Scientific Frontiers in Developmental Toxicology and Risk Assessment

Scientific Frontiers in Developmental Toxicology and Risk Assessment
Author: National Research Council
Publisher: National Academies Press
Total Pages: 348
Release: 2000-12-21
Genre: Nature
ISBN: 0309070864

Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.

C. Elegans II

C. Elegans II
Author: Donald L. Riddle
Publisher: Firefly Books
Total Pages: 1252
Release: 1997
Genre: Medical
ISBN: 9780879695323

Defines the current status of research in the genetics, anatomy, and development of the nematode C. elegans, providing a detailed molecular explanation of how development is regulated and how the nervous system specifies varied aspects of behavior. Contains sections on the genome, development, neural networks and behavior, and life history and evolution. Appendices offer genetic nomenclature, a list of laboratory strain and allele designations, skeleton genetic maps, a list of characterized genes, a table of neurotransmitter assignments for specific neurons, and information on codon usage. Includes bandw photos. For researchers in worm studies, as well as the wider community of researchers in cell and molecular biology. Annotation copyrighted by Book News, Inc., Portland, OR

Nematode Behaviour

Nematode Behaviour
Author: Randy Gaugler
Publisher: CABI
Total Pages: 450
Release: 2004
Genre: Reference
ISBN: 9780851999555

Nematode worms are among the most ubiquitous organisms on earth. They include free-living forms as well as parasites of plants, insects, humans and other animals. In recent years there has been an explosion of interest in nematode biology, including the area of nematode behaviour. The latter has, however, until now, not been synthesized into a single comprehensive volume.Nematode Behaviour seeks to redress this imbalance by providing the first comprehensive review of current knowledge of the behaviour of nematodes. Key topics including locomotion and orientation, feeding and reproductive behaviour, and biotic and abiotic interactions are reviewed by leading authorities from the USA, UK, India and New Zealand.

Behavioral and Department Models

Behavioral and Department Models
Author: Bert Zuckerman
Publisher: Elsevier
Total Pages: 327
Release: 2012-12-02
Genre: Science
ISBN: 0323155804

Nematodes as Biological Models is two-volume treatise that provides a comprehensive reference source for research, in which free-living nematodes have been used to examine fundamental processes in genetics, development, nutrition, toxicology, pharmacology, and gerontology. The text emphasizes the use of Caenorhabditis elegans as a model in a variety of biological studies and also includes description of important studies utilizing other free-living nematodes as models. Volume 1: Behavioral and Developmental Models covers cell lineages, muscle development, behavior, the nervous system, control mechanisms, and genetics, with the major emphasis on C. elegans. Significant contributions derived primarily from studies on the parasitic nematode Ascaris and the free-living nematode Panagrellus are also considered. The second volume includes discussions on free-living nematodes as biological models for pharmacological and toxicant testing, and for studies on gerontology and nutrition. Several chapters in this volume also cover nematode physiology and morphology, which readers will find useful in understanding the subject matter. The book is a masterful reference for students and lecturers in parasitology, zoology, physiology, and other related biological courses. Researchers and extended workers on nematology and related disciplines will also find this book invaluable.

C. Elegans Atlas

C. Elegans Atlas
Author: David H. Hall
Publisher: CSHL Press
Total Pages: 353
Release: 2008
Genre: Caenorhabditis elegans
ISBN: 0879697156

Derived from the acclaimed online “WormAtlas,†C. elegansAtlas is a large-format, full-color atlas of the hermaphroditic form of the model organism C. elegans, known affectionately as “the worm†by workers in the field. Prepared by the editors of the WormAtlas Consortium, David H. Hall and Zeynep F. Altun, this book combines explanatory text with copious, labeled, color illustrations and electron micrographs of the major body systems of C. elegans. Also included are electron microscopy cross sections of the worm. This laboratory reference is essential for the working worm biologist, at the bench and at the microscope, and provides a superb companion to the C. elegansII monograph. It is also a valuable tool for investigators in the fields of developmental biology, neurobiology, reproductive biology, gene expression, and molecular biology.

Reviews of Environmental Contamination and Toxicology Volume 237

Reviews of Environmental Contamination and Toxicology Volume 237
Author: W.P. de Voogt
Publisher: Springer
Total Pages: 204
Release: 2015-11-27
Genre: Science
ISBN: 3319235737

Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications.