Bridges to Independence

Bridges to Independence
Author: National Research Council
Publisher: National Academies Press
Total Pages: 173
Release: 2005-08-26
Genre: Medical
ISBN: 030909626X

A rising median age at which PhD's receive their first research grant from the National Institutes of Health (NIH) is among the factors forcing academic biomedical researchers to spend longer periods of time before they can set their own research directions and establish there independence. The fear that promising prospective scientists will choose other career paths has raised concerns about the future of biomedical research in the United States. At the request of NIH, the National Academies conducted a study on ways to address these issues. The report recommends that NIH make fostering independence of biomedical researchers an agencywide goal, and that it take steps to provide postdocs and early-career investigators with more financial support for their own research, improve postdoc mentoring and establish programs for new investigators and staff scientists among other mechanisms.

The CTSA Program at NIH

The CTSA Program at NIH
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 179
Release: 2013-10-09
Genre: Medical
ISBN: 0309284740

In 2006 the National Institutes of Health (NIH) established the Clinical and Translational Science Awards (CTSA) Program, recognizing the need for a new impetus to encourage clinical and translational research. At the time it was very difficult to translate basic and clinical research into clinical and community practice; making it difficult for individual patients and communities to receive its benefits. Since its creation the CTSA Program has expanded, with 61 sites spread across the nation's academic health centers and other institutions, hoping to provide catalysts and test beds for policies and practices that can benefit clinical and translation research organizations throughout the country. The NIH contracted with the Institute of Medicine (IOM) in 2012 to conduct a study to assess and provide recommendations on appropriateness of the CTSA Program's mission and strategic goals and whether changes were needed. The study was also address the implementation of the program by the National Center for Advancing Translational Sciences (NCATS) while exploring the CTSA's contributions in the acceleration of the development of new therapeutics. A 13-member committee was established to head this task; the committee had collective expertise in community outreach and engagement, public health and health policy, bioethics, education and training, pharmaceutical research and development, program evaluation, clinical and biomedical research, and child health research. The CTSA Program at NIH: Opportunities for Advancing Clinical and Translational Research is the result of investigations into previous program evaluations and assessments, open-session meetings and conference class, and the review of scientific literature. Overall, the committee believes that the CTSA Program is significant to the advancement of clinical and translational research through its contributions. The Program would benefit from a variety of revisions, however, to make it more efficient and effective.

Advancing the Nation's Health Needs

Advancing the Nation's Health Needs
Author: National Research Council
Publisher: National Academies Press
Total Pages: 187
Release: 2005-08-13
Genre: Medical
ISBN: 0309094275

This report is the twelfth assessment of the National Institutes of Health National Research Service Awards program. The research training needs of the country in basic biomedical, clinical, and behavioral and social sciences are considered. Also included are the training needs of oral health, nursing, and health services research. The report has been broadly constructed to take into account the rapidly evolving national and international health care needs. The past and present are analyzed, and predictions with regard to future needs are presented.

How to Write a Successful Research Grant Application

How to Write a Successful Research Grant Application
Author: Willo Pequegnat
Publisher: Springer Science & Business Media
Total Pages: 248
Release: 2013-03-09
Genre: Social Science
ISBN: 1475723938

The Department of Health and Human Services has identified Acquired Immunodeficiency Syndrome (AIDS) as the foremost public health problem in the United States. The Centers for Disease Control (CDC) report that, as of December 31, 1994, there were 441,528 documented cases of AIDS in this country, and the number is increasing. AIDS is an illness characterized by a defect in natural immunity against disease. Many more individuals are known to be infected with Human Immunodeficiency Virus (HIV) but do not have symptoms or the defming characteristics of AIDS. The incubation period for AIDS may range from 1 to 10 or more years in adults and 6 months to several years in children. Infected persons appear to be capable of transmitting infection indefinitely, even if they remain asymptomatic. In order to increase the number of minority investigators conducting research on HIV infection and 1 AIDS, NIMH conducted a 3h-day technical workshop for minority investigators on July 24-27. 1990, in Fairlakes, Virginia. University-based research programs were asked to nominate investigators who were selected on the basis of a referred 1 0-page prospectus for a proposed research project. This procedure was used because NIMH wanted to be sure that the prospective investigators were established in a research environment that would pr

NCI Grants Awarded

NCI Grants Awarded
Author: National Cancer Institute (U.S.). Division of Cancer Research Resources and Centers. Grants Financial and Data Analysis Branch
Publisher:
Total Pages: 284
Release: 1979
Genre: Cancer
ISBN:

Principles and Practice of Clinical Research

Principles and Practice of Clinical Research
Author: John I. Gallin
Publisher: Elsevier
Total Pages: 447
Release: 2011-04-28
Genre: Science
ISBN: 0080489567

The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers.*Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical Research *Addresses the vast opportunities for translation of basic science observations to the bedside through clinical research*Delves into data management and addresses how to collect data and use it for discovery*Contains valuable, up-to-date information on how to obtain funding from the federal government

Strategies to Leverage Research Funding

Strategies to Leverage Research Funding
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 193
Release: 2004-11-27
Genre: Medical
ISBN: 0309092779

Since 1992 the Department of Defense (DOD), through the U.S. Army Medical Research and Material Command, has received congressionally earmarked appropriations for programs of biomedical research on prostate, breast, and ovarian cancer; neurofibromatosis; tuberous sclerosis; and other health problems. Appropriations for these Congressionally Directed Medical Research Programs are used to support peer reviewed extramural research project, training, and infrastructure grants. Congress has become concerned about funding increases for these programs given current demands on the military budget. At the request of Congress, the Institute of Medicine (IOM) examined possibilities of augmenting program funding from alternative sources. The resulting IOM book, Strategies to Leverage Research Funding: Guiding DOD's Peer Reviewed Medical Research Programs, focuses on nonfederal and private sector contributions that could extend the appropriated funds without biasing the peer review project selection process.

A Practical Guide to Writing a Ruth L. Kirschstein NRSA Grant

A Practical Guide to Writing a Ruth L. Kirschstein NRSA Grant
Author: Andrew D. Hollenbach
Publisher: Academic Press
Total Pages: 123
Release: 2013-09-20
Genre: Medical
ISBN: 0124202365

A Practical Guide to Writing a Ruth L. Kirschstein NRSA Grant provides F-Series grant applicants and mentors with insider knowledge on the process by which these grants are reviewed, the biases that contribute to the reviews, the extent of information required in an NRSA training grant, a deeper understanding of the exact purpose of each section of the application, and key suggestions and recommendations on how to best construct each and every section of the application. A Practical Guide to Writing a Ruth L. Kirschstein NRSA Grant is a solid resource for trainees and their mentors to use as a guide when constructing F30, F31, and F32 grant applications. - Covers F30, F31, and F32 grant applications - Detailed overview of the review process - Key suggestions on how to best construct each section of the application - Includes a checklist of required items