Monitoring Forest Damage with Mass Spectrometry-Based Metabolomics Methods

Monitoring Forest Damage with Mass Spectrometry-Based Metabolomics Methods
Author: Carla Antonio
Publisher: John Wiley & Sons
Total Pages: 468
Release: 2023-11-02
Genre: Science
ISBN: 1119868742

Monitoring Forest Damage with Mass Spectrometry-Based Metabolomics Methods Understand forest responses to climate change with this timely introduction Forests are among the most critical parts of our global ecosystem, responsible for the air we breathe, home to most of the earth’s species, and crucial sources of food and raw materials. Forest development is therefore one of the most important areas of ecological study, and damage to forests is potentially existential. Metabolomics, a toolkit which accrues data on interactions between genetic and environmental conditions, promises to advance our understanding of how these vital ecosystems respond to dramatic changes in climate and environment. Monitoring Forest Damage with Mass Spectrometry-Based Metabolomics Methods offers a thorough, accessible discussion of metabolomic techniques and their applications in forest tree research. It promises to enrich the reader’s understanding of how forests are being transformed by globe-spanning changes, and to arm researchers with tools for reacting to these potentially epochal developments. Monitoring Forest Damage with Mass Spectrometry-Based Metabolomics Methods readers will also find: Analysis of specialized secondary metabolites such as phytohormones Detailed discussion of ecologically important tree genera such as Pinus, Populus, Quercus, and many more Supplementary materials related to study design, sample preparation, and instrumental analysis protocols Monitoring Forest Damage with Mass Spectrometry-Based Metabolomics Methods is ideal for researchers in analytical chemistry, mass spectrometry, metabolomics, forest research, the life sciences, and all other related fields.

Environmental Metabolomics

Environmental Metabolomics
Author: Diana Alvarez-Munoz
Publisher: Elsevier
Total Pages: 368
Release: 2020-05-20
Genre: Science
ISBN: 0128181966

Environmental Metabolomics Applications in Field and Laboratory Studies: From the Exposome to the Metabolome presents an overview of the current state of aquatic environments and problems caused by human pressure and daily life. The presence of contaminants in nature and their effects are evaluated, along with recommendations for preservation. This book not only shows readers how to implement techniques, it also guides them through the process. As metabolomics becomes a more routine technique for environmental studies and future perspectives, a guide for validation and globalization of current approaches is needed.

The Handbook of Metabonomics and Metabolomics

The Handbook of Metabonomics and Metabolomics
Author: John C. Lindon
Publisher: Elsevier
Total Pages: 573
Release: 2011-08-11
Genre: Science
ISBN: 0080468004

Molecular biology operates at three levels – genes, proteins and metabolites. This book is unique in that it provides a comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies (genomics and proteomics). These "omics" methods form the basis for understanding biology at a systems level. The Handbook of Metabonomics and Metabolomics aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification, encompassing the fields of metabonomics and metabolomics. It covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications.* comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies* aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification* covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications.

Methodologies for Metabolomics

Methodologies for Metabolomics
Author: Norbert W. Lutz
Publisher: Cambridge University Press
Total Pages: 641
Release: 2013-01-21
Genre: Medical
ISBN: 0521765900

Metabolomics, the global characterisation of the small molecule complement involved in metabolism, has evolved into a powerful suite of approaches for understanding the global physiological and pathological processes occurring in biological organisms. The diversity of metabolites, the wide range of metabolic pathways and their divergent biological contexts require a range of methodological strategies and techniques. Methodologies for Metabolomics provides a comprehensive description of the newest methodological approaches in metabolomic research. The most important technologies used to identify and quantify metabolites, including nuclear magnetic resonance and mass spectrometry, are highlighted. The integration of these techniques with classical biological methods is also addressed. Furthermore, the book presents statistical and chemometric methods for evaluation of the resultant data. The broad spectrum of topics includes a vast variety of organisms, samples and diseases, ranging from in vivo metabolomics in humans and animals to in vitro analysis of tissue samples, cultured cells and biofluids.

Advances in Gas Chromatography

Advances in Gas Chromatography
Author: Xinghua Guo
Publisher: BoD – Books on Demand
Total Pages: 226
Release: 2014-02-26
Genre: Science
ISBN: 9535112279

For decades gas chromatography has been and will remain an irreplaceable analytical technique in many research areas for both quantitative analysis and qualitative characterization/identification, which is still supplementary with HPLC. This book highlights a few areas where significant advances have been reported recently and/or a revisit of basic concepts is deserved. It provides an overview of instrumental developments, frontline and modern research as well as practical industrial applications. The topics include GC-based metabolomics in biomedical, plant and microbial research, natural products as well as characterization of aging of synthetic materials and industrial monitoring, which are contributions of several experts from different disciplines. It also contains best hand-on practices of sample preparation (derivatization) and data processing in daily research. This book is recommended to both basic and experienced researchers in gas chromatography.

NMR-Based Metabolomics

NMR-Based Metabolomics
Author: G. A. Nagana Gowda
Publisher: Humana
Total Pages: 489
Release: 2020-08-29
Genre: Science
ISBN: 9781493996926

This book provides broad coverage of nuclear magnetic resonance (NMR) spectroscopy-based methods and applications for the analysis of metabolites in a wide range of biological samples, from biofluids, cells, animal models, human, to plants and foods. The applications range from mechanistic understanding, biomarker discovery, environmental studies, and drug discovery to nutrition, while NMR methods include global, targeted, and isotope tracer-based techniques. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, NMR-Based Metabolomics: Methods and Protocols serves as a wealth of information for beginners as well as advanced practitioners and also as stepping stones for further advances in the field of metabolomics.

Metabolomics for Biomedical Research

Metabolomics for Biomedical Research
Author: Jerzy Adamski
Publisher: Academic Press
Total Pages: 266
Release: 2020-03-21
Genre: Medical
ISBN: 0128127848

Metabolomics for Biomedical Research brings together recent progress on study design, analytics, biostatistics and bioinformatics for the success of metabolomics research. Metabolomics represents a very interdisciplinary research prominent in the functional analyses of living systems; hence, this book focuses on translation and medical aspects. The book discusses topics such as biomarkers and their requirements to be used in medical research, with the parameters and approaches on how to validate their quality; and animal models and other approaches, as stem cells and organoid culture. Additionally, it explains how metabolomics may be applied in prediction of individual response to drug or disease progression. This book is a valuable source for researchers on systems biology and other members of biomedical field interested in metabolism-oriented studies for medical research.

Metabolomics Tools for Natural Product Discovery

Metabolomics Tools for Natural Product Discovery
Author: Ute Roessner
Publisher: Humana
Total Pages: 0
Release: 2016-08-23
Genre: Medical
ISBN: 9781493963010

Classical natural product chemistry is transitioning to modern day metabolomics as a result of the advent of comprehensive analytical platforms and sensitive analytical instrumentation. Therefore, it is worthwhile to summarize recent developments with current analytical platforms and highlight how metabolomics is being integrated into this classical field to dereplicate and profile natural product extracts. Metabolomics Tools for Natural Product Discoveries: Methods and Protocols aims to unite diverse and recently developed methodologies and protocols in order to identify bioactive secondary metabolites for the purpose of drug discovery. Some topics covered in this volume include applications for the extraction of selected natural products from less common sources such as bryophytes and hard corals, various biological assays, comprehensive applications and strategies for GC-MS, LC-MS, and NMR, as well as protocols and strategies for the structure elucidation of isolated natural products. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible Metabolomics Tools for Natural Product Discoveries: Methods and Protocols seeks to serve both professionals and research students with its well-honed methodologies for natural product isolation, biomarker discovery, dereplication, biological assays, and comprehensive metabolomic platforms available for high-throughput analyses.

Viral Pathogenesis

Viral Pathogenesis
Author: Michael G. Katze
Publisher: Academic Press
Total Pages: 368
Release: 2015-12-30
Genre: Medical
ISBN: 0128011742

Viral Pathogenesis: From Basics to Systems Biology, Third Edition, has been thoroughly updated to cover topical advances in the evolving field of viral pathogenesis, while also providing the requisite classic foundational information for which it is recognized. The book provides key coverage of the newfound ability to profile molecular events on a system-wide scale, which has led to a deeper understanding of virus-host interactions, host signaling and molecular-interaction networks, and the role of host genetics in determining disease outcome. In addition, the content has been augmented with short chapters on seminal breakthroughs and profiles of their progenitors, as well as short commentaries on important or controversial issues in the field. Thus, the reader will be given a view of virology research with perspectives on issues such as biomedical ethics, public health policy, and human health. In summary, the third edition will give the student a sense of the exciting new perspectives on viral pathogenesis that have been provided by recent developments in genomics, computation, modeling, and systems biology. - Covers all aspects of viral infection, including viral entry, replication, and release, as well as innate and adaptive immunity and viral pathogenesis - Provides a fresh perspective on the approaches used to understand how viruses cause disease - Features molecular profiling techniques, whole genome sequencing, and innovative computational methods - Highlights the use of contemporary approaches and the insights they provide to the field

Environmental Physiology of Plants

Environmental Physiology of Plants
Author: Alastair Fitter
Publisher:
Total Pages: 423
Release: 1987
Genre: Science
ISBN: 9780122577642

Plant growth; The influence of the environment; Population responses; Adaptability and adaptedness; The acquisition of resources; Energy and carbon; Mineral nutrients; Water; Responses to environmental stress; Temperature; Ionic toxicity; Gaseous toxicity; Interactions between organisms; An ecological perspective.