Modelling Protocells
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| Author | : Roberto Serra |
| Publisher | : Springer |
| Total Pages | : 191 |
| Release | : 2017-07-24 |
| Genre | : Science |
| ISBN | : 9402411607 |
The monograph discusses models of synthetic protocells, which are cell-like structures obtained from non-living matter endowed with some rudimentary kind of metabolism and genetics, but much simpler than biological cells. They should grow and proliferate, generating offsprings that resemble in some way the parent protocells with some variation, so that selection may take place. Sustainable protocell populations have not yet been obtained experimentally and mathematical models are therefore extremely important to address key questions concerning their synthesis and behavior. Different protocell “architectures” have been proposed and high-level abstract models like those that are presented in this book are particularly relevant to gain a better understanding of the different properites. These models are able to treat all the major dynamical phenomena in a unified framework, so they can be seen as “virtual laboratories” for protocell research. Particular attention is paid to the problem of synchronization of the fission rate of the whole protocell and the duplication rate of its "protogenetic" material, which is shown to be an emergent property that spontaneously develops in successive generations. The book is of interest for a broad range of scientists working in soft matter physics, chemistry and biology, interested in the role protocells may play on the development of new technologies with medical, environmental and industrial applications as well as scientists interested in the origin of life.
| Author | : Steen Rasmussen |
| Publisher | : MIT Press |
| Total Pages | : 723 |
| Release | : 2022-06-07 |
| Genre | : Science |
| ISBN | : 0262545888 |
The first comprehensive general resource on state-of-the-art protocell research, describing current approaches to making new forms of life from scratch in the laboratory. Protocells offers a comprehensive resource on current attempts to create simple forms of life from scratch in the laboratory. These minimal versions of cells, known as protocells, are entities with lifelike properties created from nonliving materials, and the book provides in-depth investigations of processes at the interface between nonliving and living matter. Chapters by experts in the field put this state-of-the-art research in the context of theory, laboratory work, and computer simulations on the components and properties of protocells. The book also provides perspectives on research in related areas and such broader societal issues as commercial applications and ethical considerations. The book covers all major scientific approaches to creating minimal life, both in the laboratory and in simulation. It emphasizes the bottom-up view of physicists, chemists, and material scientists but also includes the molecular biologists' top-down approach and the origin-of-life perspective. The capacity to engineer living technology could have an enormous socioeconomic impact and could bring both good and ill. Protocells promises to be the essential reference for research on bottom-up assembly of life and living technology for years to come. It is written to be both resource and inspiration for scientists working in this exciting and important field and a definitive text for the interested layman.
| Author | : Peter Walde |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 248 |
| Release | : 2005-10-13 |
| Genre | : Science |
| ISBN | : 9783540277590 |
| Author | : Marcello Pelillo |
| Publisher | : Springer |
| Total Pages | : 326 |
| Release | : 2018-04-02 |
| Genre | : Computers |
| ISBN | : 331978658X |
This book constitutes the revised selected papers of the 12th Italian Workshop on Advances in Artificial Life, Evolutionary Computation, WIVACE 2017, held in Venice, Italy, in September 2017.The 23 full papers presented were thoroughly reviewed and selected from 33 submissions. They cover the following topics: physical-chemical phenomena; biological systems; economy and society; complexity; optimization.
| Author | : Joseph Seckbach |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 911 |
| Release | : 2012-03-19 |
| Genre | : Science |
| ISBN | : 9400729413 |
Genesis – In The Beginning deals with the origin and diversity of Life and early biological evolution and discusses the question of where (hot or cold sources) and when the beginning of Life took place. Among the sections are chapters dealing with prebiotic chemical processes and considering self-replication of polymers in mineral habitats. One chapter is dedicated to the photobiological regime on early Earth and the emergence of Life. This volume covers the role of symmetry, information and order (homochrial biomolecules) in the beginning of Life. The models of protocells and the genetic code with gene transfer are important topics in this volume. Three chapters discuss the Panspermia hypothesis (to answer “Are we from outer Space?”). Other chapters cover the Astrobiological aspects of Life in the Universe in extraterrestrial Planets of the Solar System and deal with cometary hydrosphere (and its connection to Earth). We conclude with the history and frontiers of Astrobiogy.
| Author | : Claudio De Stefano |
| Publisher | : Springer Nature |
| Total Pages | : 314 |
| Release | : 2023-04-29 |
| Genre | : Computers |
| ISBN | : 3031311833 |
This book constitutes the refereed proceedings of the 16th Italian Workshop on Artificial Life and Evolutionary Computation, WIVACE 2022, held in Gaeta, Italy, during September 14–16, 2022. The 21 full papers and 3 short papers included in this book were carefully reviewed and selected from 45 submissions. They were organized in topical sections as follows: answer set programming; networks and complex systems, metaheuristics, robotics, and machine learning Chapters 7, 8, and 9 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
| Author | : Juan Bueno |
| Publisher | : Academic Press |
| Total Pages | : 194 |
| Release | : 2020-01-22 |
| Genre | : Medical |
| ISBN | : 0128189290 |
Molecular Evolutionary Models in Drug Discovery explores the application of evolutionary molecular models in drug discovery in which secondary metabolites play a fundamental role. Secondary metabolites are not produced in isolation, they are the result of the interaction of genes, metabolism and the environment. The book examines the role of secondary metabolites as leads in drug discovery and on the development of a rational bioprospecting model for new medicines based on the evolution of secondary metabolism. These evolutionary models are part of biological systems and are the most reliable expression of the functioning of living beings. - Examines the integration and application of evolutionary models in the pharmaceutical industry to create new drug development platforms - Investigates the biotechnological prospecting of secondary metabolites and their potential use in the discovery of new drugs - Evaluates the ecosystem of living beings and how its molecular adaptation might improve the success of therapies
| Author | : Ricardo Amils |
| Publisher | : Springer |
| Total Pages | : 1853 |
| Release | : 2021-01-14 |
| Genre | : Science |
| ISBN | : 9783642278334 |
The interdisciplinary field of Astrobiology constitutes a joint arena where provocative discoveries are coalescing concerning, e.g. the prevalence of exoplanets, the diversity and hardiness of life, and its increasingly likely chances for its emergence. Biologists, astrophysicists, biochemists, geoscientists and space scientists share this exciting mission of revealing the origin and commonality of life in the Universe. The members of the different disciplines are used to their own terminology and technical language. In the interdisciplinary environment many terms either have redundant meanings or are completely unfamiliar to members of other disciplines. The Encyclopedia of Astrobiology serves as the key to a common understanding. Each new or experienced researcher and graduate student in adjacent fields of astrobiology will appreciate this reference work in the quest to understand the big picture. The carefully selected group of active researchers contributing to this work and the expert field editors intend for their contributions, from an internationally comprehensive perspective, to accelerate the interdisciplinary advance of astrobiology.
| Author | : Stoyan K. Smoukov |
| Publisher | : John Wiley & Sons |
| Total Pages | : 516 |
| Release | : 2023-03-21 |
| Genre | : Science |
| ISBN | : 1119555523 |
Conflicting Models for the Origin of Life Conflicting Models for the Origin of Life provides a forum to compare and contrast the many hypotheses that have been put forward to explain the origin of life. There is a revolution brewing in the field of Origin of Life: in the process of trying to figure out how Life started, many researchers believe there is an impending second creation of life, not necessarily biological. Up-to-date understanding is needed to prepare us for the technological, and societal changes it would bring. Schrodinger’s 1944 “What is life?” included the insight of an information carrier, which inspired the discovery of the structure of DNA. In “Conflicting Models of the Origin of Life” a selection of the world’s experts are brought together to cover different aspects of the research: from progress towards synthetic life – artificial cells and sub-cellular components, to new definitions of life and the unexpected places life could (have) emerge(d). Chapters also cover fundamental questions of how memory could emerge from memoryless processes, and how we can tell if a molecule may have emerged from life. Similarly, cutting-edge research discusses plausible reactions for the emergence of life both on Earth and on exoplanets. Additional perspectives from geologists, philosophers and even roboticists thinking about the origin of life round out this volume. The text is a state-of-the-art snapshot of the latest developments on the emergence of life, to be used both in graduate classes and by citizen scientists. Audience Researchers in any area of astrobiology, as well as others interested in the origins of life, will find a modern and current review of the field and the current debates and obstacles. This book will clearly illustrate the current state-of-the-art and engage the imagination and creativity of experts across many disciplines.
| Author | : Arantza Etxeberria |
| Publisher | : Frontiers Media SA |
| Total Pages | : 228 |
| Release | : 2021-08-18 |
| Genre | : Science |
| ISBN | : 2889711927 |
