professional seeking to provide the best care and support."
Essential Concepts in Molecular Pathology
| Author | : William B. Coleman |
| Publisher | : Academic Press |
| Total Pages | : 634 |
| Release | : 2019-11-23 |
| Genre | : Medical |
| ISBN | : 0128132582 |
Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today’s advances in pathology and medicine. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology
