Nephropathy In Type 2 Diabetes
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| Author | : Z.-H. Liui |
| Publisher | : Karger Medical and Scientific Publishers |
| Total Pages | : 274 |
| Release | : 2014-05-16 |
| Genre | : Science |
| ISBN | : 3318026514 |
The podocyte is a key cell that forms the last barrier of the kidney filtration unit. One of the most exciting developments in the field of nephrology in the last decade has been the elucidation of its biology and its role in the pathophysiology of inherited and acquired glomerular disease, termed podocytopathy. In this publication, world-renowned experts summarize the most recent findings and advances in the field: they describe the unique biological features and injury mechanisms of the podocyte, novel techniques used in their study, and diagnosis and potential therapeutic approaches to glomerular diseases. Due to its broad scope, this publication is of great value not only for clinical nephrologists and researchers, but also for students, residents, fellows, and postdocs.
| Author | : Francisco Bandeira |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 550 |
| Release | : 2013-10-26 |
| Genre | : Medical |
| ISBN | : 146148684X |
Endocrinology, and diabetes care in particular, is a dynamic field where clinicians must translate new evidence into clinical practice at a rapid pace. Designed in an engaging, case-based format, Endocrinology and Diabetes: A Problem Oriented Approach offers a wide range of thought-provoking case studies that reflect contemporary, challenging, hands-on clinical care. Further, by providing a list of specific clinical problems, this format offers the reader a more convenient and pointed way to solve precise clinical problems in a timely manner. Developed by a renowned, international group of experts, this comprehensive title covers the most common clinical problems in endocrinology and diabetes and should be of great interest to endocrinologists, diabetologists, internal medicine physicians, family physicians, fellows, and residents.
| Author | : Pedro Cortes |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 553 |
| Release | : 2007-11-06 |
| Genre | : Medical |
| ISBN | : 1597451533 |
A comprehensive and authoritative survey of recent findings, ideas, and hypotheses about the causes and treatment of diabetic nephropathy. The authors cover both the basic pathogenic mechanisms of the disease, as well as many of its clinical aspects of identification, management, and new therapeutic approaches. Highlights include an entire section devoted to novel approaches to studying diabetic nephropathy with the most advanced molecular techniques, and complete descriptions of the most up-to-date views on the diagnosis and treatment of the disease. The Diabetic Kidney offers both researchers and practicing clinicians a clear understanding of the of the progress that has been made regarding the pathogenesis of diabetic nephropathy and of the therapeutic interventions needed to prevent its development or treat it.
| Author | : Joris J. Roelofs |
| Publisher | : Springer |
| Total Pages | : 540 |
| Release | : 2018-10-29 |
| Genre | : Medical |
| ISBN | : 3319935216 |
This book provides an overview of the most up-to-date research on diabetic nephropathy and the current understanding of its pathogenesis, clinical features and socio-economic developments. Written by leading experts in the field, it provides a comprehensive synthesis of clinical and pathophysiological aspects from a mechanism-based point of view, and reviews evidence-based treatment modalities for the prevention and management of diabetic nephropathy. In addition, closely related areas such as diabesity, diabetic eye disease and macrovascular involvement in diabetes are addressed. Diabetic Nephropathy will be of interest for nephrologists, diabetologists, internists, transplant physicians, public health professionals, basic scientists, geneticists, epidemiologists, pathologists, and molecular and cell biologists working in the field of diabetes and its complications.
| Author | : Kar Neng Lai |
| Publisher | : Karger Medical and Scientific Publishers |
| Total Pages | : 288 |
| Release | : 2011 |
| Genre | : Medical |
| ISBN | : 3805597428 |
A comprehensive update on clinical and basic aspects of diabetic nephropathy Caused by an epidemic increase in obesity and diabetes and metabolic syndromes, diabetic nephropathy has become a leading cause of end-stage renal disease in many developed countries. The publication at hand provides a concise overview of the current state of clinical and basic research in the field. It starts with a summary of the epidemiology and genetics of diabetic nephropathy in different ethnic groups, followed by a review of its clinical manifestation, the link with the metabolic syndrome and obesity, and the pathology of diabetic nephropathy. Building on this basis, the latest findings on pathogenetic, epigenetic and inflammatory mechanisms are presented. The publication also looks at advances in the areas of tubulopathy and the kallikrein-kinin system as well as at the latest animal models and the role of lipoproteins and proteomics. This is followed by a discussion of promising therapeutic approaches such as experimental anti-fibrotic strategies, stem cell therapy and pancreatic transplantation; expert reviews on the emerging entity of new onset diabetes after transplantation and the preventive strategies for diabetic nephropathy conclude the material presented. Written by a panel of leading international experts, this book is highly recommended for nephrologists, diabetologists, internist, transplant physicians, scientists, geneticists, epidemiologists and stem cell biologists working in the field of diabetic nephropathy.
| Author | : Shamim I. Ahmad |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 515 |
| Release | : 2013-04-12 |
| Genre | : Medical |
| ISBN | : 1461454417 |
Diabetes is a complex disease and is also one of the most common. It is very difficult to reach an accurate estimate for the global prevalence of diabetes since the standards and methods of data collection vary widely in different parts of the world. In addition, many potential sufferers are not included in the count because according to an estimate about 50% of cases remain undiagnosed for up to 10 years. However, according to an estimate for 2010, globally, there are about 285 million people (amounting to 6.4% of the adult population) suffering from this disease. This number is estimated to increase to 439 million by 2030 if no cure is found. The general increase in life expectancy, leading to an ageing population, and the global rise in obesity are two main reasons for the increase. With the basic platform set, Editor presents his views and advice to the readers, especially to diabetic patients suffering from T2DM, on the basis of his observations and information collected from other diabetics.
| Author | : Luigi Gnudi |
| Publisher | : Humana |
| Total Pages | : 0 |
| Release | : 2019-11-08 |
| Genre | : Science |
| ISBN | : 9781493998401 |
This book provides a toolkit of novel research approaches for investigators to study diabetic nephropathy, including critical experimental models from the fly to the fish, cells in culture, and in vivo mammalian approaches. The collection also explores powerful techniques to image the kidney, such as traditional histological techniques as well as electron, confocal, and two-photon microscopy, pathophysiology of the diabetic kidney, and gene editing and regenerative medicine. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Diabetic Nephropathy: Methods and Protocols seeks to foster new research directions and inspire ideas to enhance our understanding of diabetic nephropathy and to develop treatments for this condition.
| Author | : Agnes B. Fogo |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 223 |
| Release | : 2013-10-24 |
| Genre | : Medical |
| ISBN | : 3642390803 |
Fundamentals of Renal Pathology is a compact and up-to-date resource on the basics of renal pathology that will be of particular value for residents and fellows in training in renal pathology, general pathology, and nephrology, but will also serve as a handy reference for the more experienced. This second, revised and updated edition of the book offers an integrated approach based on contributions from established experts in the field. Key diseases are discussed within the context of clinical presentations, with the emphasis on clinicopathological correlation and differential diagnosis. Topics discussed include glomerular diseases with nephrotic or nephritic syndrome presentations; systemic and vascular diseases affecting the kidney, including diseases affecting the renal transplant; tubulointerstitial diseases; and plasma cell dyscrasias and associated diseases. Well-chosen color illustrations and electron micrographs enhance and complement the text.
| Author | : V. Jörgens |
| Publisher | : Karger Medical and Scientific Publishers |
| Total Pages | : 318 |
| Release | : 2020-08-06 |
| Genre | : Medical |
| ISBN | : 3318067342 |
A history of diabetology told by renowned contributors, many have themselves already become a part of diabetes history. A must-have for every diabetologist! Diabetologists, diabetes educators, and many interested readers will appreciate this book. What is more, countless celebrations are planned for the 100th anniversary of the discovery of insulin: this book provides numerous illustrations, accounts of personal experiences, and critical remarks on the history of diabetology – in addition to the history of insulin. It spans an arc from antiquity to the work of Claude Bernard, Paul Langerhans, Josef von Mering, Apollinaire Bouchardat, Oskar Minkowski, E.P. Joslin, and F.M. Allen. The history of insulin is presented from the perspective of diabetologists from Scotland, Spain, Germany, and Poland. The history of oral antidiabetics is told by Harald Lebovitz, and the chapter about glitazones by Edwin Gale reads like a spy novel! Pierre Lefèbvre describes the work of the diabetologist Jean Pirart and the history of glucagon. Sir George Alberti has provided a chapter about the therapy of ketoacidosis, to which he himself made groundbreaking contributions. Nephropathy is presented by Hans-Henrik Parving, and Eva Kohner, Ronald Klein and Barbara E.K. Klein have contributed a chapter on retinopathy. Other contemporary topics such diabetes in pregnancy, diabetes technology, psychosocial aspects of diabetes, and the history of the EASD and ADA are also included in this book.
| Author | : Eberhard Ritz |
| Publisher | : |
| Total Pages | : 328 |
| Release | : 1999 |
| Genre | : Medical |
| ISBN | : |
Clinical nephrology is confronted with an emerging medical catastrophe of international proportions: endstage renal failure in patients with type 2 diabetes. From a number of recent studies it has become apparent that nephropathy in type 2 diabetes is a preventable condition, at least in principle. It is for this reason that it appeared timely to summarize the current state of knowledge concerning nephropathy in type 2 diabetes, giving an update on the predisposing factors on which interventions are of proven benefit and on the accepted standards of management of such patients. This concise monograph is addressed not only to nephrologists, but also to diabetologists and general practitioners. It is hoped that it will help to improve clinical outcomes in the future.
