Molecular Advancements in Tropical Diseases Drug Discovery

Molecular Advancements in Tropical Diseases Drug Discovery
Author: Gauri Misra
Publisher: Academic Press
Total Pages: 156
Release: 2020-05-12
Genre: Science
ISBN: 0128213973

Molecular Advancements in Tropical Diseases Drug Discovery presents in-depth knowledge relating to the detection of infection, epidemiology, drugs against various tropical diseases, new target sites for drug discovery and multidrug resistance issues using bioinformatics tools and approaches. The book's chapters are written by experts in their respective fields so that each disease is covered in a rational manner and with a solid foundation on existing facts and prospective research ideas. - Updates knowledge about tropical diseases with recent advancements in the field - Presents an overview of new research covering detection, infection, epidemiology and risk factors of the most common tropical diseases using bioinformatics tools - Encompasses a detailed description of developments in drug discovery, new drugs and their molecular mechanisms of action

Design of Hybrid Molecules for Drug Development

Design of Hybrid Molecules for Drug Development
Author: Michael Decker
Publisher: Elsevier
Total Pages: 354
Release: 2017-04-05
Genre: Science
ISBN: 0081011180

Design of Hybrid Molecules for Drug Development reviews the principles, advantages, and limitations involved with designing these groundbreaking compounds. Beginning with an introduction to hybrid molecule design and background as to their need, the book goes on to explore a range of important hybrids, with hybrids containing natural products, molecules containing NO- and H2S-donors, dual-acting compounds acting as receptor ligands and enzyme inhibitors, and the design of photoresponsive drugs all discussed. Drawing on practical case studies, the hybridization of molecules for development as treatments for a number of key diseases is then outlined, including the design of hybrids for Alzheimer's, cancer, and malaria. With its cutting-edge reviews of breaking developments in this exciting field, the book offers a novel approach for all those working in the design, development, and administration of drugs for a range of debilitating disorders. - Highlights an approach unimpaired by the limitations of the classical search for lead structures - one of the core problems in modern drug development processes, making the content of high relevance for both academic and non-academic drug development processes - Pulls together research and design techniques in a novel way to give researchers the best possible platform from which to review the approaches and techniques applied - Compares the advantages and disadvantages of these compounds - Includes the very latest developments, such as photoactivatable and photo-responsive drugs

Travelers' Malaria

Travelers' Malaria
Author: Patricia Schlagenhauf-Lawlor
Publisher: PMPH-USA
Total Pages: 428
Release: 2008
Genre: Medical
ISBN: 9781550093360

Travelers' Malaria is considered an essential resource for practitioners of travel medicine. This updated book focuses on the epidemiology, prevention and treatment of malaria in non-immune travelers and immigrants. Each chapter is an up-to-date monograph (with an abstract) and contains detailed references to published literature as well as to appropriate web sites. The purpose of the book is to serve as a reference for specialists in the field and for any practitioner who may confront the complexities of caring for malaria-exposed travelers in both pre- and post-travel settings.Travelers' Malaria contains 26 chapters.

Malaria

Malaria
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 312
Release: 1991-02-01
Genre: Medical
ISBN: 9780309045278

Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities. The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the: Nature, clinical manifestations, diagnosis, and epidemiology of malaria. Biology of the malaria parasite and its vector. Prospects for developing malaria vaccines and improved treatments. Economic, social, and behavioral factors in malaria control.

Disease Control Priorities, Third Edition (Volume 6)

Disease Control Priorities, Third Edition (Volume 6)
Author: King K. Holmes
Publisher: World Bank Publications
Total Pages: 1027
Release: 2017-11-06
Genre: Medical
ISBN: 1464805253

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Reactive Oxygen Species

Reactive Oxygen Species
Author: Harald H. H. W. Schmidt
Publisher: Springer Nature
Total Pages: 425
Release: 2021-02-23
Genre: Medical
ISBN: 3030685101

Reactive oxygen species (ROS) have been implicated in almost every human disease phenotype, without much, if any, therapeutic consequence foremost exemplified by the failure of the so-called anti-oxidants. This book is a game changer for the field and many clinical areas such as cardiology and neurology. The term ‘oxidative stress’ is abandoned and replaced with a systems medicine and network pharmacology-based mechanistic approach to disease. The ROS-related drugs discussed here target either ROS- forming or ROS -modifying enzymes for which there is strong clinical evidence. In addition, ROS targets are included as they jointly participate in causal mechanisms of disease. This approach is transforming the ROS field and represents a breakthrough in redox medicine indicating a path to patient benefit. In the coming years more targets and drugs may be discovered, but the approach will remain the same and this book will thus become, and for many years remain, the leading reference for ROSopathies and their treatment by network pharmacology. Chapter "Soluble Guanylate Cyclase Stimulators and Activators" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Pathogenesis, Treatment and Prevention of Leishmaniasis

Pathogenesis, Treatment and Prevention of Leishmaniasis
Author: Mukesh Samant
Publisher: Academic Press
Total Pages: 281
Release: 2021-08-18
Genre: Medical
ISBN: 0128227982

Leishmaniasis is a neglected tropical disease that is known to be transmitted by 90 different species of sandflies which carry 20 Leishmania species that cause human infection particularly in endemic countries. Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to provide information on this vector-borne disease and explore strategies for diagnosis and treatment. The book begins with an overview of leishmaniasis which includes historical and future perspectives of the disease. It also discusses the clinical manifestation of the disease, mechanisms of infection, therapeutic strategies, diagnostics, prevention, and cure of Leishmania parasite. The book goes on to explain new insights and challenges in the development of promising drug targets, biomarkers identification and advance vaccination strategies against leishmaniasis. Chapter contributions brings together diverse areas of expertise making Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to bring together elements of leishmaniasis into one place and be a valuable resource for researchers, health care professionals, and graduate students, working in the field of leishmaniasis. - Provides an overview Leishmania and leishmanisis which include its history, transmission, clinical picture, and treatment - Discusses novel approaches to study parasite infection and treatment - Explores recent advances in the development of diagnostic kits, drug development and various vaccination strategies

Proceedings of 4th International Conference and Business Expo on Wireless, Telecommunication & IoT 2018

Proceedings of 4th International Conference and Business Expo on Wireless, Telecommunication & IoT 2018
Author: ConferenceSeries
Publisher: ConferenceSeries
Total Pages: 82
Release:
Genre:
ISBN:

July 19-20, 2018 at London, UK Key Topics : 5G and Beyond, Wireless Communication, Telecommunication, Internet of Things (IoT), Cloud Computing, Technology for Wireless, Ad Hoc and Sensors Networks, Mobile and Wireless Network, Satellite Communication, Space Communications and Navigation, 3G & 4G, Big Data, Artificial Intelligence,

Proceedings of 4th Global Summit and Expo on Multimedia & Artificial Intelligence 2018

Proceedings of 4th Global Summit and Expo on Multimedia & Artificial Intelligence 2018
Author: ConferenceSeries
Publisher: ConferenceSeries
Total Pages: 92
Release:
Genre:
ISBN:

July 19-21, 2018 Rome, Italy Key Topics : Imaging and Image Processing, Multimedia Cloud and Big Data, Multimedia IoT, Multimedia Systems & Services, Computer Games Design & Development, Multimedia Applications, Computer Graphics & Animation, Compter Vision and Pattern Recognition, Virtual Reality & Augmented Reality, Artificial Intelligence & Machine Learning, Natural language processing & Tensorflow, Artificial Intelligence for Bussines, Neural Networks, Human Computer Interaction and Visualization, Artificial Intelligence & Multimedia Technologies in Healthcare,