Coxiella burnetii: Recent Advances and New Perspectives in Research of the Q Fever Bacterium

Coxiella burnetii: Recent Advances and New Perspectives in Research of the Q Fever Bacterium
Author: Rudolf Toman
Publisher: Springer Science & Business Media
Total Pages: 413
Release: 2012-06-19
Genre: Medical
ISBN: 9400743157

Coxiella burnetii is the etiological agent of Q fever, a zoonotic disease found worldwide. The bacterium is a fascinating example of intracellular parasitism that has uniquely evolved to thrive in the most inhospitable of cellular compartments-the phagolysosome. Understanding how C. burnetii resists the degradative functions of this vacuole, and the host cell functions coopted for successful parasitism, are central to understanding Q fever pathogenesis. Recent achievements in glycomics and proteomics are guiding development of enhanced detection schemes for the bacterium in addition to shedding light on the host immune response to the pathogen. Several chapters survey immune functions that control or potentially exacerbate Coxiella infection and delve into correlates of protective immunity elicited by vaccination. Comparative genomics is also the foundation of chapters discussing diagnostic antigen discovery and molecular typing of the bacterium, with significance for development of new clinical, epidemiologic, and forensic tools.

New Perspectives on Firm Growth

New Perspectives on Firm Growth
Author: Per Davidsson
Publisher: Edward Elgar Publishing
Total Pages: 353
Release: 2013-01-01
Genre: Business & Economics
ISBN: 0857933612

ÔThis collection of articles by an internationally recognized team of authors is a welcome addition to the literature on firm growth. The authors, singly and together, have previously made important contributions with regard to frameworks for understanding growth, as well as cutting-edge empirical research on the actual growth process. In this volume, the authors bring previous research up-to-date, providing a critical look at what has been published in the last decade and offering new theoretically informed insights in how and why firms grow.Õ Ð Howard Aldrich, University of North Carolina, US This insightful volume presents a collection of cutting-edge works by two of the leading researchers of firm growth. The studies extend previous research by providing stronger theoretical underpinnings and using longitudinal databases that can separate in time the firmsÕ growth from its presumed causes. They also break new ground by examining different modes of growth, such as sales growth vs. employment growth, and organic growth vs. acquisition-based expansion. Further, the studies investigate the drivers of firm growth and take a critical look at the effects, such as under what circumstances high growth is associated with high profitability. The issue of how firm growth is achieved and managed, and what consequences it has for different stakeholders is both theoretically interesting and practically important. The book will strongly appeal to academics of entrepreneurship, small business management and strategy.

New Perspectives on Industrial Organization

New Perspectives on Industrial Organization
Author: Victor J. Tremblay
Publisher: Springer Science & Business Media
Total Pages: 820
Release: 2012-07-20
Genre: Business & Economics
ISBN: 1461432413

This book covers the main topics that students need to learn in a course on Industrial Organization. It reviews the classic models and important empirical evidence related to the field. However, it will differ from prior textbooks in two ways. First, this book incorporates contributions from behavioral economics and neuroeconomics, providing the reader with a richer understanding of consumer preferences and the motivation for many of the business practices we see today. The book discusses how firms exploit consumers who are prone to making mistakes and who suffer from cognitive dissonance, attention lapses, and bounded rationality, for example and will help explain why firms invest in persuasive advertising, offer 30-day free trials, offer money-back guarantees, and engage in other observed phenomena that cannot be explained by the traditional approaches to industrial organization. A second difference is that this book achieves a balance between textbooks that emphasize formal modeling and those that emphasize the history of the field, empirical evidence, case studies, and policy analysis. This text puts more emphasis on the micro-foundations (i.e., consumer and producer theory), classic game theoretic models, and recent contributions from behavioral economics that are pertinent to industrial organization. Each topic will begin with a discussion of relevant theory and models and will also include a discussion of concrete examples, empirical evidence, and evidence from case studies. This will provide students with a deeper understanding of firm and consumer behavior, of the factors that influence market structure and economic performance, and of policy issues involving imperfectly competitive markets. The book is intended to be a textbook for graduate students, MBAs and upper-level undergraduates and will use examples, graphical analysis, algebra, and simple calculus to explain important ideas and theories in industrial organization.

New Perspectives in Marketing by Word-of-Mouth

New Perspectives in Marketing by Word-of-Mouth
Author: Emerald Group Publishing Limited
Publisher: Emerald Group Publishing
Total Pages: 201
Release: 2015-10-21
Genre: Business & Economics
ISBN: 1785608185

New Perspectives on Marketing by Word-of-Mouth offers insight to a world where consumers play an even bigger part in the building or breaking of a company's reputation. Some of the things the book will explain include:- How brand love is built in the fashion industry - How larger organisations effectively respond to negative social media.

New Perspectives on Yenching University, 1916-1952

New Perspectives on Yenching University, 1916-1952
Author: Arthur Lewis Rosenbaum
Publisher: BRILL
Total Pages: 448
Release: 2015-01-08
Genre: History
ISBN: 9004285245

Essays in New Perspectives on Yenching University, 1916·1952 reevaluate the experience of China's preeminent Christian university in an era of nationalism and revolution. Although the university was denounced by the Chinese Communists and critics as an elitist and imperialist enterprise irrelevant to China's real needs, the essays demonstrate that Yenching's emphasis on biculturalism, cultural exchange, and a broad liberal education combined with professional expertise ultimately are compatible with nation-building and a modern Chinese identity. They show that the university fostered transnational exchanges of knowledge, changed the lives of students and faculty, and responded to the pressures of nationalism, war, and revolution. Topics include efforts to make Christianity relevant to China's needs; promotion of professional expertise, gender relationships and coeducation; the liberal arts; Sino-American cultural interactions; and Yenching's ambiguous response to Chinese nationalism, Japanese invasion, and revolution.

Functional Inequalities: New Perspectives and New Applications

Functional Inequalities: New Perspectives and New Applications
Author: Nassif Ghoussoub
Publisher: American Mathematical Soc.
Total Pages: 331
Release: 2013-04-09
Genre: Mathematics
ISBN: 0821891529

"The book describes how functional inequalities are often manifestations of natural mathematical structures and physical phenomena, and how a few general principles validate large classes of analytic/geometric inequalities, old and new. This point of view leads to "systematic" approaches for proving the most basic inequalities, but also for improving them, and for devising new ones--sometimes at will and often on demand. These general principles also offer novel ways for estimating best constants and for deciding whether these are attained in appropriate function spaces. As such, improvements of Hardy and Hardy-Rellich type inequalities involving radially symmetric weights are variational manifestations of Sturm's theory on the oscillatory behavior of certain ordinary differential equations. On the other hand, most geometric inequalities, including those of Sobolev and Log-Sobolev type, are simply expressions of the convexity of certain free energy functionals along the geodesics on the Wasserstein manifold of probability measures equipped with the optimal mass transport metric. Caffarelli-Kohn-Nirenberg and Hardy-Rellich-Sobolev type inequalities are then obtained by interpolating the above two classes of inequalities via the classical ones of Hölder. The subtle Moser-Onofri-Aubin inequalities on the two-dimensional sphere are connected to Liouville type theorems for planar mean field equations."--Publisher's website.

Carcinomas: New Insights for the Healthcare Professional: 2013 Edition

Carcinomas: New Insights for the Healthcare Professional: 2013 Edition
Author:
Publisher: ScholarlyEditions
Total Pages: 1675
Release: 2013-07-22
Genre: Medical
ISBN: 1481663720

Carcinomas: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Carcinomas: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Carcinomas: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Simulation Modeling - Recent Advances, New Perspectives, and Applications

Simulation Modeling - Recent Advances, New Perspectives, and Applications
Author: Abdo Abou Jaoudé
Publisher: BoD – Books on Demand
Total Pages: 290
Release: 2024-09-11
Genre: Computers
ISBN: 183769706X

A simulation is the imitation of the operation of a real-world process or system over time. Simulations require the use of models in which a model represents the key characteristics or behaviors of the selected system or process and the simulation represents the evolution of the model over time. Computers are often used to execute simulations. This book provides a comprehensive overview of simulation modeling and explores its use to solve a large set of problems. It is a useful resource for scholars, researchers, and undergraduate and graduate students in pure and applied mathematics, physical sciences, engineering and technology, computer science, numerical analysis, scientific computing, and science in general.

New Perspectives on Pottery Mound Pueblo

New Perspectives on Pottery Mound Pueblo
Author: Polly Schaafsma
Publisher: UNM Press
Total Pages: 332
Release: 2007
Genre: Social Science
ISBN: 9780826339065

Noted archaeologist Polly Schaafsma presents new research by current scholars on this largely neglected ancestral Puebloan site.