Neurotoxicity Of Metals
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| Author | : |
| Publisher | : Elsevier |
| Total Pages | : 546 |
| Release | : 2015-11-09 |
| Genre | : Medical |
| ISBN | : 044462628X |
Occupational Neurology a volume in the Handbook of Clinical Neurology Series, provides a comprehensive overview of the science, clinical diagnosis, and treatment for neurotoxin related neurological and psychiatric disorders. This timely collection provides not only a complete scientific reference on the chemical origin of this class of neurological and psychiatric disorders, but also a practical guide to diagnosis and treatment challenges and best practices. Handbook of Clinical Neurology Series The first volume of the Handbook of Clinical Neurology under the editorship of George Bruyn and Pierre Vinken was published in 1968. In 1982, the series was brought to an interim conclusion with the publication of the cumulative index volume (Volume 44). By that stage, the Handbook had come to represent one of the largest scientific works ever published. It enjoys a high reputation in specialist media circles throughout the world. After the series was concluded in 1982, it was realized that an update of the material was imperative. Accordingly, a revised series was planned and published over the following years, concluding with the publication of another cumulative index to both series (Volume 76-78) in 2002. Since then, George Bruyn has passed away and Pierre Vinken has retired, but the need for a further new series, incorporating advances in the field, again become necessary. Professors Michael J. Aminoff, François Boller and Dick F. Swaab have with enthusiasm taken on the responsibility of supervising the preparation of a third series, the first volumes of which were published in 2003. Now, more than 130 volumes after the first published, the Handbook of Clinical Neurology series continues to have an unparalleled reputation for providing the latest foundational research, diagnosis, and treatment protocols essential for both basic neuroscience research and clinical neurology. - Provides comprehensive coverage of neurotoxins, especially in the workplace - Details the latest science as the foundation for neurotoxicity diagnosis and treatment - Presents coverage of the diagnosis and treatment essential for clinical neurologists and occupational medicine specialists
| Author | : Kavindra Kumar Kesari |
| Publisher | : Springer |
| Total Pages | : 189 |
| Release | : 2019-05-25 |
| Genre | : Medical |
| ISBN | : 3319965115 |
This book covers the latest environmental issues based on current research objectives. All chapters are fundamentally interlinked and focus on deciphering the networking of mutagens in environmental toxicity and human health. Our changing environment, climate, and lifestyle factors are growing concerns in the 21st century. The existing mutagens, either physical or chemical, are responsible for environmental toxicity. These toxicants are carcinogenic and not limited to naturally occurring chemicals or biologicals, but can also be man-made, such as 'radiation'. The networking of mutagens can have a broad range of effects on both the environment and human health. Accordingly, the respective chapters explore the networking of mutagens in connection with environmental toxicity, and address: 1. Extant types of man-made radiation and their effects on the environment and biological systems2. Heavy metal contaminations: Effects on environmental health3. Networking of environmental pollutants in the air, dust, soil, water, and natural toxins in the environment: Exposure and health4. The molecular interaction of environmental carcinogens with DNA: An oncoinformatics approach5. Fundamentals of nonotoxicity, carcinogenicity, mutagenic and neurotoxicity in environmental health6. The role of antioxidants and medicinal plants in reducing the impacts of disease-causing pollutants A sequel to Perspectives in Environmental Toxicology, this book highlights the latest developments in the field of environmental toxicology. It offers a valuable resource for researchers, scholars and graduate students alike.
| Author | : Ozgur Karcioglu |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 130 |
| Release | : 2019-06-19 |
| Genre | : Medical |
| ISBN | : 1838807853 |
Over 400 years ago, Swiss alchemist and physician Paracelsus (1493-1541) cited: "All substances are poisons; there is none that is not a poison. The right dose differentiates a poison from a remedy." This is often condensed to: "The dose makes the poison." So, why are we overtly anxious about intoxications?In fact, poisons became a global problem with the industrial revolution. Pesticides, asbestos, occupational chemicals, air pollution, and heavy metal toxicity maintain high priority worldwide, especially in developing countries. Children between 0 and 5 years old are the most vulnerable to both acute and chronic poisonings, while older adults suffer from the chronic effects of chemicals. This book aims to raise awareness about the challenges of poisons, to help clinicians understand current issues in toxicology.
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 167 |
| Release | : 1992-02-01 |
| Genre | : Science |
| ISBN | : 0309045312 |
Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.
| Author | : Kedar N. Prasad |
| Publisher | : Chapman & Hall/CRC |
| Total Pages | : 208 |
| Release | : 1988 |
| Genre | : Medical |
| ISBN | : |
| Author | : Saravanan Rajendran |
| Publisher | : Springer Nature |
| Total Pages | : 360 |
| Release | : 2021-01-25 |
| Genre | : Science |
| ISBN | : 3030564134 |
This book presents recent advances in inorganic nanomaterials for healthcare, with focus on the synthesis, medical applications and toxicity of metals, metal oxides and metal sulfides. Major applications include diagnosis, bioimaging, biosensing, healing and therapy in cancer, diabetes, cardiovascular diseases, obesity, metabolic syndrome, dentistry and antimicrobials.
| Author | : Michael Aschner |
| Publisher | : Springer |
| Total Pages | : 383 |
| Release | : 2017-09-18 |
| Genre | : Medical |
| ISBN | : 9783319601885 |
Assembles international authorities to address contemporary research in metal neurotoxicity. Essential and non-essential metals play an important role in neurodevelopmental and neurodegenerative diseases. Recent developments in understanding the role of metals in the etiology of these disorders have led to rapid growth in clarifying the pathology of some of the most devastating diseases we face and in identifying potential new therapies. Few books or periodicals have been wholly dedicated to the topic of metals, and this collection is intended to serve as a resource for all researchers interested in metals and their role in health and disease.
| Author | : Robert R Crichton |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 336 |
| Release | : 2016-10-18 |
| Genre | : Science |
| ISBN | : 1782623892 |
Metal chelators are emerging as versatile tool with many medical applications. Their versatility allows them to be used in chelation therapy for treating diseases caused by toxic and heavy metal poisoning, chelating agents are capable of binding to toxic metal ions to form complex structures which are easily excreted from the body removing them from intracellular or extracellular spaces. In addition, metal chelators can also be applied as contrast agents in MRI scanning. Metal Chelation in Medicine provides a clear and timely perspective on the role of chelating agents in the management of metal intoxications and storage diseases. Written by leaders in the field of chelators, this publication is at the cutting-edge of the subject. It covers a broad range of topics such as the use of metal chelators in non-invasive assessment of brain iron overload, and the treatment of systemic iron overload and neurodegenerative diseases. As such it is particularly valuable to clinicians treating metal poisonings and metal storage diseases. However, it is also a useful text for researchers, industry professionals and university students with a specific interest in medicinal chemistry, chelation, metal ions, imaging and non-invasive techniques.
| Author | : Louis W. Chang |
| Publisher | : CRC Press |
| Total Pages | : 1232 |
| Release | : 1996-08-02 |
| Genre | : Science |
| ISBN | : 9780873718035 |
This volume offers the most comprehensive presentation available on metal toxicology. It discusses not only metals but also the toxic endpoints, such as neurotoxicity, renal toxicity, and cancer induction. Chapters are written by experts in their respective fields, focusing on carcinogenesis and human exposures and highlighting the major aspects and issues of toxicity in general.
| Author | : Qiao Niu |
| Publisher | : Springer |
| Total Pages | : 191 |
| Release | : 2018-10-12 |
| Genre | : Medical |
| ISBN | : 9811313709 |
This book reviews the scientific literature and the authors’ own research linking aluminum neurotoxicity with cognitive impairment and Alzheimer’s disease (AD). It focuses on aluminum levels in the brain, region-specific and subcellular distribution, and its relation to neurofibrillary tangles and amyloid beta. Further, the book stresses the importance of aluminum’s complex speciation chemistry in relation to biology, and details aluminum’s mechanism in oxidative stress and cell death, especially in connection with apoptosis and necroptosis. The electrophysiological variation and synaptic plasticity induced by aluminum are covered, while the metal’s debatable role in AD and the cross-talk between aluminum and genetic susceptibility are also discussed. In closing, the book reviews the neurotoxic effects of aluminum and its important role in the pathogenesis of AD. Given its depth of coverage, the book provides readers with a systematic summary of aluminum neurotoxicity.
