During the past decade, we have witnessed explosive growth in the neurosciences: structural and functional brain imaging, electrophysiology and electrodiagnosis, cell and molecular biology, genetics, and neuropsychopharmacology-to name just a few. First published 15 years ago as the only multiauthored, comprehensive textbook in the field, the fourth edition of this tremendously successful volume expands its focus on the neurosciences to encompass the great strides we've made. To convey this intensified focus, the editors have added " "and Clinical Neurosciences"" to the title, with new and expanded chapters that cover topics such as the epidemiology and genetics of neuropsychiatric disorders, the neuropsychiatric aspects of delirium, the growth in clinical knowledge and clinical relevance of drug-induced delirium and encephalopathies other than delirium, and educational and certification issues in neuropsychiatry (including the requisite knowledge base and educational experience defined by the American Neuropsychiatric Association). In compiling this informative and enjoyable compendium, the editors have crafted each chapter as a complete stand-alone entity, necessitating some intentional overlap among chapters within its six broad sections on basic principles, assessment, symptomatologies, disorders, treatments, and special topics. With a remarkable 85 contributors-all recognized experts-this comprehensive text is clinically relevant and eminently practical for medical students and residents, psychiatrists, neurologists, psychologists and neuropsychologists, and a broad range of professionals who work in many different clinical settings (e.g., the general hospital setting, physical medicine/rehabilitation hospitals, psychiatric institutes, community mental health centers, alcohol and chemical dependency programs, and outpatient services and doctors' offices).