Non-CML Myeloproliferative Diseases, An Issue of Hematology/Oncology Clinics of North America

Non-CML Myeloproliferative Diseases, An Issue of Hematology/Oncology Clinics of North America
Author: Ross Levine
Publisher: Elsevier Health Sciences
Total Pages: 193
Release: 2012-10-28
Genre: Medical
ISBN: 1455747645

Topics include: Clinical Predictors of Outcome in MPNs; Molecular pathogenesis of MPNs; Disordered signaling in MPNs; Role of TET2/ASXL1 in MPN Pathogenesis; Pathogenesis and treatment of systemic mastocytosis; Role of additional novel therapies in MPNs; Role of novel mutations in MPN pathogenesis and outcome; Role of JAK inhibitors in MPN treatment; Animal Models of MPNs; and Role of Germline Genetic Factors in MPN Pathogenesis.

Chronic Lymphocytic Leukemia, An Issue of Hematology/Oncology Clinics of North America

Chronic Lymphocytic Leukemia, An Issue of Hematology/Oncology Clinics of North America
Author: Jennifer R. Brown
Publisher: Elsevier Health Sciences
Total Pages: 301
Release: 2013-04-28
Genre: Medical
ISBN: 1455771880

This issue of Hematology/Oncology Clinics is edited by Dr. Jennifer Brown and focuses on Chronic Lymphocytic Leukemia. Article topics include: What Have Recent Genomic Advances Taught us About CLL?, Biology of CLL in Different Microenvironments,What is the Significance of Stereotyped BCRs in CLL?, Understanding Immunodeficiency in CLL, MBL vs CLL: How Important is the Distinction?, Risk Stratification of CLL in 2012, Minimal Residual Disease Measurement in CLL, The BTK Inhibitor PCI-32765 in CLL, and Evolving Role of Stem Cell Transplantation in CLL.

Consultative Hematology, An Issue of Hematology/Oncology Clinics of North America

Consultative Hematology, An Issue of Hematology/Oncology Clinics of North America
Author: Fred J. Schiffman
Publisher: Elsevier Health Sciences
Total Pages: 256
Release: 2012-04-28
Genre: Medical
ISBN: 1455744077

Topics include: Why does my patient have leukocytosis?, Why Is My Patient Neutropenic?, Does My Patient with a Serum Monoclonal Spike have Multiple Myeloma?, DVT and Pulmonary Embolism, Why Does My Patient Have Lymphadenopathy/Splenomegaly?,and Why Does My Patient have Thrombocytopenia?

Neutropenia, An Issue of Hematology/Oncology Clinics of North America

Neutropenia, An Issue of Hematology/Oncology Clinics of North America
Author: Christoph Klein
Publisher: Elsevier Health Sciences
Total Pages: 272
Release: 2013-02-28
Genre: Medical
ISBN: 1455771872

This issue of Hematology/Oncology Clinics is guest edited by Dr. Christoph Klein and focuses on the topic of Neutropenia. Article titles include: Homeostasis and migration of neutrophil granulocytes,Granulocyte-colony Stimulating Factor (G-CSF) receptor signaling,New Granulocyte-colony Stimulating Factor (G-CSF) Receptor Signaling Pathways ,Neutrophil elastase (ELANE) – Genetics and Pathophysiology,Autosomal recessive variants of Severe congenital neutropenia (SCN),Leukocyte Adhesion Deficiency (LAD), and Genotype-phenotype correlations in Severe congenital neutropenia (SCN).

Central Nervous System Malignancies, An Issue of Hematology/Oncology Clinics of North America

Central Nervous System Malignancies, An Issue of Hematology/Oncology Clinics of North America
Author: Jill Lacy
Publisher: Elsevier Health Sciences
Total Pages: 260
Release: 2012-08-28
Genre: Medical
ISBN: 1455747637

Topics include: Neoplastic Meningitis and Epidural Metastases: Evaluation and Management; Management of Brain Metastases: Surgery, Radiation, or Both?; Meningiomas/Nerve Sheath Tumors/Pituitary Tumors: Diagnosis and Treatment; Medulloblastoma/Primitive Neuroectodermal Tumor and Germ Cell Tumors: The Uncommon but Potentially Curable Primary Brain Tumors; Primary CNS Lymphoma: Overview of Current Treatment Strategies; Anaplastic Gliomas: Radiation, Chemotherapy, or Both?; Low Grade Gliomas: When and How to Treat?; Glioblastoma Multiforme: Overview of Current Treatment and Future Perspectives.

Myeloproliferative Neoplasms, An Issue of Hematology/Oncology Clinics of North America

Myeloproliferative Neoplasms, An Issue of Hematology/Oncology Clinics of North America
Author: John Mascarenhas
Publisher: Elsevier Health Sciences
Total Pages: 313
Release: 2021-02-27
Genre: Medical
ISBN: 0323795897

This issue of Hematology/Oncology Clinics, guest edited by Drs. Ronald Hoffman, Ross Levine, John Mascarenhas, and Raajit Rampal, is dedicated to Myeloproliferative Neoplasms. This issue is one of six selected each year by the series consulting editors, Drs. George P. Canellos and Edward J. Benz. Topics in this issue include—but are not limited to— Overview of pathophysiology and potential drug targets, The role of the megakaryocyte, Epigenetics, Genetics, Novel technologies for understanding MPN biology, Important pathology considerations, Current Clinical investigations, Quality of life, Application of stem cell therapy, Immunotherapy approaches, Clinical unmet needs in ET/PV, Accelerated and blast phase MPNs, Epidemiology, Thrombotic and hemorrhagic complications, Murine modeling, The microenvironment in MPNs, MDS/MPN overlap syndrome, and Advancing effective clinical trial designs.

Rare Cancers, An Issue of Hematology/Oncology Clinics of North America

Rare Cancers, An Issue of Hematology/Oncology Clinics of North America
Author: Guy D. Eslick
Publisher: Elsevier Health Sciences
Total Pages: 263
Release: 2012-12-28
Genre: Medical
ISBN: 1455747653

Topics include: Rare Cancers; Mast Cell Leukemia; Uveal Melanoma; Esthesioneuroblastoma; Parathyroid Carcinoma; Thymoma/Thymic Carcinoma; Mesothelioma; Gastrointestinal Stromal Tumor (GIST); Uterine Sarcoma; Cancer of the Appendix; Urethral Cancer; Anal Cancer; and Merkel Cell Carcinoma.

Hematology/Oncology Emergencies, An Issue of Hematology/Oncology Clinics of North America

Hematology/Oncology Emergencies, An Issue of Hematology/Oncology Clinics of North America
Author: John C. Perkins
Publisher: Elsevier Health Sciences
Total Pages:
Release: 2017-11-06
Genre: Medical
ISBN: 0323611486

This issue of Hematology/Oncology Clinics, edited by Drs. John Perkins and and Jonathan Davis, focuses on emergencies related to Hematology/Oncology and covers topics such as: Oncologic Mechanical Emergencies, Neutropenic Fever, Oncologic Metabolic Emergencies, Acute Leukemias, Pediatric Oncologic Emergencies, Chemotherapeutic Medications and their Emergent Complications, Anemia, Thrombotic Microangiopathies (TTP, HUS, HELLP), Congenital Bleeding Disorders, Acquired Bleeding Disorders and Antithrombotic agents, Sickle Cell Disease, and more!

Drug Safety: Managing Innovation in Rheumatology, An Issue of Rheumatic Disease Clinics

Drug Safety: Managing Innovation in Rheumatology, An Issue of Rheumatic Disease Clinics
Author: John J Cush
Publisher: Elsevier Health Sciences
Total Pages: 183
Release: 2012-11-28
Genre: Medical
ISBN: 145575059X

Edited by Drs. Jack Cush and Kathryn Dao, this issue of Rheumatic Disease Clinics of North America addresses one of the most significant issues facing the rheumatologist today––drug safety in a changing world where rheumatoid arthritis (RA) severity is less, patients are being identified and treated at a very early stage, and prevention is on the horizon. Topics covered include: communicating the risk of side effects, urate-lowering therapies, biphosphonates, biologics, malignancy risks, and administering therapies to patients with co-morbidities.