Neuroprogression In Psychiatric Disorders
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| Author | : Flávio Kapczinski |
| Publisher | : Oxford University Press |
| Total Pages | : 248 |
| Release | : 2019-03-05 |
| Genre | : Medical |
| ISBN | : 0191090883 |
Recent studies regarding the neuropathology of specific neurological disorders suggest that both neurodevelopmental and neurodegenerative processes may play a role. However, in contrast to the neurodegeneration seen in neurological disorders such as Parkinson's and Alzheimer's disease, the term "neuroprogression" has been used to describe the neurodevelopmental aspect of pathological brain re-wiring that takes place in the context of severe psychiatric disorders, such as schizophrenia or bipolar disorder. Within psychiatry, patients with severe psychopathology, such as those depressed patients who eventually commit suicide, have been shown to present with increased inflammatory markers in the brain. A similar increase in inflammatory markers is also found in patients with bipolar disorders and schizophrenia. Thus, oxidative stress, inflammation, and changes in growth factors are thought to be the pathways of neuroprogression. Neuroprogression in Psychiatry provides a comprehensive summary of the current developments in the emerging field of neuroprogression. With contributions by leading researchers in the field, this book examines the role of neuroprogression across a wide range of specific psychiatric disorders, with chapters included on major depressive disorder, anxiety disorder, post-traumatic stress disorder, substance abuse, schizophrenia, and bipolar disorder.
| Author | : Jair Soares |
| Publisher | : Academic Press |
| Total Pages | : 0 |
| Release | : 2018-06-12 |
| Genre | : Medical |
| ISBN | : 9780128123478 |
Bipolar Disorder Vulnerability: Perspectives from Pediatric and High-Risk Populations synthesizes our current understanding of high-risk and pediatric populations to aid readers in identifying markers of vulnerability for the development of bipolar disorder, with an ultimate goal of the development of drug targets and other therapies for early diagnosis and treatment. The book provides readers with an understanding of biological and environmental factors influencing disease manifestation that will aid them in defining discrete clinical stages and, importantly, establish an empirical basis for the application of novel therapeutics in a phase of illness during which specific treatments could more effectively alter disease course. Whereas most of the literature available on the pathophysiological mechanisms of bipolar disorder focuses on chronically ill adult individuals, this represents the only book that specifically examines pediatric and high-risk populations. An estimated 30 to 60 percent of adult bipolar disorder patients have their disease onset during childhood, with early-onset cases representing a particularly severe and genetically loaded form of the illness.
| Author | : A. Halaris |
| Publisher | : Karger Medical and Scientific Publishers |
| Total Pages | : 192 |
| Release | : 2017-07-25 |
| Genre | : Psychology |
| ISBN | : 3318060518 |
In this volume, international experts critically review cutting-edge advances in neuroprogression research. The relevance of these findings to psychiatric and neurological disorders is clarified. Potential etiopathological mechanisms of neuroprogression are described in detail. Special emphasis is placed on the role of the immune system in stress and stress-related disorders and brain-immune interactions. The epigenetic consequences of adverse experiences in early childhood, which may prelude major psychiatric disorders, are also considered. Recent research has not only provided evidence of neuroprogression in psychiatric and neurological disorders, but has shown that pharmacologic interventions have the potential to arrest this process. Advances in testing and imaging will lead to timely diagnosis and earlier treatment. Identification of neurological mechanisms alongside (epi-)genetic vulnerability markers will create truly personalized treatment programs. This book is a valuable resource for everyone who wishes to gain insight into the essential features of the neuroprogressive course of major psychiatric and neurological disorders. In particular, psychiatrists, neuroscientists and neurologists ¬ as well as immunologists, pharmacologists and molecular biologists - will find very informative chapters of direct relevance to their field.
| Author | : Joao L. de Quevedo |
| Publisher | : Academic Press |
| Total Pages | : 472 |
| Release | : 2020-11-25 |
| Genre | : Medical |
| ISBN | : 012819183X |
The Neurobiology of Bipolar Disorder: Road to Novel Therapeutics combines the basic neurobiology of bipolar disorder with discussions of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of bipolar disorder, genetic approaches and the pharmacogenomics of bipolar disorder. The basic foundational understanding of the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research combine to aid advanced students and researchers in their understanding of bipolar disorder management using novel and fast-acting pharmaceutical and neuromodulatory approaches. - Aids readers in understanding bipolar disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations - Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments to novel therapeutics - Synthesizes a discussion of the cellular and molecular mechanisms underlying symptoms with clinical aspects of bipolar disorder
| Author | : Flávio Kapczinski |
| Publisher | : Oxford University Press (UK) |
| Total Pages | : 357 |
| Release | : 2015 |
| Genre | : Medical |
| ISBN | : 0198709994 |
Neuroprogression and Staging in Bipolar Disorder provides a comprehensive and scholarly overview of clinical staging systems in the management of bipolar disorder. The book covers the theoretical basis, the neurobiological underpinnings, the current evidence base, limitations, future directions and the clinical implications and recommendations.
| Author | : Johannes Hebebrand |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 197 |
| Release | : 2018-12-07 |
| Genre | : Medical |
| ISBN | : 0323548539 |
Get a quick, expert overview of best practices for diagnosis and treatment of eating disorders in children and adolescents. This concise resource by Drs. Johannes Hebebrand and Beate Herpertz-Dahlmann provides psychiatrists and pediatricians with current information in this increasingly important field, including practical sections on developmental aspects of eating disorders, symptomology, epidemiology, etiology and pathyphysiology, treatment and outcomes, and prevention. - Discusses general concepts for feeding, eating, and weight disorders; body weight and composition, appetite regulation, and the emergence of body perception and image. - Covers genetics of eating and weight disorders, influence of hormones, intergenerational effects, and food addiction. - Includes information on cognitive behavioral therapy, family-based therapies, early intervention, pharmacotherapy, bariatric surgery, and other treatments. - Consolidates today's available information on this timely topic into a single convenient resource.
| Author | : Bernhard Baune |
| Publisher | : Academic Press |
| Total Pages | : 638 |
| Release | : 2018-05-23 |
| Genre | : Medical |
| ISBN | : 0128110740 |
Inflammation and Immunity in Depression: Basic Science and Clinical Applications is the first book to move beyond the established theory of cytokine-induced depression and explore the broader role the immune system plays in this devastating mood disorder. The book fully explores the most recent lines of research into this rapidly advancing field, including alterations of T-cells, the neurobiological implications of neuroinflammation and immune alterations for brain development and function, and the genetic components of neuroinflammation in depression, including the relationships between stress and inflammation that are revealing gene-environment interactions in the disorder. Combining contributions from researchers worldwide, this book provides the most comprehensive discussion available today on the involvement of the innate immune and adaptive immune systems in depressive disorder. Chapters span neuroscience, psychology, clinical applications and future directions, making this book an invaluable resource for advanced students, researchers and practitioners who need to understand the complex and varied role of inflammation and immune responses in depression. - Synthesizes current knowledge of inflammation and immunity in depression, ranging from basic neuroscience research, to clinical applications in psychiatry - Expands on the long-established theory of cytokine-induced depression to discuss broader involvement of the immune system - Explores translational potential of targeting immune dysfunction for clinical interventions
| Author | : Ather Muneer |
| Publisher | : Routledge |
| Total Pages | : 347 |
| Release | : 2018-02-01 |
| Genre | : Medical |
| ISBN | : 1351370774 |
Mood Disorders: Practical Issues in Diagnosis and Management provides cutting edge knowledge about the diagnosis and treatment of principal mood disorders, namely major depressive disorder and bipolar disorder. Covering diagnosis, differentiating features, and illness course and trajectories of principal mood disorders, Dr. Ather Muneer provides essential information in a succinct and practical manner, while highlighting significant new findings in the area. This book will help a broad range of mental health professionals better treat the millions of people with mood disorders across the globe.
| Author | : Allan H. Young |
| Publisher | : Springer Nature |
| Total Pages | : 325 |
| Release | : 2021-03-29 |
| Genre | : Medical |
| ISBN | : 3030721434 |
Bipolar disorder is a common, complex and costly mental health disorder, which sits at the heart of the practice of clinical psychiatry. Effective treatments (pharmacological, psychological and brain stimulation based) have all been discovered serendipitously. With the huge advances in basic neuroscience the way is now clear for novel treatments to be developed based on brain science. This book reviews these possibilities.
| Author | : David Castle |
| Publisher | : Cambridge University Press |
| Total Pages | : 287 |
| Release | : 2021-03-11 |
| Genre | : Medical |
| ISBN | : 1108740421 |
A complete and accessible textbook covering current understandings about how mental health issues affect men, and the available treatments.
