Neural Grafting

Neural Grafting
Author: United States. Congress. Office of Technology Assessment
Publisher:
Total Pages: 208
Release: 1990
Genre: Central nervous system
ISBN:

How to Improve the Results of Peripheral Nerve Surgery

How to Improve the Results of Peripheral Nerve Surgery
Author: Hanno Millesi
Publisher: Springer Science & Business Media
Total Pages: 166
Release: 2007-12-31
Genre: Medical
ISBN: 3211729585

All over the world research is going on to improve the outcome of the treatment of peripheral nerve lesions. Yet, there exist many questions, such as: Is the autologeous nerve grafting still the golden standard in bridging defects? Have alternative techniques to overcome defects reached a level to replace autografting? What can be expected from end to side coaptation? The contributions in this book give answers to all of these questions.

Neural Transplantation, CNS Neuronal Injury, and Regeneration

Neural Transplantation, CNS Neuronal Injury, and Regeneration
Author: Joe Marwah
Publisher: CRC Press
Total Pages: 304
Release: 1994-02-23
Genre: Medical
ISBN: 9780849386831

This unique reference presents studies from leading laboratories that are studying the effects of CNS transplants on neuronal plasticity and recovery of function after CNS injury. Topics covered include tropic influences, reinnervation patterns, and prevention of cell death that range from pre-clinical models of Parkinson's disease in primates to studies of restoration of circadian rhythms in rats. Techniques of neurotransplantation are presented, including current limitations and future projections of advancement.

Functional Neural Transplantation IV

Functional Neural Transplantation IV
Author:
Publisher: Academic Press
Total Pages: 384
Release: 2017-05-25
Genre: Medical
ISBN: 012811813X

Functional Neural Transplantation IV: Translation to Clinical Application, Volume 230 provides the current status of cell transplantation in the nervous system, with a focus on the conditions for achieving structural repair and functional recovery after brain damage or in neurodegenerative disease. New to this release are chapters that delve into the Mechanisms and Use of Neural Transplants for Brain Repair, Reprogramming of Somatic Cells: iPS and iN Cells, Brain Repair from Intrinsic Cell Sources: Turning Reactive Glia into Neurons, and Ex Vivo Gene Therapy for the Treatment of Neurological Disorders, Preparation, Characterization and Banking of Clinical-grade Cells for Neural Transplantation. As the fourth in a periodic series of updates at 5-7 year intervals, this volume highlights recent developments related to the application of advances in cellular and molecular science, providing an understanding of the fundamental principles of neuroplasticity and regeneration in the brain and spinal cord, and also addressing the topic of the power of pluripotent stem cells to generate new sources of precisely specified neurons for utilization in brain repair. - Comprehensive set of critical reviews covering the field - Presents state-of-the-art topics in science and translational medicine - Written by international leaders in the field of neural transplantation

Neural Transplantation in Neurodegenerative Disease

Neural Transplantation in Neurodegenerative Disease
Author: Derek J. Chadwick
Publisher: John Wiley & Sons
Total Pages: 334
Release: 2003-10-31
Genre: Medical
ISBN: 0470870826

The field of neural transplantation is at a crucial stage, with important clinical trials on transplantation in patients with Parkinson's disease nearing completion and novel, alternative approaches to fetal transplantation being developed. This timely book brings together leading neuroscientists, clinicians, and cell and developmental biologists to discuss the use of neural transplants in neurodegenerative disorders, such as Parkinson's disease, Huntington's chorea, amyotrophic lateral sclerosis, multiple sclerosis and spinal cord injury. There is also extensive coverage of the potential alternatives to freshly derived fetal tissue as the source of transplants, for example xenografts, encapsulated cells and immortalized stem cells. With authoritative contributions and lively discussion sections, this book presents much new and exciting work in this field and identifies promising new research directions.

Neural Repair, Transplantation, and Rehabilitation

Neural Repair, Transplantation, and Rehabilitation
Author: Roger A. Barker
Publisher: Psychology Press
Total Pages: 356
Release: 1999
Genre: Medical
ISBN: 9780863776281

This book begins with a synopsis of experimental work underlying degeneration and recovery in the nervous system, which is then discussed in the context of strategies to repair the central nervous system (CNS) and peripheral nervous system (PNS). The major part of the book is given over to the approach involving the use of transplanted tissues to replace and restore disrupted neural networks. This experimental work has formed the basis for the emerging clinical trials employing neural grafts for diseases such as Parkinson's and Huntington's, which are discussed in detail. The book then goes on to discuss newer cellular strategies involving the manipulation of neural cells both in culture and genetically, an approach that may ultimately be employed in the clinical situation. Neural Repair, Transplantation and Rehabilitation is unique in bridging the gap from experimental studies to clinical trials, whilst also providing the non-specialist with a background in rehabilitation strategies as well as basic neuroscience. It is recommended for all those involved in the management of patients with degenerative and traumatic injuries to the nervous system.

Neuroproteomics

Neuroproteomics
Author: Oscar Alzate
Publisher: CRC Press
Total Pages: 356
Release: 2009-10-26
Genre: Medical
ISBN: 1420076264

In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we beg

Neuronal Grafting and Alzheimer’s Disease

Neuronal Grafting and Alzheimer’s Disease
Author: F.H. Gage
Publisher: Springer Science & Business Media
Total Pages: 214
Release: 2013-03-08
Genre: Medical
ISBN: 3642483690

Alzheimer's disease is one of the major scientific, medical and social challenges of our time. This book (the third volume of proceedings of the Colloques Médecine et Recherche of the Fondation Ipsen pour la Recherche Thérapeutique) is dedicated to neuronal grafting and Alzheimer's disease. The wealth of basic information presented testifies to the progress that has been achieved in intracerebral grafting and to the utility of intracerebral grafting as a tool for the understanding of brain development, adult neuronal plasticity and age-related pathology. An answer to the question, whether neuronal grafting will be useful as a therapy for Alzheimer's disease, must wait for a better understanding of the disease and the identification of animal models that can be used to test potential therapies. Meanwhile, the tool of intracerebral grafting may, in the future, be used to address the pathophysiology of Alzheimer's disease.