New Treatment Perspectives In Autism Spectrum Disorders
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Author | : Roberto Canitano |
Publisher | : Frontiers Media SA |
Total Pages | : 162 |
Release | : 2015-04-17 |
Genre | : Autism |
ISBN | : 2889195309 |
Developing novel and more effective treatments that improve quality of life for individuals with autism spectrum disorders is urgently needed. To date a wide range of behavioral interventions have been shown to be safe and effective for improving language and cognition and adaptive behavior in children and adolescents with ASD. However many people with ASD can receive additional benefit from targeted pharmacological interventions. One of the major drawback in setting up therapeutics intervention is the remarkable individual differences found across individuals with ASD. As a matter of fact the medications that are currently available address only symptoms associated with ASD and not the core domains of social and communication dysfunction. The pathogenesis paradigm shift of ASD towards synaptic abnormalities moved the research to pathway to disease that involve multiple systems and that are becoming the forefront of ASD treatment and are pointing toward the development of new targeted treatments. Some new therapeutics have been tested and others are being studied. In this context single gene disorders frequently associated with ASD such as Rett Syndrome, Fragile X and Tuberous Sclerosis have been of significant aid as neurobiology of these disorders is more clear and has a potential to shed light on the altered signaling in ASD. However much research is needed to further understand the basic mechanisms of disease and the relationship to idiopathic ASD. Clinical trials in children are underway with agents directed to core symptoms and to the associated disorders in the search of new therapeutics and progress are expected with possible new option for therapeutics in ASD in the upcoming future. Children and Adolescents with ASD and their families can provide important information about their experience with new treatments and this should be a priority for future research. In addition, research performed on genetic mouse models of ASD will keep on providing useful information on the molecular pathways dysrupted in the disease, thus contributing to identify novel drug targets.
Author | : Susan P. Sherkow |
Publisher | : Rowman & Littlefield |
Total Pages | : 233 |
Release | : 2013-11-14 |
Genre | : Psychology |
ISBN | : 0765708639 |
Autism Spectrum Disorder: Perspectives from Psychoanalysis and Neuroscience, offers a guide to understanding and treating the ASD toddler from the dual perspectives of psychoanalysis and neurofunction through describing in great detail intensive treatments of four children who began therapy as toddlers. The authors hypothesize that dyadic therapy and Reflective Network Therapy can impact a child by modifying the biochemistry of the brain, resulting in alteration of emotion and cognition. Their chapter on neurobiological mechanisms of change describes these hypotheses in depth.
Author | : Andreas M. Grabrucker |
Publisher | : |
Total Pages | : 117 |
Release | : 2021 |
Genre | : |
ISBN | : |
Autism spectrum disorders are developmental disorders. Individuals with autism spectrum disorders develop differently. These differences are usually present in social interaction, communication, and sensory processing, and become visible through a wide variety of behavioral responses that differ from individuals without autism spectrum disorders. Despite significant research efforts, the exact causes of autism spectrum disorders remain poorly understood; however, researchers have gained extensive insights into possible pathomechanisms, even at the molecular level of cells. Many diagnostic criteria have been developed, adapted, and improved. The eight chapters in this book highlight the current state-of-the-art in many areas of autism spectrum disorders. Chapter 1 provides an overview of the epidemiology of autism spectrum disorders and the current knowledge of the underlying pathogenic mechanisms. Chapter 2 summarizes the diagnostic criteria and procedures and highlights present and upcoming therapeutic strategies. Chapter 3 reviews the adverse events and trauma in people with autism spectrum disorders. Chapters 4 and 5 focus on atypical sensory processing, and Chapter 6 discusses the genetic overlap of autism spectrum disorders with other neuropsychiatric disorders such as attention deficit hyperactivity disorder (ADHD), depression, and schizophrenia. Chapter 7 focuses on the contribution of abnormalities in mitochondria, and chapter 8 discusses gut-brain interactions and a potential role for microbiota in autism spectrum disorders. This book is aimed primarily at clinicians and scientists, but many areas will also be of interest to the layperson.
Author | : Amy M. Wetherby |
Publisher | : Brookes Publishing Company |
Total Pages | : 456 |
Release | : 2000 |
Genre | : Education |
ISBN | : |
A reference guide to autism spectrum disorders that provides an in-depth overview of the communication, language, social, and behavioral issues of autism spectrum disorders.
Author | : Joseph D. Buxbaum |
Publisher | : Academic Press |
Total Pages | : 494 |
Release | : 2012-10-25 |
Genre | : Medical |
ISBN | : 012391924X |
Autism is no longer considered a rare disease, and the Center for Disease Control now estimates that upwards of 730,000 children in the US struggle with this isolating brain disorder. New research is leading to greater understanding of and ability to treat the disorder at an earlier age. It is hoped that further genetic and imaging studies will lead to biologically based diagnostic techniques that could help speed detection and allow early, more effective intervention. Edited by two leaders in the field, this volume offers a current survey and synthesis of the most important findings of the neuroscience behind autism of the past 20 years. With chapters authored by experts in each topic, the volume explores etiology, neuropathology, imaging, and pathways/models. Offering a broad background of ASDs with a unique focus on neurobiology, the volume offers more than the others on the market with a strictly clinical focus or a single authored perspective that fails to offer expert, comprehensive coverage. Researchers and graduate students alike with an interest in developmental disorders and autism will benefit, as will autism specialists across psychology and medicine looking to expand their expertise. Uniquely explores ASDs from a neurobiological angle, looking to uncover the molecular/cellular basis rather than to merely catalog the commonly used behavioral interventions Comprehensive coverage synthesizes widely dispersed research, serving as one-stop shopping for neurodevelopmental disorder researchers and autism specialists Edited work with chapters authored by leaders in the field around the globe - the broadest, most expert coverage available
Author | : Neal Halfon |
Publisher | : Springer |
Total Pages | : 667 |
Release | : 2017-11-20 |
Genre | : Medical |
ISBN | : 3319471430 |
This book is open access under a CC BY 4.0 license. This handbook synthesizes and analyzes the growing knowledge base on life course health development (LCHD) from the prenatal period through emerging adulthood, with implications for clinical practice and public health. It presents LCHD as an innovative field with a sound theoretical framework for understanding wellness and disease from a lifespan perspective, replacing previous medical, biopsychosocial, and early genomic models of health. Interdisciplinary chapters discuss major health concerns (diabetes, obesity), important less-studied conditions (hearing, kidney health), and large-scale issues (nutrition, adversity) from a lifespan viewpoint. In addition, chapters address methodological approaches and challenges by analyzing existing measures, studies, and surveys. The book concludes with the editors’ research agenda that proposes priorities for future LCHD research and its application to health care practice and health policy. Topics featured in the Handbook include: The prenatal period and its effect on child obesity and metabolic outcomes. Pregnancy complications and their effect on women’s cardiovascular health. A multi-level approach for obesity prevention in children. Application of the LCHD framework to autism spectrum disorder. Socioeconomic disadvantage and its influence on health development across the lifespan. The importance of nutrition to optimal health development across the lifespan. The Handbook of Life Course Health Development is a must-have resource for researchers, clinicians/professionals, and graduate students in developmental psychology/science; maternal and child health; social work; health economics; educational policy and politics; and medical law as well as many interrelated subdisciplines in psychology, medicine, public health, mental health, education, social welfare, economics, sociology, and law.
Author | : Brian Reichow |
Publisher | : Springer Science & Business Media |
Total Pages | : 415 |
Release | : 2010-11-25 |
Genre | : Psychology |
ISBN | : 1441969756 |
Autism spectrum disorders (ASDs) have been increasingly diagnosed in recent years and carries with it far reaching social and financial implications. With this in mind, educators, physicians, and parents are searching for the best practices and most effective treatments. But because the symptoms of ASDs span multiple domains (e.g., communication and language, social, behavioral), successfully meeting the needs of a child with autism can be quite challenging. Evidence-Based Practices and Treatments for Children with Autism offers an insightful and balanced perspective on topics ranging from the historical underpinnings of autism treatment to the use of psychopharmacology and the implementation of evidence-based practices (EBPs). An evaluation methodology is also offered to reduce the risks and inconsistencies associated with the varying definitions of key autism terminology. This commitment to clearly addressing the complex issues associated with ASDs continues throughout the volume and provides opportunities for further research. Additional issues addressed include: Behavioral excesses and deficits treatment Communication treatment Social awareness and social skills treatment Dietary, complementary, and alternative treatments Implementation of EBPs in school settings Interventions for sensory dysfunction With its holistic and accessible approach, Evidence-Based Practices and Treatments for Children with Autism is a vital resource for school psychologists and special education professionals as well as allied mental health professionals, including clinical child and developmental psychologists, psychiatrist, pediatricians, primary care and community providers.
Author | : Dianne Zager |
Publisher | : Routledge |
Total Pages | : 595 |
Release | : 2004-09-22 |
Genre | : Education |
ISBN | : 1135623856 |
The field of autism has been growing at an unprecedented rate in recent years. In addition to an actual rise in the number of classic DSM-IV cases, broadened diagnostic criteria have uncovered a wider range of autistic behaviors and ability levels. The third edition of this well-known text continues the mission of its predecessors--to present a comprehensive, readable, up-to-date overview of the field of autism, one that links research, theory, and practice in ways that are accessible to both practitioners and parents. Key features include: *Expanded Coverage--To accommodate the recent explosion of research, the book has been expanded from 11 to 14 chapters that examine the impact of autism on the individual and the family from infancy through adulthood. *Expertise--Internationally recognized experts offer cutting-edge treatment and educational information on topics such as early diagnosis, medical treatment, assessment, educational methods, language development, behavior regulation, and family support. *Neurobiological Research--Comprehensive medical research and treatment chapters provide an understandable overview of neurobiological research and current treatments including when and how medication can be employed as part of a treatment plan. *Focus on Early Years--Old sections I and III have been combined and a new 3-chapter section on early identification and intervention added. *Focus on Parents and Families--In addition to a chapter on the evolving role of families, a new chapter addresses family needs during the preschool years. *Integration of Assessment and Intervention--The chapters on assessment and intervention have been reorganized and more closely integrated in keeping with current thinking about their inter-relatedness. *Future Directions--Two chapters discuss emerging directions in this exploding field and how to make informed decisions among a variety of approaches. This book is appropriate for anyone--students, practitioners, or parents--who must provide care for an autistic child.
Author | : Deborah Fein |
Publisher | : Oxford University Press |
Total Pages | : 559 |
Release | : 2011-06-09 |
Genre | : Psychology |
ISBN | : 0195378318 |
The Neuropsychology of Autism provides an up-to-date summary on the neuropsychology of autism spectrum disorders (ASD), written by leaders in the field. It summarizes current knowledge about neurochemistry, neuroanatomy, genetics, and clinical presentations and provides helpful discussions on key functions such as language, memory, attention, executive functions, social cognition, motor and sensory functioning.
Author | : Johnny L. Matson |
Publisher | : Elsevier |
Total Pages | : 447 |
Release | : 2011-09-02 |
Genre | : Psychology |
ISBN | : 0080559808 |
Autism spectrum disorder has received increasing research in recent years, with more information on assessment and treatment than can be readily assimilated from primary literature by clinicians. Clinical Assessment and Intervention for Autism Spectrum Disorders summarizes evidence-based assessments and intervention for Autism across the life-span, providing clinicians with a practical overview of how best to assess and treat this disorder. The book begins with a discussion of what warrants a determination of being "evidence based" and a description of the disorder from a life span perspective. The book also provides a chapter on differential diagnosis of autism relative to other disorders. What follows are separate sections on assessment and intervention. These chapters discuss first how to assess and then separately how to treat behavioral problems, communication and social skills issues, academic and vocational skills, and the use of pharmacology and an assessment of possible pharmacological effects. Intended for practitioners assessing and treating children with developmental delays, the book provides clinicians with best practices for assessing and treating delays associated with autism. - Covers the full range of Autism Spectrum Disorders - Covers the lifespan - Focuses on evidence-based assessment and treatment