Modified Mass-spring System for Physically Based Deformation Modeling

Modified Mass-spring System for Physically Based Deformation Modeling
Author: Oussama Jarrousse
Publisher: KIT Scientific Publishing
Total Pages: 244
Release: 2014-09
Genre: Technology & Engineering
ISBN: 3866447426

Mass-spring systems are considered the simplest and most intuitive of all deformable models. They are computationally efficient, and can handle large deformations with ease. But they suffer several intrinsic limitations. In this book a modified mass-spring system for physically based deformation modeling that addresses the limitations and solves them elegantly is presented. Several implementations in modeling breast mechanics, heart mechanics and for elastic images registration are presented.

The Politics of Belonging in Contemporary India

The Politics of Belonging in Contemporary India
Author: Kaustav Chakraborty
Publisher: Routledge India
Total Pages: 0
Release: 2019-07-02
Genre: Social Science
ISBN: 9781000024302

This volume looks at the emerging forms of intimacies in contemporary India. Drawing on rigorous academic research and pop culture phenomena, the volume: Brings together themes of nationhood, motherhood, disability, masculinity, ethnicity, kinship, and sexuality, and attempts to understand them within a more complex web of issues related to space, social justice, marginality, and communication; Focuses on the struggles for intimacy by the disabled, queer, Dalit, and other subalterns, as well as people with non-human intimacies, to propose an alternative theory of the politics of belonging; Explores the role of social and new media in understanding and negotiating intimacies and anxieties. Comprehensive and thought-provoking, this book will be useful to scholars and researchers of political studies, sociology, sexuality and gender studies, women’s studies, cultural studies, and minority studies.

Personalized Multi-Scale Modeling of the Atria: Heterogeneities, Fiber Architecture, Hemodialysis and Ablation Therapy

Personalized Multi-Scale Modeling of the Atria: Heterogeneities, Fiber Architecture, Hemodialysis and Ablation Therapy
Author: Martin Wolfgang Krüger
Publisher: KIT Scientific Publishing
Total Pages: 320
Release: 2014-05-22
Genre: Technology & Engineering
ISBN: 3866449488

This book targets three fields of computational multi-scale cardiac modeling. First, advanced models of the cellular atrial electrophysiology and fiber orientation are introduced. Second, novel methods to create patient-specific models of the atria are described. Third, applications of personalized models in basic research and clinical practice are presented. The results mark an important step towards the patient-specific model-based atrial fibrillation diagnosis, understanding and treatment.

Modeling Human Atrial Patho-Electrophysiology from Ion Channels to ECG - Substrates, Pharmacology, Vulnerability, and P-Waves

Modeling Human Atrial Patho-Electrophysiology from Ion Channels to ECG - Substrates, Pharmacology, Vulnerability, and P-Waves
Author: Loewe, Axel
Publisher: KIT Scientific Publishing
Total Pages: 342
Release: 2016-08-03
Genre: Technology (General)
ISBN: 3731505282

Half of the patients suffering from atrial fibrillation (AF) cannot be treated adequately, today. This book presents multi-scale computational methods to advance our understanding of patho-mechanisms, to improve the diagnosis of patients harboring an arrhythmogenic substrate, and to tailor therapy. The modeling pipeline ranges from ion channels on the subcellular level up to the ECG on the body surface. The tailored therapeutic approaches carry the potential to reduce the burden of AF.

Multiscale Modeling of Cardiac Electrophysiology: Adaptation to Atrial and Ventricular Rhythm Disorders and Pharmacological Treatment

Multiscale Modeling of Cardiac Electrophysiology: Adaptation to Atrial and Ventricular Rhythm Disorders and Pharmacological Treatment
Author: Mathias Wilhelms
Publisher: KIT Scientific Publishing
Total Pages: 206
Release: 2014-05-22
Genre: Technology & Engineering
ISBN: 3731500450

Multiscale modeling of cardiac electrophysiology helps to better understand the underlying mechanisms of atrial fibrillation, acute cardiac ischemia and pharmacological treatment. For this purpose, measurement data reflecting these conditions have to be integrated into models of cardiac electrophysiology. Several methods for this model adaptation are introduced in this thesis. The resulting effects are investigated in multiscale simulations ranging from the ion channel up to the body surface.AbstractEnglisch = Multiscale modeling of cardiac electrophysiology helps to better understand the underlying mechanisms of atrial fibrillation, acute cardiac ischemia and pharmacological treatment. For this purpose, measurement data reflecting these conditions have to be integrated into models of cardiac electrophysiology. Several methods for this model adaptation are introduced in this thesis. The resulting effects are investigated in multiscale simulations ranging from the ion channel up to the body surface.

Multiscale Cohort Modeling of Atrial Electrophysiology : Risk Stratification for Atrial Fibrillation through Machine Learning on Electrocardiograms

Multiscale Cohort Modeling of Atrial Electrophysiology : Risk Stratification for Atrial Fibrillation through Machine Learning on Electrocardiograms
Author: Nagel, Claudia
Publisher: KIT Scientific Publishing
Total Pages: 280
Release: 2023-04-24
Genre:
ISBN: 3731512815

An early detection and diagnosis of atrial fibrillation sets the course for timely intervention to prevent potentially occurring comorbidities. Electrocardiogram data resulting from electrophysiological cohort modeling and simulation can be a valuable data resource for improving automated atrial fibrillation risk stratification with machine learning techniques and thus, reduces the risk of stroke in affected patients.

ECG Based Analysis of the Ventricular Repolarisation in the Human Heart

ECG Based Analysis of the Ventricular Repolarisation in the Human Heart
Author: Baas, Tobias
Publisher: KIT Scientific Publishing
Total Pages: 260
Release: 2012-08-06
Genre: Technology & Engineering
ISBN: 3866448821

ECG recordings provide diagnostic relevant information on the de- and repolarisation sequences of the heart. A modification of the repolarisation sequence is assumed to cause Torsades de Pointes. Especially drug induced effects on the repolarisation processes are in focus, since some non-cardiac drugs have been associated with sudden cardiac death in the 1990s.The analysis of the ventricular repolarisation using a set of parameters depicting the morphology of the T-wave is introduced in this work. Therefore, new methods of fully automatic patient-specific QRS detection, beat classification and precise T-wave delineation are presented. Using these methods, medical studies are investigated regarding the modification of the T-wave by different compounds. Also the impact of the heart rate on the morphology of the T-wave is part of this research.The reliable identification of ventricular ectopic beats allows an analysis of the influence of these beats on subsequent heart beats. It turned out that the morphology of subsequent heart beats can significantly be changed. This might give new information on the proarrythmical risk of ventricular ectopic beats.

Analysis of Atrial Electrograms

Analysis of Atrial Electrograms
Author: Christopher Schilling
Publisher: KIT Scientific Publishing
Total Pages: 240
Release: 2012
Genre: Atrial fibrillation
ISBN: 3866448945

This work provides methods to measure and analyze features of atrial electrograms - especially complex fractionated atrial electrograms (CFAEs) - mathematically. Automated classification of CFAEs into clinical meaningful classes is applied and the newly gained electrogram information is visualized on patient specific 3D models of the atria. Clinical applications of the presented methods showed that quantitative measures of CFAEs reveal beneficial information about the underlying arrhythmia.

Formation of Intracardiac Electrograms under Physiological and Pathological Conditions

Formation of Intracardiac Electrograms under Physiological and Pathological Conditions
Author: Keller, Matthias
Publisher: KIT Scientific Publishing
Total Pages: 264
Release: 2014-09-09
Genre: Technology & Engineering
ISBN: 3731502283

This work presents methods to advance electrophysiological simulations of intracardiac electrograms (IEGM). An experimental setup is introduced, which combines electrical measurements of extracellular potentials with a method for optical acquisition of the transmembrane voltage in-vitro. Thereby, intracardiac electrograms can be recorded under defined conditions. Using experimental and clinical signals, detailed simulations of IEGMs are parametrized, which can support clinical diagnosis.