Multiscale Modelling In Biomedical Engineering
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| Author | : Dimitrios I. Fotiadis |
| Publisher | : John Wiley & Sons |
| Total Pages | : 404 |
| Release | : 2023-05-05 |
| Genre | : Science |
| ISBN | : 1119517354 |
Multiscale Modelling in Biomedical Engineering Discover how multiscale modeling can enhance patient treatment and outcomes In Multiscale Modelling in Biomedical Engineering, an accomplished team of biomedical professionals delivers a robust treatment of the foundation and background of a general computational methodology for multi-scale modeling. The authors demonstrate how this methodology can be applied to various fields of biomedicine, with a particular focus on orthopedics and cardiovascular medicine. The book begins with a description of the relationship between multiscale modeling and systems biology before moving on to proceed systematically upwards in hierarchical levels from the molecular to the cellular, tissue, and organ level. It then examines multiscale modeling applications in specific functional areas, like mechanotransduction, musculoskeletal, and cardiovascular systems. Multiscale Modelling in Biomedical Engineering offers readers experiments and exercises to illustrate and implement the concepts contained within. Readers will also benefit from the inclusion of: A thorough introduction to systems biology and multi-scale modeling, including a survey of various multi-scale methods and approaches and analyses of their application in systems biology Comprehensive explorations of biomedical imaging and nanoscale modeling at the molecular, cell, tissue, and organ levels Practical discussions of the mechanotransduction perspective, including recent progress and likely future challenges In-depth examinations of risk prediction in patients using big data analytics and data mining Perfect for undergraduate and graduate students of bioengineering, biomechanics, biomedical engineering, and medicine, Multiscale Modelling in Biomedical Engineering will also earn a place in the libraries of industry professional and researchers seeking a one-stop reference to the basic engineering principles of biological systems.
| Author | : Vittorio Cristini |
| Publisher | : Cambridge University Press |
| Total Pages | : 299 |
| Release | : 2010-09-09 |
| Genre | : Technology & Engineering |
| ISBN | : 1139491504 |
Mathematical modeling, analysis and simulation are set to play crucial roles in explaining tumor behavior, and the uncontrolled growth of cancer cells over multiple time and spatial scales. This book, the first to integrate state-of-the-art numerical techniques with experimental data, provides an in-depth assessment of tumor cell modeling at multiple scales. The first part of the text presents a detailed biological background with an examination of single-phase and multi-phase continuum tumor modeling, discrete cell modeling, and hybrid continuum-discrete modeling. In the final two chapters, the authors guide the reader through problem-based illustrations and case studies of brain and breast cancer, to demonstrate the future potential of modeling in cancer research. This book has wide interdisciplinary appeal and is a valuable resource for mathematical biologists, biomedical engineers and clinical cancer research communities wishing to understand this emerging field.
| Author | : Thomas S. Deisboeck |
| Publisher | : CRC Press |
| Total Pages | : 492 |
| Release | : 2010-12-08 |
| Genre | : Mathematics |
| ISBN | : 1439814422 |
Cancer is a complex disease process that spans multiple scales in space and time. Driven by cutting-edge mathematical and computational techniques, in silico biology provides powerful tools to investigate the mechanistic relationships of genes, cells, and tissues. It enables the creation of experimentally testable hypotheses, the integration of dat
| Author | : Marco Scianna |
| Publisher | : CRC Press |
| Total Pages | : 300 |
| Release | : 2013-03-26 |
| Genre | : Mathematics |
| ISBN | : 1466514795 |
This work shows how the cellular Potts model can be used as a framework for model building and how extended models can achieve even better biological practicality, accuracy, and predictive power. It focuses on ways to integrate and interface the basic cellular Potts model at the mesoscopic scale with approaches that accurately model microscopic dynamics. These extensions are designed to create a nested and hybrid environment, where the evolution of a biological system is realistically driven by the constant interplay and flux of information between the different levels of description.
| Author | : Amit Gefen |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 397 |
| Release | : 2014-07-08 |
| Genre | : Technology & Engineering |
| ISBN | : 3642364829 |
This book reviews the state-of-the-art in multiscale computer modeling, in terms of both accomplishments and challenges. The information in the book is particularly useful for biomedical engineers, medical physicists and researchers in systems biology, mathematical biology, micro-biomechanics and biomaterials who are interested in how to bridge between traditional biomedical engineering work at the organ and tissue scales, and the newer arenas of cellular and molecular bioengineering.
| Author | : Nenad Filipovic |
| Publisher | : John Wiley & Sons |
| Total Pages | : 386 |
| Release | : 2021-12-14 |
| Genre | : Science |
| ISBN | : 1119563941 |
A systematic overview of the quickly developing field of bioengineering—with state-of-the-art modeling software! Computational Modeling and Simulation Examples in Bioengineering provides a comprehensive introduction to the emerging field of bioengineering. It provides the theoretical background necessary to simulating pathological conditions in the bones, muscles, cardiovascular tissue, and cancers, as well as lung and vertigo disease. The methodological approaches used for simulations include the finite element, dissipative particle dynamics, and lattice Boltzman. The text includes access to a state-of-the-art software package for simulating the theoretical problems. In this way, the book enhances the reader's learning capabilities in the field of biomedical engineering. The aim of this book is to provide concrete examples of applied modeling in biomedical engineering. Examples in a wide range of areas equip the reader with a foundation of knowledge regarding which problems can be modeled with which numerical methods. With more practical examples and more online software support than any competing text, this book organizes the field of computational bioengineering into an accessible and thorough introduction. Computational Modeling and Simulation Examples in Bioengineering: Includes a state-of-the-art software package enabling readers to engage in hands-on modeling of the examples in the book Provides a background on continuum and discrete modeling, along with equations and derivations for three key numerical methods Considers examples in the modeling of bones, skeletal muscles, cartilage, tissue engineering, blood flow, plaque, and more Explores stent deployment modeling as well as stent design and optimization techniques Generates different examples of fracture fixation with respect to the advantages in medical practice applications Computational Modeling and Simulation Examples in Bioengineering is an excellent textbook for students of bioengineering, as well as a support for basic and clinical research. Medical doctors and other clinical professionals will also benefit from this resource and guide to the latest modeling techniques.
| Author | : Guigen Zhang |
| Publisher | : CRC Press |
| Total Pages | : 480 |
| Release | : 2015-04-01 |
| Genre | : Medical |
| ISBN | : 1466517565 |
Arguably the first book of its kind, Computational Bioengineering explores the power of multidisciplinary computer modeling in bioengineering. Written by experts, the book examines the interplay of multiple governing principles underlying common biomedical devices and problems, bolstered by case studies. It shows you how to take advantage of the la
| Author | : |
| Publisher | : ScholarlyEditions |
| Total Pages | : 1153 |
| Release | : 2013-05-01 |
| Genre | : Technology & Engineering |
| ISBN | : 1490108718 |
Issues in Biomedical Engineering Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Reproductive Biomedicine. The editors have built Issues in Biomedical Engineering Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Reproductive Biomedicine in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biomedical Engineering Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
| Author | : Nenad Filipovic |
| Publisher | : Springer |
| Total Pages | : 169 |
| Release | : 2021-03-12 |
| Genre | : Technology & Engineering |
| ISBN | : 9783030436605 |
This book explores the latest and most relevant topics in the field of computational bioengineering and bioinformatics, with a particular focus on patient-specific, disease-progression modeling. It covers computational methods for cardiovascular disease prediction, with an emphasis on biomechanics, biomedical decision support systems, data mining, personalized diagnostics, bio-signal processing, protein structure prediction, biomedical image processing, analysis and visualization, and high-performance computing. It also discusses state-of-the-art tools for disease characterization, and recent advances in areas such as biomechanics, cardiovascular engineering, patient-specific modeling, population-based modeling, multiscale modeling, image processing, data mining, biomedical decision-support systems, signal processing, biomaterials and dental biomechanics, tissue and cell engineering, computational chemistry and high-performance computing. As such, it is a valuable resource for researchers, medical and bioengineering students, and medical device and software experts
| Author | : Milos Kojic |
| Publisher | : Academic Press |
| Total Pages | : 402 |
| Release | : 2022-09-11 |
| Genre | : Science |
| ISBN | : 0323906699 |
Computational Models in Biomedical Engineering: Finite Element Models Based on Smeared Physical Fields: Theory, Solutions, and Software discusses novel computational methodologies developed by the authors that address a variety of topics in biomedicine, with concepts that rely on the so-called smeared physical field built into the finite element method. A new and straightforward methodology is represented by their Kojic Transport Model (KTM), where a composite smeared finite element (CSFE) as a FE formulation contains different fields (e.g., drug concentration, electrical potential) in a composite medium, such as tissue, which includes the capillary and lymphatic system, different cell groups and organelles. The continuum domains participate in the overall model according to their volumetric fractions. The governing laws and material parameters are assigned to each of the domains. Furthermore, the continuum fields are coupled at each FE node by connectivity elements which take into account biological barriers such as vessel walls and cells. - Provides a methodology based on the smeared concept within the finite element method which is simple, straightforward and easy to use - Enables the modeling of complex physical field problems and the mechanics of biological systems - Includes features that are illustrated in chapters devoted to applications surrounding tissue, heart and lung - Includes a methodology that can serve as a basis for further enhancements by including additional phenomena which can be described by relevant relationships, derived theoretically or experimentally observed in laboratories and clinics
