Nanoparticles in the Lung

Nanoparticles in the Lung
Author: Akira Tsuda
Publisher: CRC Press
Total Pages: 403
Release: 2014-12-19
Genre: Medical
ISBN: 1439892806

Nanoparticles have a physical dimension comparable to the size of molecular structures on the cell surface. Therefore, nanoparticles, compared to larger (e.g., micrometer) particles, are considered to behave differently when they interact with cells. Nanoparticles in the Lung: Environmental Exposure and Drug Delivery provides a better understanding

Nanoparticles in the Lung

Nanoparticles in the Lung
Author: Akira Tsuda
Publisher: CRC Press
Total Pages: 404
Release: 2020-09-30
Genre:
ISBN: 9781138749207

Nanoparticles have a physical dimension comparable to the size of molecular structures on the cell surface. Therefore, nanoparticles, compared to larger (e.g., micrometer) particles, are considered to behave differently when they interact with cells. Nanoparticles in the Lung: Environmental Exposure and Drug Delivery provides a better understanding of how inhaled nanoparticles behave in the human lungs and body. Featuring contributions from renowned subject-matter experts, this authoritative text describes the sequence of events that nanoparticles encounter in the lungs when moving from the air into the bloodstream. This includes deposition, interactions with the alveolar surface and epithelium, translocation across the air-blood tissue barrier, and accumulation in the body. In addition, the book addresses practical considerations for drug delivery to the respiratory tract, drug and gene delivery in the lungs, and bio-nanocapsules. It considers the physicochemical, colloidal, and transport properties of nanoparticles, and presents cutting-edge research on special issues such as dosimetry for in vitro nanotoxicology, nanoparticle deposition in the developing lungs, and the potential for nose-to-brain delivery of drugs. Nanoparticles in the Lung: Environmental Exposure and Drug Delivery offers the most updated and comprehensive knowledge of the risks and benefits associated with nanoparticle inhalation--to protect humans from any harmful effects and to explore the utility of nanoparticles as drug delivery carriers.

Drug Delivery to the Lung

Drug Delivery to the Lung
Author: Hans Bisgaard
Publisher: CRC Press
Total Pages: 536
Release: 2001-10-02
Genre: Medical
ISBN: 0824741978

This book focuses on the aerosol treatment of lung diseases, recent improvements in the understanding of proper dosage, and major innovations in device technology applied to clinical practice. Examines the behavior of inspired spherical particles in the respiratory tract!Featuring over 1300 references, drawings, tables, and photographs.

Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems

Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems
Author: Kamal Dua
Publisher: Academic Press
Total Pages: 620
Release: 2020-08-04
Genre: Technology & Engineering
ISBN: 0128208880

Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems explores the development of novel therapeutics and diagnostics to improve pulmonary disease management, looking down to the nanoscale level for an efficient system of targeting and managing respiratory disease. The book examines numerous nanoparticle-based drug systems such as nanocrystals, dendrimers, polymeric micelles, protein-based, carbon nanotube, and liposomes that can offer advantages over traditional drug delivery systems. Starting with a brief introduction on different types of nanoparticles in respiratory disease conditions, the book then focuses on current trends in disease pathology that use different in vitro and in vivo models. The comprehensive resource is designed for those new to the field and to specialized scientists and researchers involved in pulmonary research and drug development. Explores recent perspectives and challenges regarding the management and diagnosis of chronic respiratory diseases Provides insights into how advanced drug delivery systems can be effectively formulated and delivered for the management of various pulmonary diseases Includes the most recent information on diagnostic methods and treatment strategies using controlled drug delivery systems (including nanotechnology)

Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer

Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer
Author: Prashant Kesharwani
Publisher: Academic Press
Total Pages: 340
Release: 2019-01-26
Genre: Business & Economics
ISBN: 0128163674

Nanotechnology-based Targeted Drug Delivery Systems for Lung Cancer is an indispensable resource that will help pharmaceutical scientists and clinical researchers design and develop novel drug delivery systems and devices for the treatment of lung cancer. As recent breakthroughs in nanomedicine are now making it possible to deliver drugs, genes and therapeutic agents to localized areas of disease to maximize clinical benefit, while also limiting unwanted side effects, this book explores promising approaches for the diagnosis and treatment of lung cancer using cutting-edge nanomedical technologies. Topics discussed include polymeric nanoparticles, solid lipid nanoparticles, liposomes, dendrimers, micelles and nanoemulsions. Provides an overview of an array of nanotechnology-based drug delivery systems Examines the design, synthesis and application of different nanocarriers in drug and gene delivery Provides an in-depth understanding of the design of targeted nanotherapeutics and technologies and its implication in various site-specific cancers

Handbook of Lung Targeted Drug Delivery Systems

Handbook of Lung Targeted Drug Delivery Systems
Author: Yashwant Pathak
Publisher: CRC Press
Total Pages: 1065
Release: 2021-10-18
Genre: Medical
ISBN: 1000450805

Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences covers every aspect of the drug delivery to lungs, the physiology and pharmacology of the lung, modelling for lung delivery, drug devices focused on lung treatment, regulatory requirements, and recent trends in clinical applications. With the advent of nano sciences and significant development in the nano particulate drug delivery systems there has been a renewed interest in the lung as an absorption surface for various drugs. The emergence of the COVID-19 virus has brought lung and lung delivery systems into focus, this book covers new developments and research used to address the prevention and treatment of respiratory diseases. Written by well-known scientists with years of experience in the field this timely handbook is an excellent reference book for the scientists and industry professionals. Key Features: Focuses particularly on the chemistry, clinical pharmacology, and biological developments in this field of research. Presents comprehensive information on emerging nanotechnology applications in diagnosing and treating pulmonary diseases Explores drug devices focused on lung treatment, regulatory requirements, and recent trends in clinical applications Examines specific formulations targeted to pulmonary systems

NanoBioMedicine

NanoBioMedicine
Author: Shailendra K. Saxena
Publisher: Springer Nature
Total Pages: 510
Release: 2020-02-03
Genre: Medical
ISBN: 9813298987

This book provides a comprehensive overview of the recent trends in various Nanotechnology-based therapeutics and challenges associated with its development. Nanobiotechnology is an interdisciplinary research that has wide applications in the various fields of biomedical research. The book discusses the various facets of the application of Nanotechnology in drug delivery, clinical diagnostics, Nanomedicine and treatment of infectious and chronic diseases. The book also highlights the recent advancements on important devices and applications that are based on Nanotechnology in medicine and brief the regulatory and ethical issues related to nanomedical devices. It also reviews the toxicological profile of various nanomaterials and emphasizes the need for safe nanomaterials for clinical use. Finally, the book discusses the recent developments of potential commercial applications of Nanotechnology.

Controlled Pulmonary Drug Delivery

Controlled Pulmonary Drug Delivery
Author: Hugh D.C. Smyth
Publisher: Springer Science & Business Media
Total Pages: 560
Release: 2011-06-24
Genre: Medical
ISBN: 1441997458

The pace of new research and level of innovation repeatedly introduced into the field of drug delivery to the lung is surprising given its state of maturity since the introduction of the pressurized metered dose inhaler over a half a century ago. It is clear that our understanding of pulmonary drug delivery has now evolved to the point that inhalation aerosols can be controlled both spatially and temporally to optimize their biological effects. These abilities include controlling lung deposition, by adopting formulation strategies or device technologies, and controlling drug uptake and release through sophisticated particle technologies. The large number of contributions to the scientific literature and variety of excellent texts published in recent years is evidence for the continued interest in pulmonary drug delivery research. This reference text endeavors to bring together the fundamental theory and practice of controlled drug delivery to the airways that is unavailable elsewhere. Collating and synthesizing the material in this rapidly evolving field presented a challenge and ultimately a sense of achievement that is hopefully reflected in the content of the volume.

Nanoparticles in Lung Cancer Therapy - Recent Trends

Nanoparticles in Lung Cancer Therapy - Recent Trends
Author: Abhijit Bandyopadhyay
Publisher: Springer
Total Pages: 78
Release: 2014-11-14
Genre: Science
ISBN: 8132221753

This brief provides an insight into the present scenario of the role of nanotechnology in the diagnosis and treatment of lung cancer at an early stage. Currently, lung cancer is the subject of major concern owing to the very high mortality rate throughout the world. Most of the conventional treatment methods such as surgery, chemotherapy, radiotherapy, etc., fail to prolong life of the patients. Incidents of recurrence are also very common in case of lung cancer. Researchers have shown that nanoparticles may act as a powerful anti cancer tool, especially for lung cancer. Unique surface properties and easy surface functionalization of nanoparticles enable early detection, diagnosis, imaging and treatment of lung cancer. The authors have elaborately presented how various nanoparticles (natural, semi synthetic and synthetic) may help in the treatment of lung cancer. They have also detailed works of various scientists who succeeded in developing effective nanoparticles and enabled very specific lung cancer therapy without any undesirable side effects and minimized death.

Pulmonary Nanomedicine

Pulmonary Nanomedicine
Author: Neeraj Vij
Publisher: CRC Press
Total Pages: 308
Release: 2012-08-06
Genre: Medical
ISBN: 9814364142

This book explores engineered nanomaterials (ENM) pulmonary effects and familiarizes readers with unique aspects of nanomaterial application and research. Focusing on the diagnostic and therapeutic utilities of nanomaterials in different lung diseases, it discusses the novel applications of nanotechnology for the treatment of airway diseases such a