This publication is intended to provide comprehensive yet concise information on indications, doses, preparation, administration, and adverse reactions of drugs in use during the neonatal period. There is particular emphasis on preparation and administration by neonatal nurses. Compatibility of intravenous medications with concurrent other fluids or medications are thoroughly addressed. The routes for the administration of various medications are delineated. The most recognised adverse effects of various medications are flagged up, but the lists are by no means all-inclusive. It is advisable to consult up to date periodically if reactions or side effects outside the specific monograph texts are encountered. Furthermore, the publication focuses on known contraindications, precautions, and practical advice. A considerable effort has been exercised to ensure the doses, calculations, with or without dilutions, are accurate. However, further confirmation by the nursing and medical personnel is advised prior to the first use of each individual monograph. Feedback and suggestions are appreciated and can be sent to [email protected]. It is acknowledged that many neonatal units prefer to custom their own dilutions, concentrations, and infusion times. Nevertheless, the information in the various monographs is counterchecked with the practice of various well recognised international neonatal units. The use of computerised programmed infusion pumps is ideal but is not available in most nurseries. The latest edition of the British National Formulary for Children (BNFc, September 2022-September 2023, Last updated 14 December 2022) is used as the primary source for many medications' doses, side effects and contraindications. Various other useful references are utilised and are listed on the last page. The intention is to update the information on the web version of this publication on a regular basis. The publication is written bearing in mind the wide variations in the skill mix of neonatal practitioners, both nurses and doctors. Likewise, the challenging circumstances in developing countries are taken into consideration. Many of the stated calculations, methods of infusions or administration and monitoring requirements may appear too extensive and long winded. However, this is intended to be excessively simple to take some pressure off the shoulders of busy doctors and nurses. Printing and laminating individual monographs for the commonly used medications extracted from this publication is highly recommended. It would provide a quick and easily accessible source when every minute counts. The publication reflects the author's own acceptable and safe practices and advice. It is written with the intention of facilitating the delivery of care to the most vulnerable newborn. However, the responsibility of correct prescriptions, calculations and administration falls on the individual practitioners. The clinical pharmacist of the hospital may be requested to endorse individual drug monographs or the whole publication before the neonatal unit adopts it. It is a legal requirement to advise users of the information provided within this publication that the editor and publisher are not responsible for any errors or omissions and/or any consequences arising from the use of the information in this book.