New Weapons To Control Bacterial Growth
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| Author | : Tomas G. Villa |
| Publisher | : Springer |
| Total Pages | : 552 |
| Release | : 2016-03-24 |
| Genre | : Science |
| ISBN | : 3319283685 |
Written by specialists in the different fields, this book presents new perspectives and insights into strategies and weapons to fight microbial infections. It also reviews the “state of the art” of alternative treatment approaches and new therapeutic agents to deal with infections caused by multidrug-resistant microorganisms. In an era of accumulated resistance to current antibiotics, it is vital that this is undertaken without further delay. Aspects discussed include the control of RNA synthesis, the use of bacteriocins or enzybiotics (bacteriophages or purified lysins), the specific control of pathogenic clostridia, the design of new drugs affecting DNA synthesis in bacteria, the use of fecal-matter transplant strategies, the specific control of quorum sensing responses in bacteria, the use of new peptides as antibiotics and new ways to control bacteria that cause cancer, such as Helicobacter pylori cancers.
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 397 |
| Release | : 2003-08-25 |
| Genre | : Medical |
| ISBN | : 0309185548 |
Infectious diseases are a global hazard that puts every nation and every person at risk. The recent SARS outbreak is a prime example. Knowing neither geographic nor political borders, often arriving silently and lethally, microbial pathogens constitute a grave threat to the health of humans. Indeed, a majority of countries recently identified the spread of infectious disease as the greatest global problem they confront. Throughout history, humans have struggled to control both the causes and consequences of infectious diseases and we will continue to do so into the foreseeable future. Following up on a high-profile 1992 report from the Institute of Medicine, Microbial Threats to Health examines the current state of knowledge and policy pertaining to emerging and re-emerging infectious diseases from around the globe. It examines the spectrum of microbial threats, factors in disease emergence, and the ultimate capacity of the United States to meet the challenges posed by microbial threats to human health. From the impact of war or technology on disease emergence to the development of enhanced disease surveillance and vaccine strategies, Microbial Threats to Health contains valuable information for researchers, students, health care providers, policymakers, public health officials. and the interested public.
| Author | : Committee on Emerging Microbial Threats to Health |
| Publisher | : National Academies |
| Total Pages | : 44 |
| Release | : 1992-01-01 |
| Genre | : Medical |
| ISBN | : |
The emergence of HIV disease and AIDS, the reemergence of tuberculosis, and the increased opportunity for disease spread through international travel demonstrate the critical importance of global vigilance for infectious diseases. This volume highlights risk factors for the emergence of microbial threats to health, warns against complacency in public health, and promotes early prevention as a cost-effective and crucial strategy for maintaining public health in the United States and worldwide. The volume identifies infectious disease threats posed by bacteria and viruses, as well as protozoans, helminths, and fungi. Rich in information, it includes a historical perspective on infectious disease, with focuses on Lyme disease, peptic ulcer, malaria, dengue, and recent increases in tuberculosis. The panel discusses how "new" diseases arise and how "old" ones resurge and considers the roles of human demographics and behavior, technology and industry, economic development and land use, international travel and commerce, microbial adaptation and change, and breakdown of public health measures in changing patterns of infectious disease. Also included are discussions and recommendations on disease surveillance; vaccine, drug, and pesticide development; vector control; public education and behavioral change; research and training; and strengthening of the U.S. public health system. This volume will be of immediate interest to scientists specializing in all areas of infectious dieseases and microbiology, healthy policy specialists, public health officials, physicians, and medical faculty and students, as well as anyone interested in how their health can be threatened by infectious diseases.
| Author | : Jun Lin |
| Publisher | : Frontiers Media SA |
| Total Pages | : 226 |
| Release | : 2015-06-01 |
| Genre | : Antibiotics |
| ISBN | : 2889195260 |
Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.
| Author | : Divya Arora |
| Publisher | : Springer |
| Total Pages | : 220 |
| Release | : 2019-01-09 |
| Genre | : Science |
| ISBN | : 3030018814 |
This book has been assembled with the hope of being an authoritative, comprehensive, conceptually sound and highly informative compilation of recent advances describing the concepts of bioengineering in the field of microbiology. It comprises of seven chapters written by eminent authors in their respective fields. Topics included deal with the significant advancement of microbial technology with emphasis on drug delivery strategies for healthcare products, vaccine delivery, biotransformation approaches to generate new molecules, upstream/downstream processing of biopharmaceuticals. It serves as excellent reference material for researchers, students and academicians in the fields of biotechnology, microbiology and pharmaceutical sciences.
| Author | : Enriqueta Garcia-Gutierrez |
| Publisher | : CRC Press |
| Total Pages | : 314 |
| Release | : 2024-02-06 |
| Genre | : Technology & Engineering |
| ISBN | : 1003854001 |
The aim of "Novel Approaches in Biopreservation for Food and Clinical Purposes" is to provide cutting-edge information on biopreservation methods for both food and medical applications. The book has one chapter dedicated to each major food category (milk and dairy, vegetables, meat, fish, bread, flours and beverages) and brief chapters covering preservation approaches for pharmaceuticals, embryos, gametes, cells and tissues. This book assumes a basic understanding of microbiology and food science, aiming to offer an overview of the most commonly and updated techniques currently used, including protective cultures and fermentation starters, bacterial metabolites, essential oils, bacteriophages or endolysins. By presenting this comprehensive overview, the book aims to advance knowledge in the field of biopreservation and foster its implementation in both food and clinical contexts.
| Author | : Tomás G. Villa |
| Publisher | : Springer |
| Total Pages | : 422 |
| Release | : 2019-08-13 |
| Genre | : Science |
| ISBN | : 3030218627 |
The book focuses on the evolutionary impact of horizontal gene transfer processes on pathogenicity, environmental adaptation and biological speciation. Newly acquired genetic material has been considered as a driving force in evolution for prokaryotic genomes for many years, with recent technical developments advancing this field further. However, the extent and implications of gene transfer between prokaryotes and eukaryotes still raise controversies. This multi-authored volume introduces various means by which DNA can be exchanged, covers gene transfer between prokaryotes and their viruses as well as between bacteria and eukaryotes, such as fungi, plants and animals, and addresses the role of horizontal gene transfer in human diseases. Aspects discussed also include the relevance for virulence and drug resistance development on one hand, and for the occurrence of naturally derived antibiotics and other secondary metabolites on the other hand. This book offers new insights to anyone interested in genome evolution and the exchange of DNA between the different domains of life, the genetic toolkit for adaptation and the emergence of multidrug resistant bacteria.
| Author | : Vijai G. Gupta |
| Publisher | : Elsevier |
| Total Pages | : 380 |
| Release | : 2019-06-14 |
| Genre | : Medical |
| ISBN | : 0444635114 |
New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Secondary Metabolites Biochemistry and Applications examines the areas of biotechnology and chemical engineering, covering aspects of plants, bacteria and machines, and using microbes as factories. The book is aimed at undergraduates, post-graduates and researchers studying microbial secondary metabolites, and is an invaluable reference source for biochemical engineers working in biotechnology, manipulating microbes, and developing new uses for bacteria and fungi. The applications of secondary metabolites in biotechnology, pharmaceuticals, diagnostics and medical device development are also extensively covered. The book integrates the aforementioned frontline branches into an interdisciplinary research work to satisfy those working in biotechnology, chemical engineering, alternative fuel development, diagnostics and pharmaceuticals. Chapters related to important research work on applications of microbial secondary metabolites are written by specialists in the various disciplines from the international community. - Compiles the latest developments in the area of microbial secondary metabolites - Authored by the top international researchers in this area - Includes information related to nearly all areas of a microbial secondary metabolites system
| Author | : |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2002 |
| Genre | : Cells |
| ISBN | : 9780815332183 |
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 164 |
| Release | : 2004-03-02 |
| Genre | : Technology & Engineering |
| ISBN | : 0309089778 |
In recent years much has happened to justify an examination of biological research in light of national security concerns. The destructive application of biotechnology research includes activities such as spreading common pathogens or transforming them into even more lethal forms. Policymakers and the scientific community at large must put forth a vigorous and immediate response to this challenge. This new book by the National Research Council recommends that the government expand existing regulations and rely on self-governance by scientists rather than adopt intrusive new policies. One key recommendation of the report is that the government should not attempt to regulate scientific publishing but should trust scientists and journals to screen their papers for security risks, a task some journals have already taken up. With biological information and tools widely distributed, regulating only U.S. researchers would have little effect. A new International Forum on Biosecurity should encourage the adoption of similar measures around the world. Seven types of risky studies would require approval by the Institutional Biosafety Committees that already oversee recombinant DNA research at some 400 U.S. institutions. These "experiments of concern" include making an infectious agent more lethal and rendering vaccines powerless.
