Myeloproliferative Neoplasms An Issue Of Hematology Oncology Clinics Of North America Volume 35 2
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| Author | : John Mascarenhas |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 313 |
| Release | : 2021-02-27 |
| Genre | : Medical |
| ISBN | : 0323795897 |
This issue of Hematology/Oncology Clinics, guest edited by Drs. Ronald Hoffman, Ross Levine, John Mascarenhas, and Raajit Rampal, is dedicated to Myeloproliferative Neoplasms. This issue is one of six selected each year by the series consulting editors, Drs. George P. Canellos and Edward J. Benz. Topics in this issue include—but are not limited to— Overview of pathophysiology and potential drug targets, The role of the megakaryocyte, Epigenetics, Genetics, Novel technologies for understanding MPN biology, Important pathology considerations, Current Clinical investigations, Quality of life, Application of stem cell therapy, Immunotherapy approaches, Clinical unmet needs in ET/PV, Accelerated and blast phase MPNs, Epidemiology, Thrombotic and hemorrhagic complications, Murine modeling, The microenvironment in MPNs, MDS/MPN overlap syndrome, and Advancing effective clinical trial designs.
| Author | : John Mascarenhas |
| Publisher | : Elsevier |
| Total Pages | : 240 |
| Release | : 2021-04-28 |
| Genre | : Medical |
| ISBN | : 9780323795883 |
This issue of Hematology/Oncology Clinics, guest edited by Drs. Ronald Hoffman, Ross Levine, John Mascarenhas, and Raajit Rampal, is dedicated to Myeloproliferative Neoplasms. This issue is one of six selected each year by the series consulting editors, Drs. George P. Canellos and Edward J. Benz. Topics in this issue include-but are not limited to- Overview of pathophysiology and potential drug targets, The role of the megakaryocyte, Epigenetics, Genetics, Novel technologies for understanding MPN biology, Important pathology considerations, Current Clinical investigations, Quality of life, Application of stem cell therapy, Immunotherapy approaches, Clinical unmet needs in ET/PV, Accelerated and blast phase MPNs, Epidemiology, Thrombotic and hemorrhagic complications, Murine modeling, The microenvironment in MPNs, MDS/MPN overlap syndrome, and Advancing effective clinical trial designs.
| Author | : Fred J. Schiffman |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 256 |
| Release | : 2012-04-28 |
| Genre | : Medical |
| ISBN | : 1455744077 |
Topics include: Why does my patient have leukocytosis?, Why Is My Patient Neutropenic?, Does My Patient with a Serum Monoclonal Spike have Multiple Myeloma?, DVT and Pulmonary Embolism, Why Does My Patient Have Lymphadenopathy/Splenomegaly?,and Why Does My Patient have Thrombocytopenia?
| Author | : Bipin Savani |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 217 |
| Release | : 2016-03-25 |
| Genre | : Medical |
| ISBN | : 0323354599 |
This issue of Hematology/Oncology Clinics of North America, guest edited by Drs. Bipin Savani and Mohamad Mohty, is devoted to Bone Marrow Transplantation. Articles in this issue include: Acute Myeloid Leukemia (AML); Acute Lymphoid Leukemia (ALL); Myelodysplastic Syndrome (AML); Myeloproliferative disorders (MPD); Chronic Lymphoid Leukemia; Chronic Myeloid Leukemia (CML); Multiple Myeloma and Amyloidosis; Non-Hodgkin Lymphoma (NHL); Hodgkin Lymphoma (HL); Severe Aplastic Anemia (SAA) and Paroxysmal Nocturnal Hemoglobinuria (PNH); Sickle Cell Anemia; Thalassemia; Benign immunodeficiency diseases; and Referral to transplant centers.
| Author | : John C. Perkins |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : |
| Release | : 2017-11-06 |
| Genre | : Medical |
| ISBN | : 0323611486 |
This issue of Hematology/Oncology Clinics, edited by Drs. John Perkins and and Jonathan Davis, focuses on emergencies related to Hematology/Oncology and covers topics such as: Oncologic Mechanical Emergencies, Neutropenic Fever, Oncologic Metabolic Emergencies, Acute Leukemias, Pediatric Oncologic Emergencies, Chemotherapeutic Medications and their Emergent Complications, Anemia, Thrombotic Microangiopathies (TTP, HUS, HELLP), Congenital Bleeding Disorders, Acquired Bleeding Disorders and Antithrombotic agents, Sickle Cell Disease, and more!
| Author | : Tiziano Barbui |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 235 |
| Release | : 2012-02-03 |
| Genre | : Medical |
| ISBN | : 3642249884 |
This book focuses on three of the main categories of myeloproliferative neoplasm: polycythemia vera, essential thrombocythemia, and primary myelofibrosis. Relevant laboratory and clinical advances are comprehensively covered, and great emphasis is placed on the practical issues that challenge physicians in their daily practice. The main topics considered thus include contemporary diagnostic approaches, the value and limitations of mutation screening for diagnostic and prognostic purposes, risk stratification in terms of both survival and other disease complications such as leukemic transformation and thrombosis, and modern therapeutic strategies, including conventional drugs, allogeneic stem cell transplantation, and experimental drugs still under study. The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and up-to-date source of information from leading authorities in the field.
| Author | : Mohamed E. Salama |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 415 |
| Release | : 2020-09-01 |
| Genre | : Medical |
| ISBN | : 0323567347 |
Ideal as a quick, easy-to-use reference in the laboratory or clinical setting, Atlas of Diagnostic Hematology is an abundantly illustrated guide to the vast range of malignant and non-malignant disorders of the blood. More than 1,200 vibrant, full-color images enable you to identify and compare the unique clinical and histologic features of various blood disorders and confidently reach a diagnosis. Coverage includes photos of actual cases that span the entire range of this complex field, including rare conditions and difficult diagnoses. - Features more than 1,200 images including full-color pathologic and clinical images covering a wide range of hematologic malignant and non-malignant conditions. - Covers a range of disease stages, from the slightest indication where diagnosis can be complicated or missed entirely, to what the average blood or biopsy sample signifying disease may look like, to an advanced stage where disease indications are abundantly clear. - Helps you distinguish between similar and overlapping features and symptoms to arrive at an accurate diagnosis. - Provides up-to-date information on infectious processes in blood and bone marrow, classification system of myeloid neoplasms, and indolent and aggressive mature T and NK-cell lymphomas. - Includes diagnostic algorithms with differential diagnoses for conditions with similar histologic features and clinical symptoms. - Contains the latest WHO classifications for pathologic, genetic, and clinical information.
| Author | : Ronald L Hoffman, M D |
| Publisher | : ReadHowYouWant.com |
| Total Pages | : 570 |
| Release | : 2009-05-15 |
| Genre | : Health & Fitness |
| ISBN | : 1458701328 |
Now more than ever patients are taking control of their own health care, leaving many conventional physicians unsure about their role as dispensers of medical knowledge. More waiting rooms are now filled with highly informed medical consumers seeking to partner with their doctors. They want to explore all promising treatments, both mainstream and alternative, and connect emotionally. To physicians, these patients seem needy and demanding. They expect a lot of attention, but are all too quick to question authority and battle doctors for control of medical care. To patients, though, such physicians come off as distant and stodgy, even arrogant. Many walk away entirely from mainstream medicine seeking a better partnership or they neglect to mention the alternative treatments they're using for fear of disapproval. Less assertive patients simply clam up-put off by doctors' increasingly brusque bedside manner and shorthand use of ''medicalese.'' The unfortunate result in each case is the same: miscommunication and missed opportunities. Patients fail to receive the best care available to them, and doctor-patient relationships fall far short of the caring and mutually satisfying exchanges they should be.
| Author | : Vladimir A. Kuznetsov |
| Publisher | : Frontiers Media SA |
| Total Pages | : 121 |
| Release | : 2024-06-06 |
| Genre | : Medical |
| ISBN | : 2832550061 |
Cancer is a complex adaptive dynamic system that causes both local and systemic failures in the patient. Cancer is caused by a number of gain-of-function and loss-of-function events, that lead to cells proliferating without control by the host organism over time. In cancer, the immune system modulates cancer cell population heterogeneity and plays a crucial role in disease outcomes. The immune system itself also generates multiple clones of different cell types, with some clones proliferating quickly and maturing into effector cells. By creating regulatory signals and their networks, and generating effector cells and molecules, the immune system recognizes and kills abnormal cells. Anti-cancer immune mechanisms are realized as multi-layer, nonlinear cellular and molecular interactions. A number of factors determine the outcome of immune system-tumor interactions, including cancer-associated antigens, immune cells, and host organisms.
| Author | : Craig S. Kitchens |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 843 |
| Release | : 2013-02-20 |
| Genre | : Medical |
| ISBN | : 1455733296 |
A unique clinical focus makes Consultative Hemostasis and Thrombosis, 3rd Edition your go-to guide for quick, practical answers on managing the full range of bleeding and clotting disorders. Emphasizing real-world problems and solutions, Dr. Craig S. Kitchens, Dr. Barbara A. Konkle, and Dr. Craig M. Kessler provide all the clinical guidance you need to make optimal decisions on behalf of your patients and promote the best possible outcomes. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Efficiently look up concise descriptions of each condition, its associated symptoms, laboratory findings, diagnosis, differential diagnosis, and treatment. Get the latest information on hot topics such as Disseminated Intravascular Coagulation, Thrombophilia, Clinical and Laboratory Assessment and Management, Thrombotic -Thrombocytopenic Purpura, and Heparin-Induced Thrombocytopenia. Apply today’s newest therapies, including those that are quickly becoming standard in this fast-changing field. Meet the needs of specific patient groups with a new chapter on Bleeding and the Management of Hemorrhagic Disorders in Pregnancy and an extensively updated chapter on Thrombosis and Cancer. Zero in on key information with a new user-friendly design, and all-new full-color format, abundant laboratory protocols, and at-a-glance tables and charts throughout.
