Neuropeptides And Immunoregulation
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| Author | : Berta Scharrer |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 183 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 3642784801 |
This book provides an updated overview of a rapidly develo- ping and exciting area of investigation dealing with the ro- le of neuropeptides in immunoregulatory processes. Existing texts focus on the bidirectional exchange of signals among the nervous, endocrine and immune systems in mammals, car- ried out primarily by the enkephalin and proopiomelanocortin families of neuropeptides and lymphokines. This collection of material is the first one to include pertinent informa- tion obtained in invertebrates, which has considerably ad- vanced our knowledge of the role of opioid neuropeptides, especiallyin another activity of the immune system, that of autoregulation. The study and interpretation of the remark- able parallelisms between these phenomena observed in inver- tebrates and vertebrates bring new insight into the me- chanisms of neuroimmunobiological integration with both general biological and clinical implications.
| Author | : W. Savino |
| Publisher | : Karger Medical and Scientific Publishers |
| Total Pages | : 190 |
| Release | : 2017-02-28 |
| Genre | : Medical |
| ISBN | : 3318060143 |
In the last decades, several in vitro and in vivo studies have revealed the existence of a very complex network between the neuroendocrine and immune system. Important molecular mechanisms underlying these interactions, in both physiological and pathological conditions, have also been described. Indeed, hormones play a pivotal role in the development and functional regulation of the immune system – both innate and acquired responses. Immune system cells present specific hormone receptors and themselves produce some hormones, thus influencing hormone secretion. More recently, the modulation of hormone secretion has been attempted for treating associated autoimmune disorders, further supporting the strong interplay between the endocrine and immune system. Distinguished experts, who have published extensively in their fields, have contributed comprehensive chapters to this volume. The focus is on the various aspects of endocrine-neuro-immune connections, providing an updated panorama - from basics to clinical applications - of current knowledge and still debated issues.
| Author | : Federico Bermudez-Rattoni |
| Publisher | : CRC Press |
| Total Pages | : 368 |
| Release | : 2007-04-17 |
| Genre | : Psychology |
| ISBN | : 1420008412 |
A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq
| Author | : Mia Levite |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 374 |
| Release | : 2012-02-14 |
| Genre | : Medical |
| ISBN | : 3709108888 |
“Nerve-Driven Immunity: Neurotransmitters and Neuropeptides in the Immune System” summarizes, analyzes and sheds new light on an unrecognized, yet very important role of key neurotransmitters and neuropeptides in the immune system. Each chapter of the book deals with a different neurotransmitter/neuropeptide from the following list: Dopamine, Adrenaline, Noradrenaline, Acetylcholine, Glutamate, GABA, Somatostatin, Neuropeptide Y (NPY), Vasoactive intestinal polypeptide (VIP), Calcitonin gene related peptide (CGRP), Opioids and Cannabinoids. For each of these neurotransmitters/neuropeptides, the following four topics are discussed: The specific receptors for the neurotransmitter/neuropeptide expressed in various types of immune cells The direct effects induced by the neurotransmitter/neuropeptide in various types of immune cells (either resting or activated), and the specific immune functions and features it activates/elevates or rather inhibits in specific concentrations The production of the neurotransmitter/neuropeptide in, and its release by, various types of immune cells The involvement of the neurotransmitter/neuropeptide in various diseases of the immune system (among them autoimmune diseases, immunodeficiency diseases and hematological cancers) The book includes many original figures, overview tables, and proposed models of events which are instrumental, enriching and stimulating for the reader. In light of the above-mentioned aspects, “Nerve-Driven Immunity: Neurotransmitters and Neuropeptides in the Immune System” is ideally suited as a textbook for new courses in Immunology, Neurology, Neuro-immunology or Pharmacology. The book chapters were written by highly skilled authors from 10 countries: the USA, the United Kingdom, Italy, Israel, Sweden, France, Germany, Spain, Serbia and Romania. “Nerve-Driven Immunity” is a term first coined by Dr. Mia Levite (the editor of the book).
| Author | : Thue W. Schwartz |
| Publisher | : |
| Total Pages | : 458 |
| Release | : 1990 |
| Genre | : Neurochemistry |
| ISBN | : |
| Author | : Richard Coico |
| Publisher | : John Wiley & Sons |
| Total Pages | : 432 |
| Release | : 2015-01-28 |
| Genre | : Medical |
| ISBN | : 1118396898 |
Immunology: A Short Course, 7th Edition introduces all the critical topics of modern immunology in a clear and succinct yet comprehensive fashion. The authors offer uniquely-balanced coverage of classical and contemporary approaches and basic and clinical aspects. The strength of Immunology: A Short Course is in providing a complete review of modern immunology without the burden of excessive data or theoretical discussions. Each chapter is divided into short, self-contained units that address key topics, illustrated by uniformly drawn, full-color illustrations and photographs. This new edition of Immunology: A Short Course: • Has been fully revised and updated, with a brand new art program to help reinforce learning • Includes a new chapter on Innate Immunity to reflect the growth in knowledge in this area • Highlights important therapeutic successes resulting from targeted antibody therapies • Includes end of chapter summaries and review questions, a companion website at www.wileyimmunology.com/coico featuring interactive flashcards, USMLE-style interactive MCQs, figures as PowerPoint slides, and case-based material to help understand clinical applications
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 722 |
| Release | : 1999-05-13 |
| Genre | : Medical |
| ISBN | : 0309173183 |
Every aspect of immune function and host defense is dependent upon a proper supply and balance of nutrients. Severe malnutrition can cause significant alteration in immune response, but even subclinical deficits may be associated with an impaired immune response, and an increased risk of infection. Infectious diseases have accounted for more off-duty days during major wars than combat wounds or nonbattle injuries. Combined stressors may reduce the normal ability of soldiers to resist pathogens, increase their susceptibility to biological warfare agents, and reduce the effectiveness of vaccines intended to protect them. There is also a concern with the inappropriate use of dietary supplements. This book, one of a series, examines the impact of various types of stressors and the role of specific dietary nutrients in maintaining immune function of military personnel in the field. It reviews the impact of compromised nutrition status on immune function; the interaction of health, exercise, and stress (both physical and psychological) in immune function; and the role of nutritional supplements and newer biotechnology methods reported to enhance immune function. The first part of the book contains the committee's workshop summary and evaluation of ongoing research by Army scientists on immune status in special forces troops, responses to the Army's questions, conclusions, and recommendations. The rest of the book contains papers contributed by workshop speakers, grouped under such broad topics as an introduction to what is known about immune function, the assessment of immune function, the effect of nutrition, and the relation between the many and varied stresses encountered by military personnel and their effect on health.
| Author | : Alexander W. Kusnecov |
| Publisher | : John Wiley & Sons |
| Total Pages | : 552 |
| Release | : 2013-12-31 |
| Genre | : Psychology |
| ISBN | : 111997951X |
This comprehensive resource details the history, methodology and development of research into psychoneuroimmunology, balancing it with meticulous coverage of both the clinical aspects and practical applications of the subject. A much-needed reference including overviews of key advances in the field Discusses how psychoneuroimmunological research is conceived and executed Includes contributions from a wealth of experts in the field Forward by Robert Ader and Nicholas Cohen, founders of the discipline Authoritative and interdisciplinary in scope - integrating biological and behavioral science
| Author | : Zofia Zukowska |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 264 |
| Release | : 2006-01-17 |
| Genre | : Medical |
| ISBN | : 3764374276 |
Recent research indicates that the immune system and inflammatory reactions are governed and regulated by powerful neuronal mediators derived from the central and peripheral nervous system. The NPY family of peptides is a diverse group of neuropeptides that acts via multiple receptors, Y1-Y5, which are widespread not only in neurons but also in a variety of non-neural and immune cells. These peptides have been known as important regulators of many essential systems, such as blood pressure and cardiac function, food consumption and energy homeostasis. However, in recent years, they have also become recognized for their role as potent modulators of cell growth and immune functions with broad implications in chronic inflammatory diseases, cancer and angiogenesis. In this book, experts in the field analyze recent evidence supporting the role of NPY family of peptides in regulation of the immune/inflammatory system with special reference to its medical and therapeutic implications.
| Author | : Fleur L. Strand |
| Publisher | : MIT Press |
| Total Pages | : 678 |
| Release | : 1999 |
| Genre | : Medical |
| ISBN | : 9780262194075 |
This textbook is the first to bring together and synthesize the neuropeptide research of the past decade in such a comprehensive, scholarly manner. In recent years there has been increasing interest and, subsequently, active research in neuropeptides. These neuroactive molecules coordinate, integrate, and regulate physiological processes in all organisms, throughout all phases of development. Acting as neurohormones, neurotransmitters, and/or neuromodulators, they maintain physiological homeostasis and influence important behavioral patterns. This textbook is the first to bring together and synthesize the neuropeptide research of the past decade in such a comprehensive, scholarly manner. The book is divided into two parts. In Part I the author defines the basic principles of neuropeptide action, including their biosynthesis, processing, transport, distribution, and interactions with receptors and second messenger systems. Strand also discusses the intimate interaction between the neuropeptides, stress, and the immune system. In Part II she discusses the regulatory functions of the families of neuropeptide in sufficient detail to provide both the advanced student and senior investigator with a thorough understanding of the most important neuropeptides. The text also contains a complete and up-to-date reference/reading list.
