Mechanistic Bioinorganic Chemistry
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Author | : American Chemical Society. Meeting |
Publisher | : |
Total Pages | : 528 |
Release | : 1995 |
Genre | : Language Arts & Disciplines |
ISBN | : |
Provides an understanding of bioinorganic reactions from a mechanistic point of view. Illustrates how spectroscopy can be used to establish mechanisms and how model compounds provide mechanistic insight for enzymes. Demonstrates how to apply numerous physical methods to understanding mechanisms of redox catalysis by metal centers in enzymes. Highlights the interrelationships between the roles of metal ions in electron transfer, redox catalysis, structural roles, and hydrolytic chemistry. Provides mechanistic insights into water oxidation, nitrogen fixation, nucleic acid oxidation and hydrolysis, oxygen binding, catalase reactions, and electron transfer.
Author | : George Chia-Chen Yeh |
Publisher | : |
Total Pages | : 488 |
Release | : 1997 |
Genre | : |
ISBN | : |
Author | : Ivano Bertini |
Publisher | : University Science Books |
Total Pages | : 794 |
Release | : 2007 |
Genre | : Science |
ISBN | : 9781891389436 |
Part A.: Overviews of biological inorganic chemistry : 1. Bioinorganic chemistry and the biogeochemical cycles -- 2. Metal ions and proteins: binding, stability, and folding -- 3. Special cofactors and metal clusters -- 4. Transport and storage of metal ions in biology -- 5. Biominerals and biomineralization -- 6. Metals in medicine. -- Part B.: Metal ion containing biological systems : 1. Metal ion transport and storage -- 2. Hydrolytic chemistry -- 3. Electron transfer, respiration, and photosynthesis -- 4. Oxygen metabolism -- 5. Hydrogen, carbon, and sulfur metabolism -- 6. Metalloenzymes with radical intermediates -- 7. Metal ion receptors and signaling. -- Cell biology, biochemistry, and evolution: Tutorial I. -- Fundamentals of coordination chemistry: Tutorial II.
Author | : Rosette M. Roat-Malone |
Publisher | : John Wiley & Sons |
Total Pages | : 544 |
Release | : 2007-10-05 |
Genre | : Science |
ISBN | : 0471761133 |
An updated, practical guide to bioinorganic chemistry Bioinorganic Chemistry: A Short Course, Second Edition provides the fundamentals of inorganic chemistry and biochemistry relevant to understanding bioinorganic topics. Rather than striving to provide a broad overview of the whole, rapidly expanding field, this resource provides essential background material, followed by detailed information on selected topics. The goal is to give readers the background, tools, and skills to research and study bioinorganic topics of special interest to them. This extensively updated premier reference and text: Presents review chapters on the essentials of inorganic chemistry and biochemistry Includes up-to-date information on instrumental and analytical techniques and computer-aided modeling and visualization programs Familiarizes readers with the primary literature sources and online resources Includes detailed coverage of Group 1 and 2 metal ions, concentrating on biological molecules that feature sodium, potassium, magnesium, and calcium ions Describes proteins and enzymes with iron-containing porphyrin ligand systems-myoglobin, hemoglobin, and the ubiquitous cytochrome metalloenzymes-and the non-heme, iron-containing proteins aconitase and methane monooxygenase Appropriate for one-semester bioinorganic chemistry courses for chemistry, biochemistry, and biology majors, this text is ideal for upper-level undergraduate and beginning graduate students. It is also a valuable reference for practitioners and researchers who need a general introduction to bioinorganic chemistry, as well as chemists who want an accessible desk reference.
Author | : Enzo Alessio |
Publisher | : John Wiley & Sons |
Total Pages | : 625 |
Release | : 2011-02-25 |
Genre | : Science |
ISBN | : 352763312X |
This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic.
Author | : Stephen J. Lippard |
Publisher | : University Science Books |
Total Pages | : 444 |
Release | : 1994 |
Genre | : Medical |
ISBN | : 9780935702729 |
The use of unnatural metals - which have been introduced into human biology as diagnostic probes and drugs - is another active area of tremendous medical significance.
Author | : Robert R. Crichton |
Publisher | : Elsevier |
Total Pages | : 504 |
Release | : 2019-09-10 |
Genre | : Science |
ISBN | : 0444642269 |
Practical Approaches to Biological Inorganic Chemistry, Second Edition, reviews the use of spectroscopic and related analytical techniques to investigate the complex structures and mechanisms of biological inorganic systems that contain metals. Each chapter presents an overview of the technique, including relevant theory, a clear explanation of what it is, how it works, and how the technique is actually used to evaluate biological structures. New chapters cover Raman Spectroscopy and Molecular Magnetochemistry, but all chapters have been updated to reflect the latest developments in discussed techniques. Practical examples, problems and many color figures are also included to illustrate key concepts. The book is designed for researchers and students who want to learn both the basics and more advanced aspects of key methods in biological inorganic chemistry. Presents new chapters on Raman Spectroscopy and Molecular Magnetochemistry, as well as updated figures and content throughout Includes color images throughout to enable easier visualization of molecular mechanisms and structures Provides worked examples and problems to help illustrate and test the reader’s understanding of each technique Written by leading experts who use and teach the most important techniques used today to analyze complex biological structures
Author | : Ajay Kumar Goswami |
Publisher | : Walter de Gruyter GmbH & Co KG |
Total Pages | : 148 |
Release | : 2022-01-19 |
Genre | : Science |
ISBN | : 1501516116 |
The book provides a detailed state-of-the-art overview of inorganic chemistry applied to medicinal chemistry and biology. It covers the newly emerging field of metals in medicine and the future of medicinal inorganic chemistry. It is an essential reading for every researcher and student in medicinal and bioinorganic chemistry.
Author | : Ei-Ichiro Ochiai |
Publisher | : Academic Press |
Total Pages | : 373 |
Release | : 2010-07-20 |
Genre | : Science |
ISBN | : 0080886973 |
Written by a preeminent teacher and scientist in the field, Bioinorganic Chemistry provides specialists, students, and general readers with an understanding of the basic chemistry of interactions of inorganic substances with biological systems at the molecular level. The author presents bioinorganic concepts in context and brings a distinct chemistry perspective to the subject. Provides the streamlined coverage appropriate for one-semester courses or independent study, with all of the necessary but none of the excessive information Prepares readers to move to the next level of study (whether they continue on in the field or transition to medicine/industry) Presents concepts through extensive four-color visuals, appealing to a range of learning styles Promotes critical thinking through open-ended questions throughout the narrative and at the end of each chapter
Author | : Markus W. Ribbe |
Publisher | : Springer Nature |
Total Pages | : 169 |
Release | : 2019-09-11 |
Genre | : Science |
ISBN | : 3030258971 |
This volume highlights recent progress on the fundamental chemistry and mechanistic understanding of metallocofactors, with an emphasis on the major development in these areas from the perspective of bioinorganic chemistry. Metallocofactors are essential for all forms of life and include a variety of metals, such as iron, molybdenum, vanadium, and nickel. Structurally fascinating metallocofactors featuring these metals are present in many bacteria and mediate remarkable metabolic redox chemistry with small molecule substrates, including N2, CO, H2, and CO2. Current interest in understanding how these metallocofactors function at the atomic level is enormous, especially in the context of sustainably feeding and fueling our planet; if we can understand how these cofactors work, then there is the possibility to design synthetic catalysts that function similarly.