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| Author | : Luca Saba |
| Publisher | : Oxford University Press, USA |
| Total Pages | : 585 |
| Release | : 2015 |
| Genre | : Medical |
| ISBN | : 0199671613 |
This text summarizes the latest developments in imaging techniques and other new diagnostic methods as applied to the neurodegenerative disorders.
| Author | : Rudi A.J.O. Dierckx |
| Publisher | : Springer |
| Total Pages | : 1103 |
| Release | : 2014-06-02 |
| Genre | : Medical |
| ISBN | : 3642543073 |
PET and SPECT in Neurology highlight the combined expertise of renowned authors whose dedication to the investigation of neurological disorders through nuclear medicine technology has achieved international recognition. Classical neurodegenerative disorders are discussed as well as cerebrovascular disorders, brain tumors, epilepsy, head trauma, coma, sleeping disorders and inflammatory and infectious diseases of the CNS. The latest results in nuclear brain imaging are detailed. Most chapters are written jointly by a clinical neurologist and a nuclear medicine specialist to ensure a multidisciplinary approach. This state-of-the-art compendium will be valuable not only to neurologists and radiologists/nuclear medicine specialists but also to interested general practitioners and geriatricians. It is the second volume of a trilogy on PET and SPECT imaging in the neurosciences, the other volumes covering PET and SPECT in psychiatry and in neurobiological systems.
| Author | : Frederik Barkhof |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 295 |
| Release | : 2011-02-11 |
| Genre | : Medical |
| ISBN | : 3642008186 |
This up-to-date, superbly illustrated book is a practical guide to the effective use of neuroimaging in the patient with cognitive decline. It sets out the key clinical and imaging features of the various causes of dementia and directs the reader from clinical presentation to neuroimaging and on to an accurate diagnosis whenever possible. After an introductory chapter on the clinical background, the available "toolbox" of structural and functional neuroimaging techniques is reviewed in detail, including CT, MRI and advanced MR techniques, SPECT and PET, and image analysis methods. The imaging findings in normal ageing are then discussed, followed by a series of chapters that carefully present and analyze the key findings in patients with dementias. Throughout, a practical approach is adopted, geared specifically to the needs of clinicians (neurologists, radiologists, psychiatrists, geriatricians) working in the field of dementia, for whom this book will prove an invaluable resource.
| Author | : Patricia A. Broderick |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 313 |
| Release | : 2007-11-05 |
| Genre | : Medical |
| ISBN | : 1592598889 |
Bioimaging is in the forefront of medicine for the diagnosis and helps to predict the progression of AD via mild cognitive treatment of neurodegenerative disease. Conventional magnetic impairment (MCI) studies. resonance imaging (MRI) uses interactive external magnetic fields Novel neuroimaging technologies, such as neuromolecular and resonant frequencies of protons from water molecules. imaging (NMI) with a series of newly developed BRODERICK ® However, newer sequences, such as magnetization-prepared rapid PROBE sensors, directly image neurotransmitters, precursors, acquisition gradient echo (MPRAGE), are able to seek higher and metabolites in vivo, in real time and within seconds, at separate levels of anatomic resolution by allowing more rapid temporal and selective waveform potentials. NMI, which uses an imaging. Magnetic resonance spectroscopy (MRS) images electrochemical basis for detection, enables the differentiation of metabolic changes, enabling underlying pathophysiologic neurodegenerative diseases in patients who present with mesial dysfunction in neurodegeneration to be deciphered. Neuro- versus neocortical temporal lobe epilepsy. In fact, NMI has some 1 chemicals visible with proton H MRS include N-acetyl aspartate remarkable similarities to MRI insofar as there is technological (NAA), creatine/phosphocreatine (Cr), and choline (Cho); NAA dependence on electron and proton transfer, respectively, and is considered to act as an in vivo marker for neuronal loss and/or further dependence is seen in both NMI and MRI on tissue neuronal dysfunction. By extending imaging to the study of composition such as lipids.
| Author | : Philip Seeman |
| Publisher | : Elsevier |
| Total Pages | : 534 |
| Release | : 2013-11-15 |
| Genre | : Science |
| ISBN | : 012418684X |
Brain imaging technology remains at the forefront of advances in both our understanding of the brain and our ability to diagnose and treat brain disease and disorders. Imaging of the Human Brain in Health and Disease examines the localization of neurotransmitter receptors in the nervous system of normal, healthy humans and compares that with humans who are suffering from various neurologic diseases. Opening chapters introduce the basic science of imaging neurotransmitters, including sigma, acetylcholine, opioid, and dopamine receptors. Imaging the healthy and diseased brain includes brain imaging of anger, pain, autism, the release of dopamine, the impact of cannabinoids, and Alzheimer's disease. This book is a valuable companion to a wide range of scholars, students, and researchers in neuroscience, clinical neurology, and psychiatry, and provides a detailed introduction to the application of advanced imaging to the treatment of brain disorders and disease. - A focused introduction to imaging healthy and diseased brains - Focuses on the primary neurotransmitter release - Includes sigma, acetylcholine, opioid, and dopamine receptors - Presents the imaging of healthy and diseased brains via anger, pain, autism, and Alzheimer's disease
| Author | : M. Flint Beal |
| Publisher | : Cambridge University Press |
| Total Pages | : 1009 |
| Release | : 2005-06-02 |
| Genre | : Medical |
| ISBN | : 1139443453 |
Neurodegenerative diseases are major contributors to disability and disease, with Alzheimer's and Parkinson's diseases the most prevalent. This major reference reviews the rapidly advancing knowledge of pathogenesis and treatment of neurodegenerative diseases in the context of a comprehensive survey of each disease and its clinical features. The editors and contributors are among the leading experts in the field internationally. Covering basic science, diagnostic tools and therapeutic approaches, the book focuses on all aspects of neurodegenerative disease, including the normal aging process. The dementias, prion diseases, Parkinson's disease and atypical parkinsonisms, neurodegenerative ataxias, motor neuron diseases, degenerative diseases with chorea, iron and copper disorders, and mitochondrial diseases, are all methodically presented and discussed, with extensive illustrations. In each case the underlying genetics, neuropathological and clinical issues are fully reviewed, making this the most complete as well as the most authoritative reference available to clinicians and neuroscientists.
| Author | : Donna J. Cross |
| Publisher | : Springer Nature |
| Total Pages | : 340 |
| Release | : 2023-09-26 |
| Genre | : Medical |
| ISBN | : 3031350987 |
This book provides a comprehensive review of the role of molecular imaging in neurodegenerative diseases. A growing field, molecular imaging of neurodegeneration is becoming increasingly relevant with an aging population, and this book serves to provide both an introduction to the concept and background of neurodegeneration and an update on the most recent imaging advances. Throughout, chapters will review current applications of neuroimaging in neurodegenerative disorders, like dementia and movement disorders, and increase knowledge of quantification and semi-quantification methods for neuroimaging. Imaging methods such as PET/CT and PET/MR are covered, as well as more advanced technologies like artificial intelligence algorithms and novel radiotracers. Chapters are also intended to improve competency in reporting and interpretation skills with structured information on current practice. The book concludes with a collection of up to date practice cases for the interpretation of neurodegeneration in nuclear medicine imaging. This is an ideal guide for nuclear medicine physicians, neuroradiologists, neurologists, residents, trainees, and related medical professionals caring for patients with neurodegeneration.
| Author | : Andrea Varrone |
| Publisher | : Springer Nature |
| Total Pages | : 180 |
| Release | : 2021-11-10 |
| Genre | : Medical |
| ISBN | : 3030835987 |
This book gathers a collection of cases with challenging diagnoses, in which nuclear medicine examinations have been particularly helpful in terms of the final diagnosis or follow-up. The cases presented chiefly involve patients with neurodegenerative disorders, epilepsy and brain tumors. The book is intended for nuclear medicine specialists as well as clinicians, offering essential guidance on the interpretation of neurology cases in the clinical setting, particularly with regard to correctly interpreting diagnostic imaging procedures. The authors were selected from the members of the Neuroimaging Committee of the EANM and have extensive experience as clinicians and teachers within the Nuclear Medicine Community.
| Author | : Philip V. Peplow |
| Publisher | : |
| Total Pages | : 565 |
| Release | : 2021 |
| Genre | : Biochemical markers |
| ISBN | : 9781071617120 |
This volume presents recent data on the latest achievements in new and emerging technologies for biomarkers and for innovations in their assessment. The chapters cover topics such as activation of microglia and macrophages in neurodegenerative diseases; oxidative stress and cellular dysfunction in neurodegenerative diseases; TSPO PET imaging as a biomarker of neuroinflammation in neurodegenerative disorders; and imaging biomarkers in Huntington's disease and amyotrophic lateral sclerosis. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and comprehensive, Neurodegenerative Diseases Biomarkers: Towards Translating Research to Clinical Practice is a valuable resource for both experimental and clinical experts in the field of neurodegenerative diseases who are looking to expand their knowledge of novel biomarkers in different types of neurodegenerative diseases.
| Author | : R. Duncan |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 202 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 9401153981 |
In the developed world, images of brain structure are available as an everyday diagnostic aid, and the characteristic appearances of most pathological conditions can be looked up in a textbook. Functional brain imaging is to this day less widely used, partly because most pressing diagnostic questions can be answered by refer ence to the patient's cerebral anatomy, partly for reasons of technical limitations of functional techniques. PET as a technique is sufficiently resource-demanding and complex to inhibit its use as an everyday diagnostic technique. SPECT lacked suitable tracers for many years, and early systems had poor spatial resolution. However, rotating gamma camera technology has advanced to the point where images of the brain of reasonable quality can be obtained at most large hospitals, and practical tracers, particularly of regional cerebral blood flow, are easily avail able. As research advances, clinical applications are emerging. A recent report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology! details a number of currently recognised clinical appli cations, some of which are dealt with in this book. Given this recognition, it is increasingly important that clinicians (particularly neuroclinicians, psychiatrists and specialists in cerebrovascular disease), nuclear medicine specialists and physicists acquire an idea of the major applications of the technique, and the research background on which these applications are based.
