Fashion is part of a paradigm shift transforming its manufacturing models. Beauty, creativity, elegance and originality, the main values of fashion, have long been considered as unrelated or antithetical to sustainability and environmental protection. The border that used to separate them has been crossed. The paradigm shift occurred in the first decade of the new century involving negligible vibrations, which in the last few years, have quickly turned into a big wave pushing a large part of the industry, still chaotically and contradictorily, including leading brands that now consider commitment to sustainability as a distinctive feature of their identity. Materials are therefore back in the spotlight, being the basis for designers to express their creativity, which is still the main engine of fashion. Materials allow reviewing the importance of supply chains, from yarns to fabrics, from materials-enriching finishing to manufacturing of garments and accessories. Neo-Materials in Circular Economy - Fashion is an updated overview of changes occurring in one of the most relevant industries of global economy. Starting from the analysis of materials, divided into three large areas (renewable, non-renewable and recycled), the book examines use of water and chemicals and eventually provides an overview of initiatives on sustainability implemented by small and big brands. Complemented by interviews with some of the most innovative players of the industry, this book is going to become a benchmark on this issue, which is undeniably crucial for fashion.