Molecularly Imprinted Polymers as Advanced Drug Delivery Systems

Molecularly Imprinted Polymers as Advanced Drug Delivery Systems
Author: Zhaosheng Liu
Publisher: Springer Nature
Total Pages: 218
Release: 2021-04-23
Genre: Medical
ISBN: 9811602271

This book summarizes the recent advancements for drug delivery systems (DDS) in terms of fundamental principles, rapidly emerging techniques and developing frontiers of molecular imprinting. Especially with the combination of enantioselective molecularly imprinted polymers and water compatible molecularly imprinted polymers, stimuli responsive imprinted DDS have been innovated and applied to dermal delivery, ophthalmic drugs and cancer treatment. This philosophy comprehensively revolutionizes the treatment strategy of human healthcare and provides the possibility to re-trigger in vivo an exhaust system after the complete release of the starting drug cargo, thus enabling precision medicine. To this end, the following unique features will be discussed and concluded: 1) State-of-the-art definition of MIP as drug delivery systems. 2) Advanced techniques and clinical applications of MIP as drug delivery systems in the past decade. 3) Novel frontiers and brand-new technologies, for example, drug delivery devices for zero-order sustained release and stimuli responsive imprinted DDS. 4) Revolutionary impact on dermal delivery, ophthalmic drugs and cancer treatment. 5) Future challenges and perspectives

Molecularly Imprinted Polymer Composites

Molecularly Imprinted Polymer Composites
Author: Sooraj M.P.
Publisher: Woodhead Publishing
Total Pages: 442
Release: 2020-12-01
Genre: Technology & Engineering
ISBN: 0128203854

Molecular Imprinted Polymer Composites: Synthesis, Characterisation and Applications covers the design of composite materials containing nanostructures and molecular imprinted polymers that has materialized the ever-sought out vision of homogeneous molecular imprinted polymers. The inherent high surface-to-volume ratio of nanostructures has served well in increasing the surface area of conventional bulk polymers. In recent decades, molecularly imprinted polymer nanocomposite materials have attracted much attention for their potential applications in the fields of separation science, sensing, drug delivery, waste water treatment and catalysis, hence this book provides a much needed update on progress. - Includes information on molecular imprinted polymer composites and their potential for commercialization - Discusses their synthesis, characterization and applications - Analyzes the effect of incorporation of different nanostructures on the thermodynamic, kinetic and adsorption behavior of imprinted sorbents

Drug Delivery Systems in Cancer Therapy

Drug Delivery Systems in Cancer Therapy
Author: Dennis M. Brown
Publisher: Humana Press
Total Pages: 0
Release: 2010-11-19
Genre: Medical
ISBN: 9781617372384

Leading experts survey the currently available technologies designed to improve the delivery of today's cancer chemotherapeutic agents. The authors review both the theoretical and practical considerations governing conventional and nonconventional methods of drug administration, and identify promising opportunities for product development. In their outline and discussion of the use of novel formulation technologies-including synthetic polymers and biomaterials for prolonged or sustained drug release to achieve potentially greater therapeutic effect-they profile those technologies that have resulted in a number of approved and late-stage clinical products.

Smart Polymeric Nano-Constructs in Drug Delivery

Smart Polymeric Nano-Constructs in Drug Delivery
Author: Suresh P Vyas
Publisher: Academic Press
Total Pages: 626
Release: 2022-11-12
Genre: Medical
ISBN: 0323913997

Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications provides a thorough discussion of the most state of the art material and polymer exploitations for the delivery of bioactive(s) as well as their current and clinical status. The book enables researchers to prepare a variety of smart drug delivery systems to investigate their properties as well as to discover their uses and applications. The novelty of this approach addresses an existing need of exhaustively understanding the potential of the materials including polymeric drug delivery systems that are smartly designed to deliver bioactive(s) into the body at targeted sites without showing side effects. The book is helpful for those in the health sector, specifically those developing nanomedicine using smart material-based nano-delivery systems. Polymers have unique co-operative properties that are not found with low-molecular-weight compounds along with their appealing physical and chemical properties, constituting the root of their success in drug delivery. Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications discusses smart and stimuli responsive polymers applicable in drug delivery, followed detailed information about various concepts and designing of polymeric novel drug delivery systems for treatment of various type of diseases, also discussing patents related to the field. The book helps readers to design and develop novel drug delivery systems based on smart materials for the effective delivery of bioactive that take advantage of recent advances in smart polymer-based strategies. It is useful to those in pharmaceutical sciences and related fields in developing new drug delivery systems. - Provides comprehensive overview of the potential role of polymeric systems in drug delivery - Explores the design, synthesis, and application of different smart material-based delivery systems - Includes fundamental and clinical applications

Ligand

Ligand
Author: Chandraleka Saravanan
Publisher: BoD – Books on Demand
Total Pages: 122
Release: 2018-05-23
Genre: Science
ISBN: 1789231825

The book Ligand describes the diversity and versatility of ligands, covering structural features, donor-acceptor properties and secondary functions like molecular recognition. Moreover, this book also provides a comprehensive account on the applicability like catalysis, sensors, supramolecular assembly, photochemical property, bioinorganic chemistry, and so on. The advancement of fundamentals in ligand design and the control of physicochemical properties of coordination compounds has largely increased emphasis on understanding the structural and electronic features toward different perspectives in materials science. In this regard, this book has a special appeal to chemists, biologists and others. This book will be beneficial for the graduate students, teachers, researchers and other professionals who are interested to fortify and expand their knowledge in chemistry, biology, microbiology, biotechnology, materials science, environmental science and so on.

Advanced Molecularly Imprinting Materials

Advanced Molecularly Imprinting Materials
Author: Ashutosh Tiwari
Publisher: John Wiley & Sons
Total Pages: 621
Release: 2016-11-02
Genre: Science
ISBN: 1119336163

Molecularly imprinted polymers (MIPs) are an important functional material because of their potential implications in diverse research fields. The materials have been developed for a range of uses including separation, environmental, biomedical and sensor applications. In this book, the chapters are clustered into two main sections: Strategies to be employed when using the affinity materials, and rational design of MIPs for advanced applications. In the first part, the book covers the recent advances in producing MIPs for sample design, preparation and characterizations. In the second part, the chapters demonstrate the importance and novelty of creation of recognition imprinted on the materials and surfaces for a range of microbial detection sensors in the biomedical, environmental and food safety fields as well as sensing human odor and virus monitoring systems. Part 1: Strategies of affinity materials Molecularly imprinted polymers MIP nanomaterials Micro- and nanotraps for solid phase extraction Carbonaceous affinity nanomaterials Fluorescent MIPs MIP-based fiber optic sensors Part 2: Rational design of MIP for advanced applications MIP-based biomedical and environmental sensors Affinity adsorbents for environmental biotechnology MIP in food safety MIP-based virus monitoring MIP-based drug delivery and controlled release Biorecognition imprints on the biosensor surfaces MIP-based sensing of volatile organic compounds in human body odour MIP-based microcantilever sensor system

Biopolymers

Biopolymers
Author: Magdy Elnashar
Publisher: BoD – Books on Demand
Total Pages: 634
Release: 2010-09-28
Genre: Technology & Engineering
ISBN: 9533071095

Biopolymers are polymers produced by living organisms. Cellulose, starch, chitin, proteins, peptides, DNA and RNA are all examples of biopolymers. This book comprehensively reviews and compiles information on biopolymers in 30 chapters. The book covers occurrence, synthesis, isolation and production, properties and applications, modification, and the relevant analysis methods to reveal the structures and properties of some biopolymers. This book will hopefully be of help to many scientists, physicians, pharmacists, engineers and other experts in a variety of disciplines, both academic and industrial. It may not only support research and development, but be suitable for teaching as well.

Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment

Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment
Author: Jorge Coelho
Publisher: Springer Science & Business Media
Total Pages: 433
Release: 2013-03-15
Genre: Medical
ISBN: 9400760108

This book is part of a series dedicated to recent advances on preventive, predictive and personalised medicine (PPPM). It focuses on the theme of “Drug delivery systems: advanced technologies potentially applicable in personalised treatments”. The critical topics involving the development and preparation of effective drug delivery systems, such as: polymers available, self-assembly, nanotechnology, pharmaceutical formulations, three dimensional structures, molecular modeling, tailor-made solutions and technological tendencies, are carefully discussed. The understanding of these areas constitutes a paramount route to establish personalised and effective solutions for specific diseases and individuals.

Handbook of Molecular Imprinting

Handbook of Molecular Imprinting
Author: Seung-Woo Lee
Publisher: CRC Press
Total Pages: 636
Release: 2012-09-18
Genre: Technology & Engineering
ISBN: 9814316652

Molecular imprinting focuses on the fabrication of an artificial receptor with perfect molecular recognition abilities. It has attracted a great deal of scientific attention because of the enormous opportunities it opens in the fields of separation, catalysis, and analysis. The advantages of the molecular imprinting enable to target a wide class of substances ranging from small molecules to big conglomerates, such as proteins or even cells. In recent years, sensor applications based on molecular imprinting have started to attract greater attention because of the easy creation of robust receptor sites with high specificity and sensitivity toward a target compound. A collection of contributions from distinguised experts, Handbook of Molecular Imprinting: Advanced Sensor Applications provides a comprehensive overview on the specific challenges of molecular imprinting in sensor applications. It covers various molecular imprinting approaches. As a result, a perspective of future device ensembles for sensing is acquired. The text lays particular emphasis on fundamental aspects as well as novel ideas in the context of sensor applications. It also highlights the operation principles of various sensor transducers that are generally employed in combination with molecular imprinting recognition elements.