New Oxidoreductases For The Synthesis Of Chiral Building Blocks
Download New Oxidoreductases For The Synthesis Of Chiral Building Blocks full books in PDF, epub, and Kindle. Read online free New Oxidoreductases For The Synthesis Of Chiral Building Blocks ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
The Synthesis of Chiral Building Blocks Using Beta-hydroxy Sulfoxide Dianions
Author | : Carla M. Edwards |
Publisher | : |
Total Pages | : 476 |
Release | : 1992 |
Genre | : Organic compounds |
ISBN | : |
Biocatalysis for Practitioners
Author | : Gonzalo de Gonzalo |
Publisher | : John Wiley & Sons |
Total Pages | : 54 |
Release | : 2021-07-19 |
Genre | : Science |
ISBN | : 352734683X |
This reference book originates from the interdisciplinary research cooperation between academia and industry. In three distinct parts, latest results from basic research on stable enzymes are explained and brought into context with possible industrial applications. Downstream processing technology as well as biocatalytic and biotechnological production processes from global players display the enormous potential of biocatalysts. Application of "extreme" reaction conditions (i.e. unconventional, such as high temperature, pressure, and pH value) - biocatalysts are normally used within a well defined process window - leads to novel synthetic effects. Both novel enzyme systems and the synthetic routes in which they can be applied are made accessible to the reader. In addition, the complementary innovative process technology under unconventional conditions is highlighted by latest examples from biotech industry.
Application of Saccharomyces Carlsbergensis Old Yellow Enzyme in Synthesis of Chiral Ketones and Building Blocks for [beta]-amino Acids
Author | : Magdalena Alicja Swiderska |
Publisher | : |
Total Pages | : |
Release | : 2007 |
Genre | : |
ISBN | : |
ABSTRACT: This dissertation describes the application of S. carlsbergensis Old Yellow Enzyme (an NADPH dependent yeast oxidoreductase) in the biotransformation of different types of activated alkenes. Two classes of compounds, substituted cyclohexenones and [beta]-nitroacrylates, were synthesized and tested as potential substrates for OYE.
Chirality in Drug Design and Synthesis
Author | : C. Brown |
Publisher | : Academic Press |
Total Pages | : 264 |
Release | : 2013-10-22 |
Genre | : Social Science |
ISBN | : 1483288242 |
Chirality in Drug Design and Synthesis is a collection of papers that discusses the property of asymmetry in the structural and synthetic chemistry of natural products, including the significance of chirality in medicinal chemistry. These papers examine the need for the preparation and study of pure enantiomers of chiral drug substances and their mechanism of interaction with enzymes and receptors. These papers also investigate the techniques in studying these interactions, as well as analyze the methods for their synthesis in enantiomerically pure form. One paper discusses the pharmacological and pharmacokinetic analyses made that point to the differences in the activity and disposition of enantiometric pairs. Another paper reviews the implications of the neglect of stereoselectivity at the different levels during the examination process of racemic drugs. Since no general guidelines exists for the development of drugs with chiral centers, one paper suggests a case-by-case approach in evaluating the safety and efficacy of drugs, particularly as regards how isomers differ in their effects. This collection is suitable for the pharmacologist, medicinal chemists, toxicologists, mechanistic chemists and synthetic organic chemists.
Modern Biocatalysis
Author | : Gavin Williams |
Publisher | : Royal Society of Chemistry |
Total Pages | : 594 |
Release | : 2018-05-31 |
Genre | : Science |
ISBN | : 1788014537 |
The synergy between synthetic biology and biocatalysis is emerging as an important trend for future sustainable processes. This book reviews all modern and novel techniques successfully implemented in biocatalysis, in an effort to provide better performing enzymatic systems and novel biosynthetic routes to (non-)natural products. This includes the use of molecular techniques in protein design and engineering, construction of artificial metabolic pathways, and application of computational methods for enzyme discovery and design. Stress is placed on current ‘hot’ topics in biocatalysis, where recent advances in research are defining new grounds in enzyme-catalyzed processes. With contributions from leading academics around the world, this book makes a ground-breaking contribution to this progressive field and is essential reading for graduates and researchers investigating (bio)catalysis, enzyme engineering, chemical biology, and synthetic biology.
Asymmetric Synthesis with Chemical and Biological Methods
Author | : Dieter Enders |
Publisher | : John Wiley & Sons |
Total Pages | : 472 |
Release | : 2007-04-09 |
Genre | : Science |
ISBN | : 3527314733 |
Edited by two of the leading researchers in the field, this book provides a deep, interdisciplinary insight into stoichiometric and catalytic reactions in this continuously expanding area. A plethora of top German scientists with an international reputation covers various aspects, from classical organic chemistry to process development, and from the theoretical background to biological methods using enzymes. Throughout the focus is on the development of new synthetic methods in asymmetric synthesis, the synthesis of natural and bioactive compounds and the latest developments in both chemical and biological methods of catalysis, as well as the investigation of special technical and biotechnical aspects.