Key Heterocycle Cores for Designing Multitargeting Molecules

Key Heterocycle Cores for Designing Multitargeting Molecules
Author: Om Silakari
Publisher: Elsevier
Total Pages: 438
Release: 2018-06-11
Genre: Science
ISBN: 0081021054

Key Heterocycle Cores for Designing Multitargeting Molecules provides a helpful overview of current developments in the field. Following a detailed introduction to the manipulation of heterocycle cores for the development of dual or multitargeting molecules, the book goes on to describe specific examples of such developments, focusing on compounds such as Benzimidazole, Acridine, Flavones, Thiazolidinedione and Oxazoline. Drawing on the latest developments in the field, this volume provides a valuable guide to current approaches in the design and development of molecules capable of acting on multiple targets. Adapting the heterocyclic core of a single-target molecule can facilitate its development into an agent capable of acting on multiple targets. Such multi-targeting drugs have the potential to become essential components in the design of novel, holistic treatment plans for complex diseases, making the design of such active agents an increasingly important area of research. - Emphasizes the chemical development of heterocyclic nuclei, from single to multitargeting molecules - Provides chapter-by-chapter coverage of the key heterocyclic compounds used in synthesizing multitargeting agents - Outlines current trends and future developments in multitarget molecule design for the treatment of various diseases

Heterocyclic N-Oxides

Heterocyclic N-Oxides
Author: Oleg V. Larionov
Publisher: Springer
Total Pages: 163
Release: 2017-07-12
Genre: Science
ISBN: 3319606875

The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal.

Synthesis and Modification of Heterocycles by Metal-Catalyzed Cross-coupling Reactions

Synthesis and Modification of Heterocycles by Metal-Catalyzed Cross-coupling Reactions
Author: Tamás Patonay
Publisher: Springer
Total Pages: 371
Release: 2016-06-15
Genre: Science
ISBN: 3319326104

The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field.

Bioactive Heterocycles

Bioactive Heterocycles
Author: K. L. Ameta
Publisher: Nova Science Publishers
Total Pages: 0
Release: 2013
Genre: Bioactive compounds
ISBN: 9781622576364

This book is a critical and lucid account of various synthetic methodologies and biological activities of different sized bioactive heterocyclic compounds. In effect, this book imparts a great deal of comprehensive reviews about the chemistry and biology of selected groups of heterocycles and natural products including important pharmaceuticals as well as agrochemical pesticides in one handy project. Besides, this compendious effort encompasses different methods of synthesis and biological evaluation of heterocyclic compounds. The main purpose of this book is to share the recent advances and scope of Bioactive Heterocycles for the future avenues in the field. It has specifically been designed by keeping in mind the wide interests of individuals engaged in the design and synthesis of biologically active heterocyclic compounds as well as research scientists in academia and industry. The authors expect this book to be a standard reference in Universities and industrial libraries.

Structure, Bonding and Reactivity of Heterocyclic Compounds

Structure, Bonding and Reactivity of Heterocyclic Compounds
Author: Frank De Proft
Publisher: Springer
Total Pages: 199
Release: 2014-11-03
Genre: Science
ISBN: 3642451497

The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field.

Heterocycles as Chiral Auxiliaries in Asymmetric Synthesis

Heterocycles as Chiral Auxiliaries in Asymmetric Synthesis
Author: Manfred Braun
Publisher: Springer Nature
Total Pages: 326
Release: 2020-12-08
Genre: Science
ISBN: 3030453049

The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal.

Synthesis of Heterocycles in Contemporary Medicinal Chemistry

Synthesis of Heterocycles in Contemporary Medicinal Chemistry
Author: Zdenko Časar
Publisher: Springer
Total Pages: 281
Release: 2016-07-01
Genre: Science
ISBN: 3319399179

The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal.