Methods in Radioimmunoassay, Toxicology, and Related Areas
Author | : Ivor L. Simmons |
Publisher | : Springer Science & Business Media |
Total Pages | : 188 |
Release | : 2013-11-11 |
Genre | : Science |
ISBN | : 1468433210 |
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Author | : Ivor L. Simmons |
Publisher | : Springer Science & Business Media |
Total Pages | : 188 |
Release | : 2013-11-11 |
Genre | : Science |
ISBN | : 1468433210 |
Author | : Carlo Patrono |
Publisher | : Springer Science & Business Media |
Total Pages | : 625 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 3642718094 |
Thirty years have elapsed since the first description by S. A. BERSON and R. S. Y ALOW of the basic principles of radioimmunoassay (RIA). During this period of time, RIA methodology has been instrumental to the growth of many areas of biomedical research, including endocrinology, oncology, hematology, and pharmacology. It has done so by providing a relatively simple universal tool allowing, for the first time, the detection of endogenous mediators that are present 12 10 in body fluids at concentrations as low as 10- _10- M. The fundamental nature of this discovery and the wide-ranging fall-out of basic and clinical knowledge derived from its application have been acknowledged by the many honors tributed to its pioneers, including the Nobel Prize awarded to Dr. Y ALOW 10 years ago. Although several excellent books have been published during the past decades covering various aspects of RIA methodology, we felt the need, as pharmacologists, for a comprehensive discussion of the methodological and conceptual issues related to the main classes of mediators of drug action and to drugs themselves. Thus, we gladly accepted the challenge provided by the invitation to edit a volume of the Handbook of Experimental Pharmacology on Radioimmunoassay in Basic and Clinical Pharmacology. We tried to balance the emphasis placed on more general aspects of the RIA methodology and that on specific mediators.
Author | : Guoqiao Li |
Publisher | : Academic Press |
Total Pages | : 738 |
Release | : 2017-11-28 |
Genre | : Science |
ISBN | : 0128132116 |
Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It is a valuable reference for students and researchers in the fields of scientific history, medicine, pharmaceutical science, chemistry, pharmacology and toxicology. - Presents details of all stages of drug development, including in vitro experiment, animal exploratory studies, animal tests for toxicity, safety and efficacy followed by stages I, II, III and IV, safety and efficacy in human volunteers and patients with malaria - Provides many physical-chemical laboratory procedures, such as NMR, MS, HPLC and X-ray diffraction used in drug development - Includes practical methodology of clinical trials from many research centers and countries to demonstrate the importance of this discovery
Author | : National Library of Medicine (U.S.) |
Publisher | : |
Total Pages | : |
Release | : 1971 |
Genre | : Medicine |
ISBN | : |
First multi-year cumulation covers six years: 1965-70.
Author | : |
Publisher | : Academic Press |
Total Pages | : 2370 |
Release | : 2019-06-28 |
Genre | : Medical |
ISBN | : 0128127368 |
Encyclopedia of Pharmacy Practice and Clinical Pharmacy, Three Volume Set covers definitions, concepts, methods, theories and applications of clinical pharmacy and pharmacy practice. It highlights why and how this field has a significant impact on healthcare. The work brings baseline knowledge, along with the latest, most cutting-edge research. In addition, new treatments, algorithms, standard treatment guidelines, and pharmacotherapies regarding diseases and disorders are also covered. The book's main focus lies on the pharmacy practice side, covering pharmacy practice research, pharmacovigilance, pharmacoeconomics, social and administrative pharmacy, public health pharmacy, pharmaceutical systems research, the future of pharmacy, and new interventional models of pharmaceutical care. By providing concise expositions on a broad range of topics, this book is an excellent resource for those seeking information beyond their specific areas of expertise. This outstanding reference is essential for anyone involved in the study of pharmacy practice. Provides a ‘one-stop’ resource for access to information written by world-leading scholars in the field Meticulously organized, with articles split into three clear sections, it is the ideal resource for students, researchers and professionals to find relevant information Contains concise and accessible chapters that are ideal as an authoritative introduction for non-specialists and readers from the undergraduate level upwards Includes multimedia options, such as hyperlinked references and further readings, cross-references and videos
Author | : P. Hlavica |
Publisher | : Springer Science & Business Media |
Total Pages | : 487 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 9401131120 |
Author | : National Research Council |
Publisher | : National Academies Press |
Total Pages | : 204 |
Release | : 1989-02-01 |
Genre | : Science |
ISBN | : 9780309039901 |
Biologic markersâ€"indicators of biological exposure or changeâ€"offer the promise of early detection of disease caused by environmental exposure. Researchers have used these markers to discover indications of pulmonary damage from low-level ozone, a finding with serious implications for health professionals and environmental regulators. Biologic Markers in Pulmonary Toxicology is a comprehensive study of this use of biologic markers. Focusing on the respiratory tract as an entryway for airborne pollutants, this volume reviews new ways of measuring markers, the need for markers to indicate dose or exposure levels, noninvasive respiratory function tests for use with healthy humans to detect sensitivity to inhaled pollutants, approaches to evaluating markers down to the cellular and biochemical levels, and more.
Author | : |
Publisher | : |
Total Pages | : 500 |
Release | : 1995 |
Genre | : Polycyclic aromatic hydrocarbons |
ISBN | : |
Author | : Scripps Institution of Oceanography. Library |
Publisher | : |
Total Pages | : 980 |
Release | : 1980 |
Genre | : Marine biology |
ISBN | : |