Microsystems for Enhanced Control of Cell Behavior

Microsystems for Enhanced Control of Cell Behavior
Author: Andrés Díaz Lantada
Publisher: Springer
Total Pages: 457
Release: 2016-03-23
Genre: Technology & Engineering
ISBN: 3319293281

This handbook focuses on the entire development process of biomedical microsystems that promote special interactions with cells. Fundamentals of cell biology and mechanobiology are described as necessary preparatory input for design tasks. Advanced design, simulation, and micro/nanomanufacturing resources, whose combined use enables the development of biomedical microsystems capable of interacting at a cellular level, are covered in depth. A detailed series of chapters is then devoted to applications based on microsystems that offer enhanced cellular control, including microfluidic devices for diagnosis and therapy, cell-based sensors and actuators (smart biodevices), microstructured prostheses for improvement of biocompatibility, microstructured and microtextured cell culture matrices for promotion of cell growth and differentiation, electrophoretic microsystems for study of cell mechanics, microstructured and microtextured biodevices for study of cell adhesion and dynamics, and biomimetic microsystems (including organs-on-chips), among others. Challenges relating to the development of reliable in vitro biomimetic microsystems, the design and manufacture of complex geometries, and biofabrication are also discussed.

3D Bioprinting in Regenerative Engineering

3D Bioprinting in Regenerative Engineering
Author: Ali Khademhosseini
Publisher: CRC Press
Total Pages: 279
Release: 2018-04-17
Genre: Technology & Engineering
ISBN: 1315280477

Regenerative engineering is the convergence of developmental biology, stem cell science and engineering, materials science, and clinical translation to provide tissue patches or constructs for diseased or damaged organs. Various methods have been introduced to create tissue constructs with clinically relevant dimensions. Among such methods, 3D bioprinting provides the versatility, speed and control over location and dimensions of the deposited structures. Three-dimensional bioprinting has leveraged the momentum in printing and tissue engineering technologies and has emerged as a versatile method of fabricating tissue blocks and patches. The flexibility of the system lies in the fact that numerous biomaterials encapsulated with living cells can be printed. This book contains an extensive collection of papers by world-renowned experts in 3D bioprinting. In addition to providing entry-level knowledge about bioprinting, the authors delve into the latest advances in this technology. Furthermore, details are included about the different technologies used in bioprinting. In addition to the equipment for bioprinting, the book also describes the different biomaterials and cells used in these approaches. This text: Presents the principles and applications of bioprinting Discusses bioinks for 3D printing Explores applications of extrusion bioprinting, including past, present, and future challenges Includes discussion on 4D Bioprinting in terms of mechanisms and applications

Microdevices and Microsystems for Cell Manipulation

Microdevices and Microsystems for Cell Manipulation
Author: Aaron T. Ohta
Publisher: MDPI
Total Pages: 179
Release: 2018-07-03
Genre: Science
ISBN: 3038426180

This book is a printed edition of the Special Issue "Microdevices and Microsystems for Cell Manipulation" that was published in Micromachines

Micro and Nanoengineering of the Cell Microenvironment

Micro and Nanoengineering of the Cell Microenvironment
Author: Ali Khademhosseini
Publisher: Artech House
Total Pages: 647
Release: 2008
Genre: Science
ISBN: 1596931493

Supported with 140 illustrations, the volume exhaustively covers the micro- and nano-system technologies involved in developing cell-based bioengineering applications. You get full details on efforts to engineer the soluble and insoluble cell microenvironments, including the latest advances in microfluidic devices, surface patterning, 3D scaffolds, and techniques for engineering cellular mechanical properties and topography.

Integrated Microsystems

Integrated Microsystems
Author: Krzysztof Iniewski
Publisher: CRC Press
Total Pages: 760
Release: 2017-12-19
Genre: Medical
ISBN: 1439836213

As rapid technological developments occur in electronics, photonics, mechanics, chemistry, and biology, the demand for portable, lightweight integrated microsystems is relentless. These devices are getting exponentially smaller, increasingly used in everything from video games, hearing aids, and pacemakers to more intricate biomedical engineering and military applications. Edited by Kris Iniewski, a revolutionary in the field of advanced semiconductor materials, Integrated Microsystems: Electronics, Photonics, and Biotechnology focuses on techniques for optimized design and fabrication of these intelligent miniaturized devices and systems. Composed of contributions from experts in academia and industry around the world, this reference covers processes compatible with CMOS integrated circuits, which combine computation, communications, sensing, and actuation capabilities. Light on math and physics, with a greater emphasis on microsystem design and configuration and electrical engineering, this book is organized in three sections—Microelectronics and Biosystems, Photonics and Imaging, and Biotechnology and MEMs. It addresses key topics, including physical and chemical sensing, imaging, smart actuation, and data fusion and management. Using tables, figures, and equations to help illustrate concepts, contributors examine and explain the potential of emerging applications for areas including biology, nanotechnology, micro-electromechanical systems (MEMS), microfluidics, and photonics.

Biomaterials

Biomaterials
Author: Joyce Y. Wong
Publisher: CRC Press
Total Pages: 293
Release: 2007-06-07
Genre: Medical
ISBN: 0849378893

For medical devices that must be placed inside the body, the right choice of material is the most important aspect of design. To ensure such devices are safe, reliable, economical, and biologically and physiologically compatible, the modern biomedical engineer must have a broad knowledge of currently available materials and the properties that affe

Cardiac Cell Culture Technologies

Cardiac Cell Culture Technologies
Author: Zbigniew Brzozka
Publisher: Springer
Total Pages: 245
Release: 2017-11-21
Genre: Technology & Engineering
ISBN: 3319706853

This book provides an introduction to the biological background of heart functioning and analyzes the various materials and technologies used for the development of microfluidic systems dedicated to cell culture, with an emphasis on cardiac cells. The authors describe the characterization of microfluidic systems for cardiac cell culture and center their discussion of the use of stem cell stimulation based on four different types: electrical, biochemical, physical, and mechanical. This book is appropriate for researchers focused on on-chip technologies and heart studies, students in bioengineering and microengineering courses, and a variety of professionals, such as biotechnologists, biomedical engineers, and clinicians working in the cardiac diseases field.

Brain-Computer Interfaces

Brain-Computer Interfaces
Author: Theodore W. Berger
Publisher: Springer Science & Business Media
Total Pages: 310
Release: 2008-09-18
Genre: Technology & Engineering
ISBN: 1402087055

We have come to know that our ability to survive and grow as a nation to a very large degree depends upon our scientific progress. Moreover, it is not enough simply to keep 1 abreast of the rest of the world in scientific matters. We must maintain our leadership. President Harry Truman spoke those words in 1950, in the aftermath of World War II and in the midst of the Cold War. Indeed, the scientific and engineering leadership of the United States and its allies in the twentieth century played key roles in the successful outcomes of both World War II and the Cold War, sparing the world the twin horrors of fascism and totalitarian communism, and fueling the economic prosperity that followed. Today, as the United States and its allies once again find themselves at war, President Truman’s words ring as true as they did a half-century ago. The goal set out in the Truman Administration of maintaining leadership in science has remained the policy of the U. S. Government to this day: Dr. John Marburger, the Director of the Office of Science and Technology (OSTP) in the Executive Office of the President, made remarks to that effect during his 2 confirmation hearings in October 2001. The United States needs metrics for measuring its success in meeting this goal of maintaining leadership in science and technology. That is one of the reasons that the National Science Foundation (NSF) and many other agencies of the U. S.

Biomedical Microsystems

Biomedical Microsystems
Author: Ellis Meng
Publisher: CRC Press
Total Pages: 410
Release: 2011-06-22
Genre: Medical
ISBN: 1420051237

Poised to dramatically impact human health, biomedical microsystems (bioMEMS) technologies incorporate various aspects from materials science, biology, chemistry, physics, medicine, and engineering. Reflecting the highly interdisciplinary nature of this area, Biomedical Microsystems covers the fundamentals of miniaturization, biomaterials, microfabrication, and nanotechnology, along with relevant applications. Written by an active researcher who was recently named one of Technology Review’s Young Innovators Under 35, the book begins with an introduction to the benefits of miniaturization. It then introduces materials, fabrication technology, and the necessary components of all bioMEMS. The author also covers fundamental principles and building blocks, including microfluidic concepts, lab-on-a-chip systems, and sensing and detection methods. The final chapters explore several important applications of bioMEMS, such as microdialysis, catheter-based sensors, MEMS implants, neural probes, and tissue engineering. For readers with a limited background in MEMS and bioMEMS, this book provides a practical introduction to the technology used to make these devices, the principles that govern their operation, and examples of their application. It offers a starting point for understanding advanced topics and encourages readers to begin to formulate their own ideas about the design of novel bioMEMS. A solutions manual is available for instructors who want to convert this reference to classroom use.

Nanoarchitectonics in Biomedicine

Nanoarchitectonics in Biomedicine
Author: Alexandru Mihai Grumezescu
Publisher: William Andrew
Total Pages: 724
Release: 2019-03-20
Genre: Science
ISBN: 0128172614

Nanoarchitectonics in Biomedicine describes this new area of nanoscience that has emerged as a major branch of nanoscience. The book brings together recent applications and discusses the advantages and disadvantages of each process, offering international perspectives on the technologies based on these findings. It offers new insights for nanoarchitectonics, starting with the currently used methods of synthesis and characterization of such materials, along with their biomedical applications. Authored by a wide range of international scientists, this volume shows how nanoarchitectonics is being used to create more efficient medical treatment solutions. Users will find this to be an important research resource for those wanting to learn more on the emerging topic of nanoarchitectonics in biomedical science. - Explores how design aspects, smart materials and personalized materials are used in biomedicine today - Offers global perspectives on how nanoarchitectonics is used in different regions - Presents an important research resource for those wanting to learn more on the emerging topic of nanoarchitectonics in biomedical science