Molecular Mechanisms Of Parasite Invasion
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| Author | : Barbara A. Burleigh |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 255 |
| Release | : 2008-12-05 |
| Genre | : Medical |
| ISBN | : 0387782672 |
All of the parasitic organisms highlighted in this new book represent medically important human pathogens that contribute significantly to the global burden of disease. As such there is intense interest in understanding the molecular basis of infection by these pathogens—not only with regard to their clinical relevance but also the fascinating biology they reveal. For most of the parasites discussed here the ability to penetrate biological barriers and/or to establish intracellular residence is critical to survival of the pathogen in the mammalian hosts. For other parasites, a tissue invasive phenotype is a key virulence determinant. In the ensuing 18 chapters, select members of this diverse set of protozoan parasites, as well as some examples of the extremely reduced fungal parasites classified as Microsporidia, are discussed within the context of the fascinating molecular strategies employed by these organisms to migrate across biological barriers and to establish residence within target host cells.
| Author | : Joseph Marr |
| Publisher | : Elsevier |
| Total Pages | : 363 |
| Release | : 1995-09-06 |
| Genre | : Science |
| ISBN | : 0080527884 |
The study of parasitic organisms at the molecular level has yielded fascinating new insights of great medical, social, and economical importance, and has pointed the way for the treatment and prevention of the diseases they cause. Biochemistry and Molecular Biology of Parasites presents an up-to-date account of this modern scientific discipline in a manner that allows and encourages the reader to place the biochemistry and molecular biology of these organisms in their biological context. The chapters are cross-referenced and grouped in an arrangement that provides a fully integrated whole, and permits the reader to create a composite of the biochemical function of these organisms.Individual chapter includes those devoted to metabolism, in both aerobic and anaerobic protozoa; antioxidant mechanisms; parasite surfaces; organelles; invasion mechanisms; and chemotherapy. The helminths are discussed not only from the point of view of their cellular biochemistry and metabolism, but also with respect to both their integrated functions such as neurochemistry, structure and functions of surfaces, and reproduction. Written by expert investigators, this book will be of interest to all experienced researchers, graduate students, and to the newcomer eager to become familiar with the biochemistry and molecular biology of parasites.
| Author | : |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2002 |
| Genre | : Cells |
| ISBN | : 9780815332183 |
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 312 |
| Release | : 1991-02-01 |
| Genre | : Medical |
| ISBN | : 9780309045278 |
Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities. The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the: Nature, clinical manifestations, diagnosis, and epidemiology of malaria. Biology of the malaria parasite and its vector. Prospects for developing malaria vaccines and improved treatments. Economic, social, and behavioral factors in malaria control.
| Author | : Steven A. Frank |
| Publisher | : Princeton University Press |
| Total Pages | : 364 |
| Release | : 2002-07-21 |
| Genre | : Medical |
| ISBN | : 9780691095950 |
| Author | : Barbara A. Burleigh |
| Publisher | : |
| Total Pages | : 237 |
| Release | : 2010 |
| Genre | : Actins / physiology |
| ISBN | : |
| Author | : Richard Dawkins |
| Publisher | : OUP Oxford |
| Total Pages | : 240 |
| Release | : 2012-06-07 |
| Genre | : Science |
| ISBN | : 0191631655 |
Parasites that manipulate the behaviour of their hosts represent striking examples of adaptation by natural selection. This field of study is now moving beyond its descriptive phase and into more exciting areas where the processes and patterns of such dramatic adaptations can be better understood. This innovative text provides an up-to-date, authoritative, and challenging review of host manipulation by parasites that assesses the current state of developments in the field and lays out a framework for future research. It also promotes a greater integration of behavioral ecology with studies of host manipulation (behavioral ecology has tended to concentrate mainly on behaviour expressed by free living organisms and is far less focused on the role of parasites in shaping behaviour). To help achieve this, the editors adopt a novel approach of having a prominent expert on behavioral ecology (but who does not work directly on parasites) to provide an afterword to each chapter.
| Author | : Louis M. Weiss |
| Publisher | : Academic Press |
| Total Pages | : 1109 |
| Release | : 2013-08-10 |
| Genre | : Science |
| ISBN | : 0123965365 |
This 2e of Toxoplasma gondii reflects the significant advances in the field in the last 5 years, including new information on the genomics, epigenomics and proteomics of T. gondii as well as a new understanding of the population biology and genetic diversity of this organism. T. gondii remains the best model system for studying the entire Apicomplexa group of protozoans, which includes Malaria, making this new edition essential for a broad group of researchers and scientists. Toxoplasmosis is caused by a one-celled protozoan parasite known as T. gondii. The infection produces a wide range of clinical syndromes in humans, land and sea mammals, and various bird species. Most humans contract toxoplasmosis by eating contaminated, raw or undercooked meat (particularly pork), vegetables, or milk products; by coming into contact with the T. gondii eggs from cat feces; or by drinking contaminated water. The parasite damages the ocular and central nervous systems, causing behavioral and personality alterations as well as fatal necrotizing encephalitis. It is especially dangerous for the fetus of an infected pregnant woman and for individuals with compromised immune systems, such as HIV-infected patients. - Completely updated, the 2e presents recent advances driven by new information on the genetics and genomics of the pathogen - Provides the latest information concerning the epidemiology, diagnosis, treatment and prevention of toxoplasmosis - Offers a single-source reference for a wide range of scientists and physicians working with this pathogen, including parasitologists, cell and molecular biologists, veterinarians, neuroscientists, physicians, and food scientists
| Author | : John M. Kelly |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 180 |
| Release | : 2003-08-31 |
| Genre | : Medical |
| ISBN | : 9780306478499 |
Chagas' disease, which results from infection with the single cell parasite Trypanosoma cruzi, is a debilitating condition that is a major problem in many parts of Latin America. Rapid technical progress is now facilitating dissection of the molecular mechanisms of disease pathogenesis, a process that will ultimately provide new strategies to alleviate the enormous public health burden associated with the infection. In this book, international experts review the buoyant status of Chagas' disease research as we enter the "post-genome" era and speculate on how the new findings will impact on drug and vaccine development. The chapters outline how progress is being made on several fronts ranging from parasite population genetics to human immunology. Researchers, physicians and students with an interest in any aspect of molecular parasitology should find this book to be a valuable reference
| Author | : Merlin Willcox |
| Publisher | : CRC Press |
| Total Pages | : 464 |
| Release | : 2004-06-28 |
| Genre | : Health & Fitness |
| ISBN | : 0203502329 |
Malaria is an increasing worldwide threat, with more than three hundred million infections and one million deaths every year. The worlds poorest are the worst affected, and many treat themselves with traditional herbal medicines. These are often more available and affordable, and sometimes are perceived as more effective than conventional antimala
