Natural Poisons And Venoms
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Author | : Ronald Jenner |
Publisher | : Smithsonian Institution |
Total Pages | : 207 |
Release | : 2017-10-17 |
Genre | : Nature |
ISBN | : 1588344541 |
Venom brings readers face to face with some of the most dangerous creatures on the planet, including jellyfish, snakes, and wasps, as it uncovers the story of venom. The book explores how venom is used for predation, defense, competition, and communication by an incredible diversity of species. It examines the unique methods that these species have evolved to create and deliver their deadly toxins. The book traces venom back to its origin in early jellyfish and sea anemones, and reveals how venoms have evolved dozens of times independently all across the animal kingdom since that time. And finally, it examines the relationships between these dangerous creatures and humans. Humans have not only learned to live with them, but also to benefit from them: scientists increasingly are harnessing the power of venom to create new drugs, treatments, and anti-venoms.
Author | : Eberhard Teuscher |
Publisher | : Walter de Gruyter GmbH & Co KG |
Total Pages | : 350 |
Release | : 2023-06-06 |
Genre | : Science |
ISBN | : 3110724731 |
Biogenic toxins are fascinating natural products characterized by an enormous diversity of chemical structures and pharmacological activities. They not only pose hazards to humans and animals, but they are important components in the interplay of substances and living beings in nature and, moreover, important sources for new drugs. The present book is the first volume of the 5-volume series "Natural Poisons and Venoms". Volumes 1-3 cover poisons produced by plants, volume 4 summarizes poisons and venoms of animals and volume 5 deal with poisons of fungi, cyanobacteria, and other microorganisms. This volume starts with a fundamental chapter on history, chemistry and pharmacology of natural toxins, importance of the toxins for their producer, potential danger for humans and animals, and general aspects of toxicology including notes for first aid and proposals for clinical measures. The following chapters focus on the poisonous representatives of terpenes and the related steroids. The reader will be informed about the botany and occurrence of plants producing these toxins, the chemistry, the biogenesis and the pharmacology of the toxins, possible causes of poisonings, precautions to avoid poisonings, symptoms of poisonings of humans and animals, proposals for treatment measures and the possible usefulness, in the past, in present and in the future, of these toxins, especially for the development of new medicines. Numerous images of plants and chemical structural formulas complete the book. Extensive lists of literature references are given. The handbook is intended for physicians, veterinarians, pharmacists, chemists, biochemists, food chemists and biologists, for the students in the relevant fields, and also for interested laymen. You will be informed about all aspects of natural toxins based on the latest knowledge.
Author | : Glenn King |
Publisher | : Royal Society of Chemistry |
Total Pages | : 338 |
Release | : 2015-02-11 |
Genre | : Science |
ISBN | : 1849736634 |
This unique book will provide an up to date and comprehensive account of the potential of peptides and proteins from animal venoms as possible therapeutics. The pharmaceutical industry has become increasingly interested in biologics from animal venoms as a potential source for therapeutic agents in recent years, with a particularly emphasis on peptides. To date six drugs derived from venom peptides or proteins have been approved by the FDA, with nine further agents currently being investigated in clinical trials. In addition to these drugs in approved or advanced stages of development, many more peptides and proteins are being studied in varying stages of preclinical development. Topics covered include chemistry and structural biology of animal venoms, proteomic and transcriptomic approaches to drug discovery, bioassays, high-throughput screens and target identification, and reptile, scorpion, spider and cone snail venoms as a platform for drug development. Case studies are used to illustrate methods and successes and highlight issues surrounding administration and other important lessons that have been learnt from the development of approved therapeutics based on venoms. The first text to focus on this fascinating area and bridging an important gap, this book will provide the reader with essential and current knowledge on this fast-developing area. Venoms to Drugs will find wide readership with researchers working in academia and industry working in all medicinal and pharmaceutical areas.
Author | : Jan-Peter Hildebrandt |
Publisher | : Walter de Gruyter GmbH & Co KG |
Total Pages | : 547 |
Release | : 2023-07-04 |
Genre | : Science |
ISBN | : 3110728621 |
This book series is based on the book "Biogene Gifte", 3. Edition, published 2010 by Wissenschaftliche Verlagsgesellschaft Stuttgart in German language. Because of the enormous increase in knowledge in the field of natural poisons and venoms the topic is now covered in 5 volumes in English language. The focus of this volume is on the toxic ingredients of animal poisons and venoms, their chemical structures, their effects and modes of actions in target organisms, and on the biology of poisonous or venomous animals. It highlights the symptoms of poisoning or envenoming in humans or animals, cite case reports were available, and gives hints on poisoning prevention and on potential treatments.
Author | : Christie Wilcox |
Publisher | : Macmillan + ORM |
Total Pages | : 219 |
Release | : 2016-08-09 |
Genre | : Science |
ISBN | : 0374712212 |
A thrilling tale of encounters with nature’s masters of biochemistry From the coasts of Indonesia to the rainforests of Peru, venomous animals are everywhere—and often lurking out of sight. Humans have feared them for centuries, long considering them the assassins and pariahs of the natural world. Now, in Venomous, the biologist Christie Wilcox investigates and illuminates the animals of our nightmares, arguing that they hold the keys to a deeper understanding of evolution, adaptation, and immunity. She reveals just how venoms function and what they do to the human body. With Wilcox as our guide, we encounter a jellyfish with tentacles covered in stinging cells that can kill humans in minutes; a two-inch caterpillar with toxic bristles that trigger hemorrhaging; and a stunning blue-ringed octopus capable of inducing total paralysis. How do these animals go about their deadly work? How did they develop such intricate, potent toxins? Wilcox takes us around the world and down to the cellular level to find out. Throughout her journey, Wilcox meets the intrepid scientists who risk their lives studying these lethal beasts, as well as “self-immunizers” who deliberately expose themselves to snakebites. Along the way, she puts her own life on the line, narrowly avoiding being envenomated herself. Drawing on her own research, Wilcox explains how venom scientists are untangling the mechanisms of some of our most devastating diseases, and reports on pharmacologists who are already exploiting venoms to produce lifesaving drugs. We discover that venomous creatures are in fact keystone species that play crucial roles in their ecosystems and ours—and for this alone, they ought to be protected and appreciated. Thrilling and surprising at every turn, Venomous will change everything you thought you knew about the planet’s most dangerous animals.
Author | : Dietrich Frohne |
Publisher | : Timber Press (OR) |
Total Pages | : 488 |
Release | : 2005-09-14 |
Genre | : Gardening |
ISBN | : |
"The majority covered here originate in temperate zones, and the text comprehensively identifies potentially dangerous plants, their distribution, level of toxicity, symptoms of poisoning and suggested treatment. Illustrations range from actual size colour and black/white photos to enlarged representations of microscopically recognizable features in fruits and leaves." --Cover.
Author | : Alan Kolok |
Publisher | : Island Press |
Total Pages | : 224 |
Release | : 2016-05-05 |
Genre | : Health & Fitness |
ISBN | : 1610913825 |
Modern Poisons bridges the gap between traditional toxicology textbooks and journal articles on cutting-edge science. This accessible book explains basic principles in plain language while illuminating the most important issues in contemporary toxicology. Kolok begins by exploring age-old precepts such as the dose-response relationship and goes on to show exactly how chemicals enter the body and elicit their toxic effect. Kolok then traces toxicology's development, from studies of endocrine-disrupting chemicals in toiletries to the emerging science on prions and epigenetics. Whether studying toxicology itself, public health, or environmental science, readers will develop a core understanding of--and curiosity about--this fast-changing field.
Author | : Eberhard Teuscher |
Publisher | : Walter de Gruyter GmbH & Co KG |
Total Pages | : 485 |
Release | : 2023-06-06 |
Genre | : Science |
ISBN | : 3110724863 |
Biogenic toxins are fascinating natural products characterized by an enormous diversity of chemical structures and pharmacological activities. They not only pose hazards to humans and animals, but they are important components in the interplay of substances and living beings in nature and, moreover, important sources for new drugs. The present book is the first volume of the 5-volume series "Natural Poisons and Venoms". Volumes 1-3 cover poisons produced by plants, volume 4 summarizes poisons and venoms of animals and volume 5 deal with poisons of fungi, cyanobacteria, and other microorganisms. This volume starts with a fundamental chapter on history, chemistry and pharmacology of natural toxins, importance of the toxins for their producer, potential danger for humans and animals, and general aspects of toxicology including notes for first aid and proposals for clinical measures. The following chapters focus on the poisonous representatives of terpenes and the related steroids. The reader will be informed about the botany and occurrence of plants producing these toxins, the chemistry, the biogenesis and the pharmacology of the toxins, possible causes of poisonings, precautions to avoid poisonings, symptoms of poisonings of humans and animals, proposals for treatment measures and the possible usefulness, in the past, in present and in the future, of these toxins, especially for the development of new medicines. Numerous images of plants and chemical structural formulas complete the book. Extensive lists of literature references are given. The handbook is intended for physicians, veterinarians, pharmacists, chemists, biochemists, food chemists and biologists, for the students in the relevant fields, and also for interested laymen. You will be informed about all aspects of natural toxins based on the latest knowledge.
Author | : Findlay E. Russell |
Publisher | : |
Total Pages | : 462 |
Release | : 1967 |
Genre | : Toxins |
ISBN | : |
Author | : P. Gopalakrishnakone |
Publisher | : Springer |
Total Pages | : 0 |
Release | : 2016-05-10 |
Genre | : Medical |
ISBN | : 9789400763883 |
In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.