Handbook of Retinal Disease: a Case-based Approach

Handbook of Retinal Disease: a Case-based Approach
Author: Elias Reichel
Publisher: JP Medical Ltd
Total Pages: 348
Release: 2015-02-15
Genre: Medical
ISBN: 1907816925

Handbook of Retinal Disease offers the benefit of a case discussion by describing retinal disorders through real-life examples.The book features over 75 cases with high quality images and a highly structured, deductive approach.This book is the most clinically relevant guide possible to the latest imaging techniques used in the diagnosis of retinal diseases.

Retinal Degenerations

Retinal Degenerations
Author: Joyce Tombran-Tink
Publisher: Springer Science & Business Media
Total Pages: 465
Release: 2007-11-06
Genre: Medical
ISBN: 159745186X

This book presents new and noteworthy research into retinal diseases. It focuses on what we currently know about the environment, genetics and mechanisms that lead to retinal degenerations, new diagnostics, and innovative therapeutic modalities to preserve vision. Written by renowned scientific investigators, this innovative collection of treatment strategies and technological discoveries allows for the realistic translation of research into practice.

Retinal Degenerative Diseases

Retinal Degenerative Diseases
Author: Professor of Laboratory Medicine and Pathology and Therapeudic Radiology-Radiation Oncology Robert E Anderson
Publisher: Springer
Total Pages: 764
Release: 2016-05-01
Genre:
ISBN: 9781493950867

TheInternationalSymposiumonRetinalDegenerationhasbeenheldinconjunction withthebiennialInternationalCongressofEyeResearch(ICER)since1984. These RDSymposiahaveallowedbasicandclinicianscientistsfromaroundtheworldto conveneandpresenttheirnewresearch?ndings. Theyhavebeenorganizedtoallow suf?cienttimefordiscussionsandone-on-oneinteractionsinarelaxedatmosphere, whereinternationalfriendshipsandcollaborationscanbefostered. The XIII International Symposium on Retinal Degeneration (also known as RD2008) was held from September 18-23, 2008 at the Hong Zhu Shan Hotel at thefootofEmeiMountainintheSichuanProvinceofChina, nearChengdu. The meeting brought together 152 basic and clinician scientists, retinal specialists in ophthalmology, andtraineesinthe?eldfromallpartsoftheworld. Inthecourse ofthemeeting,42platformand88posterpresentationsweregiven, andamajority ofthesearepresentedinthisproceedingsvolume. Newdiscoveriesandstateofthe art?ndingsfrommostresearchareasinthe?eldofretinaldegenerationswerep- sented. TheRD2008meetingwashighlightedbythreespeciallectures. The?rstwas givenby Glen Prusky, PhD, WeillCornellMedicalCollegeofCornellUniversity, New York City, NY. Dr. Prusky discussed the measures of vision in rodents as a tool for evaluating the treatment of retinal degenerative diseases. The second was given by Kang Zhang, MD, PhD, on the molecular genetics of Stargardt's Disease. Dr. Zhang's undergraduate degree in biochemistry is from West China University in Chengdu, and he currently is at the Shiley Eye Center, University ofCaliforniaatSanDiego, SanDiego, CA. Thethirdplenarylecturewasgivenby Peter Campochiaro, MD, oftheWilmerEyeInstitute, JohnsHopkinsUniversity, Baltimore, MD. Dr. Campochiaro discussed the role of oxidant stress in macular degeneration. This Symposium would not have been possible without the support of our colleagues at the Sichuan People's Provincial Hospital and the Department of Ophthalmology of West China Hospital, Sichuan University. Fan Ying Chuan, MD, ViceChairman, SichuanOphthalmologySociety, DirectorofOphthalmology Department, SichuanAcademyofMedicalScience&SichuanProvincialPeople's Hospitaland Chen Xiao Ming, MD, Chairman, SichuanOphthalmologySociety, Director of West China Eye Center, West China Hospital, Sichuan University, gave tirelessly to our effort from the beginning. We are especially grateful to the ix x Preface administration of the Sichuan People's Provincial Hospital, which provided the ?nancialguaranteesnecessarytosecurethemeetingvenue. Theassistanceof Chen Hui (Robert), MD, of the SPPH throughout the planning and the meeting itself were of enormous help to us.

Practical Atlas of Retinal Disease and Therapy

Practical Atlas of Retinal Disease and Therapy
Author: William R. Freeman
Publisher: Lippincott Williams & Wilkins
Total Pages: 424
Release: 1997
Genre: Medical
ISBN:

Now in its revised, updated Second Edition, this unique atlas is a practical, well-organized, and thoroughly illustrated guide to the diagnosis and treatment of retinal diseases. The book combines succinct, pragmatic discussions of diagnostic and therapeutic strategies with more than 700 full-color retinal photographs, which clearly and vividly depict the distinguishing features of each disease and the most effective treatment techniques. The photographs and text will enable clinicians to rapidly diagnose specific disease entities and determine the most appropriate medical or surgical therapy. The Second Edition features four new chapters on endophthalmitis; submacular surgery; arterial and related retinovascular occlusive disease; and macular holes and other surgical macular disorders. Numerous new illustrations have been added, and many illustrations from the previous edition have been replaced by new ones of greater clarity. Chapters have been updated to provide state-of-the-art information on current diagnostic and therapeutic modalities.

Molecular Therapies for Inherited Retinal Diseases

Molecular Therapies for Inherited Retinal Diseases
Author: Rob W J Collin
Publisher:
Total Pages: 262
Release: 2020-10-07
Genre:
ISBN: 9783039431762

Following the implementation of next-generation sequencing technologies (e.g., exome and genome sequencing) in molecular diagnostics, the majority of genetic defects underlying inherited retinal disease (IRD) can readily be identified. In parallel, opportunities to counteract the molecular consequences of these defects are rapidly emerging, providing hope for personalized medicine. 'Classical' gene augmentation therapy has been under study for several genetic subtypes of IRD and can be considered a safe and sometimes effective therapeutic strategy. The recent market approval of the first retinal gene augmentation therapy product (LuxturnaTM, for individuals with bi-allelic RPE65 mutations) by the FDA has not only demonstrated the potential of this specific approach, but also opened avenues for the development of other strategies. However, every gene-or even every mutation-may need a tailor-made therapeutic approach, in order to obtain the most efficacious strategy with minimal risks associated. In addition to gene augmentation therapy, other subtypes of molecular therapy are currently being designed and/or implemented, including splice modulation, DNA or RNA editing, optogenetics and pharmacological modulation. In addition, the development of proper delivery vectors has gained strong attention, and should not be overlooked when designing and testing a novel therapeutic approach. In this Special Issue, we aim to describe the current state of the art of molecular therapeutics for IRD, and discuss existing and novel therapeutic strategies, from idea to implementation, and from bench to bedside.

High Resolution Imaging in Microscopy and Ophthalmology

High Resolution Imaging in Microscopy and Ophthalmology
Author: Josef F. Bille
Publisher: Springer
Total Pages: 411
Release: 2019-08-13
Genre: Medical
ISBN: 3030166384

This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.

Retinal Degenerative Diseases

Retinal Degenerative Diseases
Author: Matthew M. LaVail
Publisher: Springer Science & Business Media
Total Pages: 867
Release: 2011-12-21
Genre: Medical
ISBN: 1461406315

This book will contain the proceedings of the XIV International Symposium on Retinal Degeneration (RD2010), held July 13-17, 2010, in Mont-Tremblant, Quebec, Canada. The volume will present representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; candidate genes, cloning, mapping and other aspects of molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy.