Mechanics Of The Mitral Valve An In Vivo In Silico Approach
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| Author | : Michel R. Labrosse |
| Publisher | : CRC Press |
| Total Pages | : 386 |
| Release | : 2018-09-13 |
| Genre | : Medical |
| ISBN | : 1315280280 |
The objective of this book is to illustrate in specific detail how cardiovascular mechanics stands as a common pillar supporting such different clinical successes as drugs for high blood pressure, prosthetic heart valves and coronary artery bypass grafting, among others. This information is conveyed through a comprehensive treatment of the overarching principles and theories that are behind mechanobiological processes, aortic and arterial mechanics, atherosclerosis, blood and microcirculation, hear valve mechanics, as well as medical devices and drugs. Examines all major theoretical and practical aspects of mechanical forces related to the cardiovascular system. Discusses a unique coverage of mechanical changes related to an aging cardiovascular system. Provides an overview of experimental methods in cardiovascular mechanics. Written by world-class researchers from Canada, the US and EU. Extensive references are provided at the end of each chapter to enhance further study. Michel R. Labrosse is the founder of the Cardiovascular Mechanics Laboratory at the University of Ottawa, where he is a full professor within the Department of Mechanical Engineering. He has been an active researcher in academia along with being heavily associated with the University of Ottawa Heart Institute. He has authored or co-authored over 90 refereed communications, and supervised or co-supervised over 40 graduate students and post-docs.
| Author | : Hikaru Matsuda |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 153 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 4431679170 |
Rotary blood pumps increasingly are being used in open heart surgery and in assisted circulation for patients with heart disease. These rotary devices include vortex (centrifugal) and axial pumps, which can be utilized in conditions where the use of conventional pulsatile pumps would entail problems of cost and size. Rapid progress is now being made in developing new devices for controlling blood flow within the heart and great vessels as well as extracorporeally for use in coronary and intensive care units and, in the future, for long-term use. This book provides information on the physiology of nonpulsatile circulation, the development of rotary pump engineering, and the clinical application of rotary blood pumps. It also presents an overview of future developments in this important field.
| Author | : Michael S. Sacks |
| Publisher | : Springer |
| Total Pages | : 500 |
| Release | : 2019-04-08 |
| Genre | : Science |
| ISBN | : 3030019934 |
This book covers the latest research development in heart valve biomechanics and bioengineering, with an emphasis on novel experimentation, computational simulation, and applications in heart valve bioengineering. The most current research accomplishments are covered in detail, including novel concepts in valvular viscoelasticity, fibril/molecular mechanisms of tissue behavior, fibril kinematics-based constitutive models, mechano-interaction of valvular interstitial and endothelial cells, biomechanical behavior of acellular valves and tissue engineered valves, novel bioreactor designs, biomechanics of transcatheter valves, and 3D heart valve printing. This is an ideal book for biomedical engineers, biomechanics, surgeons, clinicians, business managers in the biomedical industry, graduate and undergraduate students studying biomedical engineering, and medical students.
| Author | : Julius Guccione |
| Publisher | : Frontiers Media SA |
| Total Pages | : 289 |
| Release | : 2020-01-13 |
| Genre | : |
| ISBN | : 2889633233 |
| Author | : Gerhard Sommer |
| Publisher | : Springer Nature |
| Total Pages | : 447 |
| Release | : 2022-06-14 |
| Genre | : Technology & Engineering |
| ISBN | : 3030923398 |
This book offers a comprehensive and timely overview of the latest developments in the field of biomechanics and extensive knowledge of tissue structure, function, and modeling. Gathering chapters written by authoritative scientists, it reports on a range of continuum and computational models of solids, and related experimental works, for biomechanical applications. It discusses cutting-edge advances such as constitutive modeling and computational simulation of biological tissues and organs under physiological and pathological conditions, and their mechanical characterization. It covers innovative studies on arteries, heart, valvular tissue, and thrombus, brain tumor, muscle, liver, kidney, and stomach, among others. Written in honor of Professor Gerhard A. Holzapfel, the book provides specialized readers with a thorough and timely overview of different types of modeling in biomechanics, and current knowledge about biological structures and function.
| Author | : David Rubenstein |
| Publisher | : Academic Press |
| Total Pages | : 544 |
| Release | : 2015-07-28 |
| Genre | : Technology & Engineering |
| ISBN | : 0128011696 |
Biofluid Mechanics: An Introduction to Fluid Mechanics, Macrocirculation, and Microcirculation shows how fluid mechanics principles can be applied not only to blood circulation, but also to air flow through the lungs, joint lubrication, intraocular fluid movement, renal transport among other specialty circulations. This new second edition increases the breadth and depth of the original by expanding chapters to cover additional biofluid mechanics principles, disease criteria, and medical management of disease, with supporting discussions of the relevance and importance of current research. Calculations related both to the disease and the material covered in the chapter are also now provided. - Uses language and math that is appropriate and conducive for undergraduate learning, containing many worked examples and end-of-chapter problems - Develops all engineering concepts and equations within a biological context - Covers topics in the traditional biofluids curriculum, and addresses other systems in the body that can be described by biofluid mechanics principles - Discusses clinical applications throughout the book, providing practical applications for the concepts discussed - NEW: Additional worked examples with a stronger connection to relevant disease conditions and experimental techniques - NEW: Improved pedagogy, with more end-of-chapter problems, images, tables, and headings, to better facilitate learning and comprehension of the material
| Author | : Shaun D. Gregory |
| Publisher | : Elsevier |
| Total Pages | : 1374 |
| Release | : 2024-11-02 |
| Genre | : Science |
| ISBN | : 0443221472 |
Mechanical Circulatory and Respiratory Support, Second Edition, continues to provide a comprehensive overview of the past, present and future development of mechanical circulatory and respiratory support devices. This new edition provides an update on the field while also introducing new elements within the field such as ex-vivo perfusion, devices for HFpEF, design for manufacture, oxygenator design, and more content on route to market. Chapters from over 60 internationally-renowned experts focuses on the entire life-cycle of mechanical circulatory and respiratory support – from the descent into heart and lung failure, alternative medical management, device options, device design, implantation techniques, complications and medical management of the supported patient, patient-device interactions, cost effectiveness, route to market and a view to the future. This second edition is a useful resource for biomedical engineers and clinicians who are designing new mechanical circulatory or respiratory support devices, while also providing a comprehensive guide of the entire field for those who are already familiar with some areas and want to learn more. Reviews of the most cutting-edge research are provided throughout each chapter, along with guides on how to design new devices and which areas require specific focus for future research and development. - Presents an engineering pathway to develop the most advanced medical devices - Features a clinical summary of how to select the right patients and treat them optimally while supported with these devices - Includes a detailed path to market for those developing new devices in this field
| Author | : Pollnow, Stefan |
| Publisher | : KIT Scientific Publishing |
| Total Pages | : 296 |
| Release | : 2019-04-23 |
| Genre | : Technology (General) |
| ISBN | : 3731508869 |
Catheter ablation is a major treatment for atrial tachycardias. Hereby, the precise monitoring of the lesion formation is an important success factor. This book presents computational, wet-lab, and clinical studies with the aim of evaluating the signal characteristics of the intracardiac electrograms (IEGMs) recorded around ablation lesions from different perspectives. The detailed analysis of the IEGMs can optimize the description of durable and complex lesions during the ablation procedure.
| Author | : Ewa Pietka |
| Publisher | : Springer Nature |
| Total Pages | : 370 |
| Release | : 2020-09-02 |
| Genre | : Technology & Engineering |
| ISBN | : 303049666X |
The rapid and continuous growth in the amount of available medical information and the variety of multimodal content has created demand for a fast and reliable technology capable of processing data and delivering results in a user-friendly manner, whenever and wherever the information is needed. Multimodal acquisition systems, AI-powered applications, and biocybernetic support for medical procedures, physiotherapy and prevention have opened up exciting new avenues in terms of optimizing the healthcare system for the benefit of patients. This book presents a comprehensive study on the latest advances in medical data science and gathers carefully selected articles written by respected experts on information technology. Pursuing an interdisciplinary approach and addressing both theoretical and applied aspects, it chiefly focuses on: Artificial Intelligence Image Analysis Sound and Motion in Physiotherapy and Physioprevention Modeling and Simulation Medical Data Analysis Given its scope, the book offers a valuable reference tool for all scientists who deal with problems of designing and implementing information processing tools employed in systems that assist in patient diagnosis and treatment, as well as students who want to learn more about the latest innovations in quantitative medical data analysis, data mining, and artificial intelligence.
| Author | : Udi Nussinovitch |
| Publisher | : Academic Press |
| Total Pages | : 556 |
| Release | : 2020-08-19 |
| Genre | : Medical |
| ISBN | : 012813707X |
The increasing pace of advances in cardiology throughout the last few decades has fundamentally altered the natural course of heart patients. In the last few years, available therapies have been revolutionized completely by new transcatheter therapeutic approaches, novel ventricular assist devices, and new drugs. Also, molecular biology and genetics have a rapidly growing impact on cardiovascular diseases, enabling the field of regenerative medicine to become increasingly closer to routine clinical implementation. Emerging Technologies for Heart Diseases was conceived to cover the recent extensive literature on current and novel therapeutic options for cardiac patients. The first volume is dedicated to heart failure and valvular disorders, and the second covers myocardial ischemia and arrhythmias. The clinical topic is addressed in several chapters divided according to the therapeutic approach (mechanical or electrical device-based, or cell and gene-based). Each of the 46 chapters focuses on clinically available solutions, new therapies currently under evaluation in clinical trials, promising preclinical technologies, and emerging concepts and innovations that have not yet been tested in a preclinical model. Also, the book discusses future challenges and opportunities for clinical implementation. Lessons learned from abandoned experimental practices are also covered, giving the readers the widest possible perspective of current therapeutic dilemmas. Overall, this textbook was designed for physicians who want to stay up-to-date with current therapies and those of the future, for biomedical companies, and for those who wish to broaden their knowledge of new cardiovascular therapeutic options. - Provides a comprehensive review of the latest therapeutic developments for heart failure, valvular disorders, myocardial ischemia and arrhythmias, and their clinical implications - Written by both specialists in the field and established researchers, it delivers a review of emerging medical technologies and presents insight into their therapeutic promise - Chapters are arranged according to disease pathogeneses and relevance and include coverage of the mechanical, electrophysiological, and biological approaches for the management of patients with heart failure should be replaced with heart failure and valvular disorders
