Pediatric Brain Stimulation

Pediatric Brain Stimulation
Author: Adam Kirton
Publisher: Academic Press
Total Pages: 504
Release: 2016-05-04
Genre: Medical
ISBN: 0128020385

Pediatric Brain Stimulation: Mapping and Modulating the Developing Brain presents the latest on this rapidly expanding field that has seen an exponential growth in publications over the past 10 years. Non-invasive modalities like TMS can painlessly map and measure complex neurophysiology in real patients. Neuromodulatory applications like rTMS and tDCS carry increasingly proven therapeutic applications. Rapidly advancing technological methodologies are increasing opportunities and indications. Despite all these benefits, applications in the more plastic developing brains of children are only just emerging. This book provides a comprehensive overview of brain stimulation in children. Chapters include Transcranial Magnetic Stimulation (TMS) fundamentals, brain stimulation in pediatric neurological conditions, and invasive brain stimulation. The main audience for this research will be those interested in applying brain stimulation technologies to advance clinical research and patient care, although a wide variety of clinicians and scientist will find this to be a valuable reference on brain stimulation with specific chapters on a variety of conditions. Provides an overview of recent findings and knowledge of pediatric brain stimulation and the developing brain Edited by renowned leaders in the field of pediatric brain stimulation Presents a great resource for basic and clinical scientists and practitioners in neuroscience, neurology, neurosurgery, and psychiatry

Non-Invasive Neuromodulation of the Central Nervous System

Non-Invasive Neuromodulation of the Central Nervous System
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Total Pages: 103
Release: 2015-11-02
Genre: Medical
ISBN: 0309376211

Based on advances in biotechnology and neuroscience, non-invasive neuromodulation devices are poised to gain clinical importance in the coming years and to be of increasing interest to patients, clinicians,health systems, payers, and industry. Evidence suggests that both therapeutic and non-therapeutic applications of non-invasive neuromodulation will continue to expand in coming years, particularly for indications where treatments are currently insufficient, such as drug-resistant depression. Given the growing interest in non-invasive neuromodulation technologies, the Institute of Medicine's Forum on Neuroscience and Nervous System Disorders convened a workshop, inviting a range of stakeholders - including developers of devices and new technologies, researchers, clinicians, ethicists, regulators, and payers - to explore the opportunities, challenges, and ethical questions surrounding the development, regulation, and reimbursement of these devices for the treatment of nervous system disorders as well as for non-therapeutic uses, including cognitive and functional enhancement. This report highlights the presentation and discussion of the workshop.

The Stimulated Brain

The Stimulated Brain
Author: Roi Cohen Kadosh
Publisher: Elsevier
Total Pages: 568
Release: 2014-06-01
Genre: Medical
ISBN: 0124047122

The Stimulated Brain—which garnered an Honorable Mention for Biomedicine & Neuroscience at the 2015 PROSE Awards from the Association of American Publishers—presents the first integration of findings on brain stimulation from different research fields with a primary focus on Transcranial Electrical Stimulation (tES), one of the most frequently used noninvasive stimulation methods. The last decade has witnessed a significant increase in the amount of research exploring how noninvasive brain stimulation can not only modulate but also enhance cognition and brain functions. However, although Transcranial Magnetic Stimulation (TMS) and particularly tES have the potential to become more widely applicable techniques (as they come with none of the risks associated with deep brain stimulation) the reference literature on these neurotechnologies has been sparse. This resource provides a broad survey of current knowledge, and also marks future directions in cognitive and neuro-enhancement. It expands our understanding of basic research findings from animals and humans, including clear translational benefits for applied research and the therapeutic use of noninvasive brain stimulation methods. The book's coverage includes a primer that paves the way to a more advanced knowledge of tES and its physiological basis; current research findings on cognitive and neuro-enhancement in animals and typical and atypical human populations, such as neurological patients; and discussions of future directions, including specific neuroethical issues and pathways for collaboration and entrepreneurialism. The Stimulated Brain is the first book to provide a comprehensive understanding of different aspects of noninvasive brain stimulation that are critical for scientists, clinicians, and those who are interested in “stimulating their minds by exploring this fascinating field of research. Honorable Mention for Biomedicine & Neuroscience in the 2015 PROSE Awards from the Association of American Publishers The only reference on the market to focus on transcranial electrical stimulation (tES) Coverage across technical, historical, and application topics makes this the single, comprehensive resource for researchers and students Edited book with chapters authored by international leaders in the fields of medicine, neuroscience, psychology, and philosophy—providing the broadest, most expert coverage available

The Safety and Efficacy of Noninvasive Brain Stimulation in Development and Neurodevelopmental Disorders

The Safety and Efficacy of Noninvasive Brain Stimulation in Development and Neurodevelopmental Disorders
Author: Lindsay M. Oberman
Publisher: Frontiers Media SA
Total Pages: 70
Release: 2015-12-03
Genre: Neurosciences. Biological psychiatry. Neuropsychiatry
ISBN: 2889196992

Noninvasive brain stimulation (including Transcranial Magnetic Stimulation (TMS) and Transcranial Current Brain Stimulation (TCS)) can be used both experimentally and therapeutically. In the experimental domain TMS can be applied in single pulses to depolarize a small population of neurons in a targeted brain region. This protocol can be used, for example, to map cortical motor outputs, study central motor conduction time, or evaluate the cortical silent period (a measure of intracortical inhibition) all of which are relevant to neurodevelopment. TMS can also be applied in pairs of pulses (paired pulse stimulation, ppTMS) where two pulses are presented in rapid succession to study intracortical inhibition and facilitation. Trains of repeated TMS (rTMS) pulses can be applied at various stimulation frequencies and patterns to modulate local cortical excitability beyond the duration of the stimulation itself. Depending on the parameters of stimulation the excitability can be either facilitated or suppressed. TCS (including Transcranial Direct Current Stimulation (tDCS), alternating current (tACS), and random noise current stimulation (tRNS) also have the potential to modulate cortical excitability and have also been used to study and modulate cortical activity in healthy and patient populations. The after-effects of rTMS and TCS are thought to be related to changes in efficacy (in either the positive or negative direction) of synaptic connections of the neurons being stimulated, thus these techniques have been used to study and modulate cortical plasticity mechanisms in a number of populations. Recently, researchers have begun to apply these techniques to the study of neurodevelopmental mechanisms as well as the pathophysiology and development of novel treatments for neurodevelopmental disorders. Though there is much promise, caution is warranted given the vulnerability of pediatric and clinical populations and the potential that these techniques have to modify circuit development in a cortex that is in a very dynamic state. This Research Topic hopes to provide an opportunity to share ideas across areas (human and animal researchers, clinicians and basic scientists). We are particularly interested in papers that address issues of choosing a protocol (intensity, frequency, location, coil geometry etc.), populations where noninvasive brain stimulation may have direct impact on diagnostics and treatment, as well as the safety and ethics of applying these techniques in pediatric populations. As many may not be aware of the potential and limitations of noninvasive brain stimulation and its use for research and treatment in this area, this Research Topic promises to have broad appeal. Submissions for all Frontiers article types are encouraged.

Non-Invasive Brain Stimulation

Non-Invasive Brain Stimulation
Author: Carlo Miniussi
Publisher: Psychology Press
Total Pages: 218
Release: 2011
Genre: Medical
ISBN: 1848727569

This book includes state-of-the art reviews, written by research leaders, of Non-Invasive Brain-Stimulation (NIBS) techniques for the cognitive rehabilitation of disorders of memory, language, perception, attention and executive functions.

Non Invasive Brain Stimulation in Psychiatry and Clinical Neurosciences

Non Invasive Brain Stimulation in Psychiatry and Clinical Neurosciences
Author: Bernardo Dell'Osso
Publisher: Springer Nature
Total Pages: 365
Release: 2020-07-31
Genre: Medical
ISBN: 3030433560

This book presents the state of the art regarding the use of non-invasive brain stimulation (TMS and tDCS) in the research and treatment of neuropsychiatric disorders. The contributions, all of which were prepared by internationally recognized experts in the field, are divided into two main sections (for TMS and tDCS, respectively) across diagnoses, following an introductory section on the mechanisms of action and neurophysiological background. Neuropsychological perspectives and approaches are provided as well. The book is ultimately intended to offer a unique, integrated approach to the use of non-invasive brain stimulation across the clinical neurosciences, providing a comprehensive and updated perspective that will benefit psychiatrists, neurologists, clinical psychologists and neurophysiologists alike.

Brain Stimulation and Behavioral Change

Brain Stimulation and Behavioral Change
Author: Claudio Lucchiari
Publisher: Frontiers Media SA
Total Pages: 183
Release: 2019-05-15
Genre:
ISBN: 2889458385

The eBook entitled “Brain Stimulation and Behavioral Change” is a collection of articles about the use of transcranial electric stimulation (tES) to change behaviors and face pathological conditions, to enhance cognition and to explore cerebral functions using safe and non-invasive brain modulation techniques. The tESs include transcranial direct current stimulation (tDCS), transcranial alternate current stimulation (tACS), and, due to the way it induces changes in the brain, Transcranial Magnetic Stimulation (TMS). The use of tES has recently exploded. Certainly, one reason for this explosion of research is that it is a cheap way to change behavior. However, on the other hand, we still know very little about the neural mechanisms that underlie tES. The present eBook includes both original studies and reviews. It covers a wide scope of arguments, including studies aimed at testing the potential ability of tES in mitigating physical and psychiatric symptoms, and to support neurological rehabilitation, enhancing reading abilities, motor abilities, and creativity. Furthermore, some contributions about the role of tES in discovering and mapping the neuro-functional correlates of higher cognitive functions are also included. The common background of the contributions included in the eBook lies in the idea that we need sound scientific evidence about how to move these techniques from labs to real-life contexts. Addressing these issues and understanding the real potentialities of tES in clinical and non-clinical applications require a significant cross-fertilization between disciplines. We hope this eBook will be able to boost the discussion on this vital topic.