Metabolomics: From Fundamentals to Clinical Applications

Metabolomics: From Fundamentals to Clinical Applications
Author: Alessandra Sussulini
Publisher: Springer
Total Pages: 353
Release: 2017-01-28
Genre: Science
ISBN: 3319476564

This book provides a comprehensive view of metabolomics, from the basic concepts, through sample preparation and analytical methodologies, to data interpretation and applications in medicine. It is the first volume to cover metabolomics clinical applications while also emphasizing analytical and statistical features. Moreover, future trends and perspectives in clinical metabolomics are also presented. For researches already experienced in metabolomics, the book will be useful as an updated definitive reference. For beginners in the field and graduate students, the book will provide detailed information about concepts and experimental aspects in metabolomics, as well as examples and perspectives of applications of this strategy to clinical questions.

Metabolomics

Metabolomics
Author: Jeevan Prasain
Publisher: BoD – Books on Demand
Total Pages: 218
Release: 2016-12-28
Genre: Science
ISBN: 9535128531

Metabolomics: Fundamentals and Applications authoritatively presents the basic principles and applications of metabolomics. Topics covered in this book range from the analysis of metabolites from different biological sources and their data processing and statistical analysis. This book serves as a basic guide for a wide range of audiences from less familiar with metabolomics techniques to more experienced researchers seeking to understand complex biological systems from the systems biology approach.

MALDI Mass Spectrometry Imaging

MALDI Mass Spectrometry Imaging
Author: Tiffany Siegel Porta
Publisher: Royal Society of Chemistry
Total Pages: 541
Release: 2021-12-03
Genre: Science
ISBN: 1839162414

This book gathers knowledge about matrix-assisted laser desorption ionisation (MALDI) mass spectrometry imaging for postgraduate and professional researchers in academia and in industry where it has direct application to clinical research.

Ion Mobility-Mass Spectrometry

Ion Mobility-Mass Spectrometry
Author: Alison E Ashcroft
Publisher: Royal Society of Chemistry
Total Pages: 621
Release: 2021-11-11
Genre: Science
ISBN: 1839162899

Over the last decade, the use of ion mobility separation in combination with mass spectrometry analysis has developed significantly. This technique adds a unique extra dimension enabling the in-depth analysis of a wide range of complex samples in the areas of the chemical and biological sciences. Providing a comprehensive guide to the technique, each chapter is written by an internationally recognised expert and with numerous different commercial platforms to choose from, this book will help the end users understand the practicalities of using different instruments for different ion mobility purposes. The first section provides a detailed account of the fundamentals behind the technique and the current range of available instrumentation. The second section focusses on the wide range of applications that have benefitted from ion mobility – mass spectrometry and includes topics taken from current research in the pharmaceutical, metabolomics, glycomics, and structural molecular biology fields. The book is primarily aimed at researchers, appealing to practising chemists and biochemists, as well as those in the pharmaceutical and medical fields.

Introduction and Application of Organic Fertilizers as Protectors of Our Environment

Introduction and Application of Organic Fertilizers as Protectors of Our Environment
Author: Munir Ozturk
Publisher: Cambridge Scholars Publishing
Total Pages: 530
Release: 2022-02-22
Genre: Business & Economics
ISBN: 1527580997

This book gives the latest information on advances in organic agriculture which can be used by agroindustry people as well as agricultural engineers and with practical examples for farmers. It provides important information covering multidisciplinary approaches on environmental awareness, organic agricultural production as well as organic fertilizers. The chapters here are prepared by experts in the field who present and discuss the principles of a wide range of practical ideas with examples. This book also presents novel ideas and suggestions for future research in organic agricultural production. The topics included in this book are based on surveys together with literature reviews to enable the academic and industrial readers to evaluate what they see as specific to their own discipline. The chapters include a wide range of topics which will also make it easy to make comparisons between different disciplines.

Methodologies for Metabolomics

Methodologies for Metabolomics
Author: Norbert W. Lutz
Publisher: Cambridge University Press
Total Pages: 641
Release: 2013-01-21
Genre: Medical
ISBN: 0521765900

Metabolomics, the global characterisation of the small molecule complement involved in metabolism, has evolved into a powerful suite of approaches for understanding the global physiological and pathological processes occurring in biological organisms. The diversity of metabolites, the wide range of metabolic pathways and their divergent biological contexts require a range of methodological strategies and techniques. Methodologies for Metabolomics provides a comprehensive description of the newest methodological approaches in metabolomic research. The most important technologies used to identify and quantify metabolites, including nuclear magnetic resonance and mass spectrometry, are highlighted. The integration of these techniques with classical biological methods is also addressed. Furthermore, the book presents statistical and chemometric methods for evaluation of the resultant data. The broad spectrum of topics includes a vast variety of organisms, samples and diseases, ranging from in vivo metabolomics in humans and animals to in vitro analysis of tissue samples, cultured cells and biofluids.

Handbook of Bioanalytics

Handbook of Bioanalytics
Author: Bogusław Buszewski
Publisher: Springer Nature
Total Pages: 1091
Release: 2022-06-30
Genre: Science
ISBN: 3030956601

This book presents an authoritative review of analytical methods used for diagnostics, medical therapy and for forensic purposes. Divided into 4 parts, the book discusses new challenges in bioanalytics, covers bioanalysis as a source of clinical, pharmaceutical and forensic information, explores natural resources as a source of biologically active compounds, and offers new analytical strategies and equipment solutions. Written by interdisciplinary expert academics, this work will appeal to a wide readership of students, researchers and professionals interested in the fields of medicine, chemistry, pharmaceutical, life and health sciences, engineering and environmental protection. Clinicians and employees of forensic laboratories will also find this work instructive and informative.

Principles of Translational Science in Medicine

Principles of Translational Science in Medicine
Author: Martin Wehling
Publisher: Academic Press
Total Pages: 495
Release: 2021-07-15
Genre: Science
ISBN: 032399962X

Principles of Translational Science in Medicine: From Bench to Bedside, Third Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing number of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. New chapters include: Translation in Oncology, Biologicals, and Orphan Drugs. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine and is written by worldwide experts in their respective fields. - Includes state-of-the-art principles, tools such as biomarkers and early clinical trials, algorithms of translational science in medicine - Provides in-depth description of special translational aspects in the currently most successful areas of clinical translation, namely oncology and immunology - Covers status of institutionalization of translational medicine, networking structures and outcomes at the level of marketing authorization

Bioremediation for Environmental Pollutants

Bioremediation for Environmental Pollutants
Author: Inamuddin
Publisher: Bentham Science Publishers
Total Pages: 395
Release: 2023-06-23
Genre: Science
ISBN: 981512353X

Increased industrial and agricultural activity has led to the contamination of the earth's soil and groundwater resources with hazardous chemicals. The presence of heavy metals, dyes, fluorides, dissolved solids, and many other pollutants used in industry and agriculture are responsible for hazardous levels of water pollution. The removal of these pollutants in water resources is challenging. Bioremediation is a new technique that employs living organisms, usually bacteria and fungi, to remove pollutants from soil and water, preferably in situ. This approach is more cost-effective than traditional techniques, such as incineration of soils and carbon filtration of water. It requires understanding how organisms consume and transform polluting chemicals, survive in polluted environments, and how they should be employed in the field. Bioremediation for Environmental Pollutants discusses the latest research in green chemistry and practices and principles involved in quality improvement of water by remediation. It covers different aspects of environmental problems and their remedies with up-to-date developments in the field of bioremediation of industrial/environmental pollutants. Volume 2 explains the methods used to control the remediation processes making it cost-effectively and feasible. It elaborates on the application of microbial enzymes, microalgae, and genetically engineered microorganisms in the bioremediation of significant pollutants, food wastes, distillery wastewater, and pharmaceutical wastes. This book is invaluable for researchers and scientists in environmental science, environmental microbiology, and waste management. It also serves as a learning resource for graduate and undergraduate students in environmental science, microbiology, limnology, freshwater ecology, and microbial biotechnology.

Multi-Pronged Omics Technologies to Understand COVID-19

Multi-Pronged Omics Technologies to Understand COVID-19
Author: Sanjeeva Srivastava
Publisher: CRC Press
Total Pages: 237
Release: 2022-07-07
Genre: Science
ISBN: 1000595609

"COVID-19 and Omics Technologies" is a comprehensive, integrative assessment of recent information and knowledge collected on SARS-CoV-2 and COVID-19 during the pandemic based on omics technologies. It demonstrates how omics technologies could better investigate the infectious disease and propose solutions to the current concerns. The value of multi-omics technologies in understanding disease etiology and host response, discovering infection biomarkers and illness prediction, identifying vaccine candidates, discovering therapeutic targets, and tracing pathogen evolution is discussed in this book. These factors combine to make it a valuable resource to enhance understanding of both "Omics technology" and "COVID-19" as a disease. The book covers the most recent understanding of COVID-19 and the applications of cutting-edge studies, making it accessible to a large multidisciplinary readership. The book explains how high-throughput technologies and systems biology might assist to solve the pandemic’s challenges and deconstruct and appreciate the substantial contributions that omics technologies have made in predicting the path of this unforeseeable pandemic. Features: In-depth summary of clinical presentation, epidemiological impact, and long-term sequelae of COVID-19 pandemic. A systematic overview of omics-based approaches to the study of COVID-19 biology. Recent research results and some pointers to future advancements in methodologies used. Detailed examples from recent studies on COVID-19 encompassing different omics methodologies. A detailed description of methodologies and notes on the applications of state-of-the-art technologies. This book is intended for scientists who need to understand the biology of COVID-19 from the perspective of omics investigations, as well as researchers who want to employ omics-based technologies in disease biology.