NLRP3 Inflammasome: Regulatory Mechanisms, Role in Health and Disease and Therapeutic Potential
| Author | : Kuo-Feng Hua |
| Publisher | : Frontiers Media SA |
| Total Pages | : 376 |
| Release | : 2021-11-08 |
| Genre | : Medical |
| ISBN | : 2889716023 |
Nlrp3 Inflammasome Regulatory Mechanisms Role In Health And Disease And Therapeutic Potential
Download Nlrp3 Inflammasome Regulatory Mechanisms Role In Health And Disease And Therapeutic Potential full books in PDF, epub, and Kindle. Read online free Nlrp3 Inflammasome Regulatory Mechanisms Role In Health And Disease And Therapeutic Potential ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
The Inflammasome
| Author | : Christine M. De Nardo |
| Publisher | : Humana |
| Total Pages | : 0 |
| Release | : 2013-07-13 |
| Genre | : Medical |
| ISBN | : 9781627035224 |
This Methods in Molecular Biology book offers methods for studying inflammasome function, including generation of inflammasome stimuli, monitoring of caspase-1 activity and processing, activation of IL-1β cytokines, plus lab protocols, material lists and tips.
DNA Sensors and Inflammasomes
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 370 |
| Release | : 2019-08-25 |
| Genre | : Science |
| ISBN | : 0128183608 |
DNA Sensors and Inflammasomes, Volume 625, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. New sections in this release include Phosphorylation and dimerization of STING and IRF3, cGAS enzymology, Synthesis and identification of immuno-stimulatory CDNs, Tracking cGAS activity/ cGAMP formation using SPR/NMR, Using an enzyme coupled assay to track cGAS activity under steady states, Tracking the polymerization of DNA sensors, inflammasome receptors, and downstream signaling partners using FRET, NLRC4 structure, Tracking TREX1 activity, DNA association and dissociation kinetics of PARP1, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Enzymology series - Includes the latest information on DNA sensors and inflammasomes
Free Fatty Acid Receptors
| Author | : Graeme Milligan |
| Publisher | : Springer |
| Total Pages | : 258 |
| Release | : 2017-02-08 |
| Genre | : Medical |
| ISBN | : 3319506935 |
This book highlights the important role free fatty acids (FFA) play as potential drug targets. While FFA have long been considered byproducts of cell metabolism, they are now recognized as ligands that regulate cell and tissue function via G-protein-coupled receptors. At least three receptors have been identified for which FFA appear to be the endogenous ligands.
Autophagy: Biology and Diseases
| Author | : Weidong Le |
| Publisher | : Springer Nature |
| Total Pages | : 734 |
| Release | : 2020-07-15 |
| Genre | : Medical |
| ISBN | : 9811542724 |
This book consists of 3 volumes: Basic Science (Volume 1), Clinical Science (Volume 2) and Technology and Methodology (Volume 3). Volume 2 focuses on the clinical aspects of autophagy research, discussing the role of autophagy in neuropsychiatric disorders, the cardiovascular, immune, digestive and endocrine systems, as well as tumors, infection, the kidney, and the respiratory and hematological systems. It also addresses autophagy-related drug development. Written and edited by a team of 90 experts, and presenting the state of the art in autophagy research, this book is a valuable reference resource for researchers and clinicians alike. It can also be used as supplementary material for graduate students majoring in biology and medicine
Gout & Other Crystal Arthropathies E-Book
| Author | : Robert Terkeltaub |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 374 |
| Release | : 2011-08-19 |
| Genre | : Medical |
| ISBN | : 1455727105 |
Gout and Other Crystal Arthropathies, by Dr. Robert Terkeltaub, presents the state-of-the-art, clinically-focused coverage you need to manage these increasingly prevalent diseases. Diagnose the full range of crystal arthropathies—including pseudogout, intercritical gout, hyperuricemia, and gouty arthritis—and treat your patients effectively with discussions of recently-approved drugs like Uloric and those currently under review, such as Kristexxa and Colcryst. With coverage of the latest therapies, preventions, and imaging studies, along with access to the fully searchable text online at www.expertconsult.com, this comprehensive resource is ideal for any physician who diagnoses, treats, and manages gout and crystal-induced arthropathies. Stay current on recent developments such as uricosuric therapy and inhibitor therapy; gout flare prophylaxis and colchicines; ultrasound in the diagnosis of crystal deposition diseases; imaging of gout, CPPD, and hydroxyapatitie deposition diseases; and uricase therapy of gout. Manage the full range of crystal arthropathies with 25 clinically-focused chapters on pseudogout, intercritical gout, hyperuricemia, gouty arthritis, and more. Treat your patients effectively using the latest information on drug treatments, from the recently-approved Uloric to Kristexx and Colcryst, which are still under review.
Melatonin
| Author | : Andrew Miles |
| Publisher | : Oxford University Press, USA |
| Total Pages | : 312 |
| Release | : 1988 |
| Genre | : Medical |
| ISBN | : |
A review of the areas of clinical medicine where melatonin is thought to play an important role, attempting to clarify the role of melatonin, to suggest avenues for future research, and to provide the first synthesis of basic and clinical research for scientists and those in pineal research.
Anti-Aging Pharmacology
| Author | : Vitaly Koltover |
| Publisher | : Academic Press |
| Total Pages | : 400 |
| Release | : 2022-12-07 |
| Genre | : Medical |
| ISBN | : 0128236809 |
Anti-Aging Pharmacology provides an overview of current research aimed at the pharmacological modulation of aging, including a discussion of the growing number of novel drug classes with promising anti-aging potential. The aging process is the main risk factor for all chronic diseases affecting the elderly. With lifespans extending across the globe, these chronic diseases are placing a larger burden on individuals and health care systems. Therefore, slowing down the aging rate could be more effective in delaying aging-associated chronic disorders than combating them one by one, which is the conventional approach in a current disease-based pharmacological paradigm. This book contains the work of the world's leading researchers in the field, including sections on the conceptual and methodological background of anti-aging pharmacology, the basic classes of anti-aging drugs, phytochemicals, outcomes of anti-aging developments and future directions. This book will be of interest to a wide audience, ranging from pharmacologists, medicinal chemists and academic researchers in gerontology, biomedical sciences and those in medical practice. - Includes updated information about current developments in anti-aging pharmacology - Offers practical advice on the applicability of certain healthspan-promoting medications - Discusses potential challenges related to the translation of anti-aging drugs in clinical practice
Lipid Signaling and Metabolism
| Author | : James M. Ntambi |
| Publisher | : Academic Press |
| Total Pages | : 570 |
| Release | : 2020-08-09 |
| Genre | : Science |
| ISBN | : 0128194057 |
Lipid Signaling and Metabolism provides foundational knowledge and methods to examine lipid metabolism and bioactive lipid signaling mediators that regulate a broad spectrum of biological processes and disease states. Here, world-renowned investigators offer a basic examination of general lipid, metabolism, intracellular lipid storage and utilization that is followed by an in-depth discussion of lipid signaling and metabolism across disease areas, including obesity, diabetes, fatty liver disease, inflammation, cancer, cardiovascular disease and mood-related disorders. Throughout, authors demonstrate how expanding our understanding of lipid mediators in metabolism and signaling enables opportunities for novel therapeutics. Emphasis is placed on bioactive lipid metabolism and research that has been impacted by new technologies and their new potential to transform precision medicine. - Provides a clear, up-to-date understanding of lipid signaling and metabolism and the impact of recent technologies critical to advancing new studies - Empowers researchers to examine bioactive lipid signaling and metabolism, supporting translation to clinical care and precision medicine - Discusses the role of lipid signaling and metabolism in obesity, diabetes, fatty liver disease, inflammation, cancer, cardiovascular disease and mood-related disorders, among others
Stress and Inflammation in Disorders
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 0 |
| Release | : 2017-04-17 |
| Genre | : Science |
| ISBN | : 9780128123881 |
Stress and Inflammation in Disorders, Volume 108, the newest volume in this ongoing series, brings forth new information on protocols and analysis of proteins. This volume covers the latest on Oxidative Stress: Love and Hate History in the Central Nervous System, Neuroinflammation in Alzheimer's Disease: The Preventive and Therapeutic Potential of Polyphenolic Nutraceuticals, Inflammation in Epileptic Encephalopathies, A Computational Approach to Identify the Biophysical and Structural Aspect of Methylenetetrahydrofolate Reductase (MTHFR) Mutations (A222V, E429A and R594Q) Leading to Schizophrenia, and Analyzing the Effect of V66M Mutation in BDNF in Causing MOOD Disorders- A Computational Approach. Each release in the Advances in Protein Chemistry and Structural Biology series is an essential resource for protein chemists, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.
