Measurement in Laboratory Medicine

Measurement in Laboratory Medicine
Author: Paul W. Strike
Publisher:
Total Pages: 280
Release: 1996
Genre: Medical
ISBN:

This text aims to serve as a guide to the practical aspects of the control and interpretation of laboratory test results. It covers test evaluation, interpretation and quality assurance and examines key questions.

Systematic Error Detection in Laboratory Medicine

Systematic Error Detection in Laboratory Medicine
Author: Amir Momeni-Boroujeni
Publisher:
Total Pages:
Release: 2018
Genre: Economics
ISBN:

Measurements in laboratory medicine have a degree of uncertainty; this uncertainty is often called "error" and refers to imprecisions and inaccuracies in measurement. This measurement error refers to the difference between the true value of the measured sample and the measured value. One of the types of error is systematic error, also called bias, because these errors errors are reproducible and skew the results consistently in the same direction. A common approach to identify systematic error is to use control samples with a method comparison approach. An alternative is use of statistical methods that analyze actual patient values either as an "Average of Normals" or a "Moving Patient Averages." Fundamental questions should be decided before a quality control method is used: how are weights assigned to the results? Is preference given to more recent samples or to the older samples? How sensitive should the model be? In this chapter, we will expand the fundamental notion of systematic error and explain why it is difficult to identify and measure and current statistical methods that are used to detect systematic error or bias.

Clinical Laboratory Medicine

Clinical Laboratory Medicine
Author: Kenneth D. McClatchey
Publisher: Lippincott Williams & Wilkins
Total Pages: 1732
Release: 2002
Genre: Medical
ISBN: 9780683307511

This thoroughly updated Second Edition of Clinical Laboratory Medicine provides the most complete, current, and clinically oriented information in the field. The text features over 70 chapters--seven new to this edition, including medical laboratory ethics, point-of-care testing, bone marrow transplantation, and specimen testing--providing comprehensive coverage of contemporary laboratory medicine. Sections on molecular diagnostics, cytogenetics, and laboratory management plus the emphasis on interpretation and clinical significance of laboratory tests (why a test or series of tests is being done and what the results mean for the patient) make this a valuable resource for practicing pathologists, residents, fellows, and laboratorians. Includes over 800 illustrations, 353 in full color and 270 new to this edition. Includes a Self-Assessment and Review book.

Analytical Measurement Terminology

Analytical Measurement Terminology
Author: Elizabeth Prichard
Publisher: Royal Society of Chemistry
Total Pages: 88
Release: 2007-10-31
Genre: Science
ISBN: 184755928X

The variety of complex terms used in the Quality Assurance aspect of analytical measurement can be the cause of considerable confusion. This unique handbook explains the most widely-used terminology in language that is readily understood, and attempts to place each term in context. Concepts are described in a way that is useful to all practitioners, particularly those concerned with quality assurance, validation and reliability of analytical measurements. Explanations of terms are always in line with the "official definition", often developed by international committees. Adopting a thematic approach, Analytical Measurement Terminology is divided into six main parts. The first four parts address the logical progression of an analytical measurement, from obtaining a sample, through method and materials, to reporting the result. The two remaining parts include a variety of terms encountered in quality systems and documentation, along with definitions of "mathematical" terms likely to be encountered by the analyst in their everyday work. The index provides easy access to both the definitions and the accompanying examples. With its straightforward descriptions and many examples, this handbook, produced as part of the VAM (Valid Analytical Measurement) programme, will provide valuable assistance for a wide variety of new and experienced practitioners, as well as for teachers and lecturers.

Risk, Error and Uncertainty: Laboratory Quality Management in the Age of Metrology, An Issue of the Clinics in Laboratory Medicine, E-Book

Risk, Error and Uncertainty: Laboratory Quality Management in the Age of Metrology, An Issue of the Clinics in Laboratory Medicine, E-Book
Author: James O. Westgard
Publisher: Elsevier Health Sciences
Total Pages: 314
Release: 2017-02-06
Genre: Medical
ISBN: 032347764X

This issue of Clinics in Laboratory Medicine entitled “Risk, Error and Uncertainty: Laboratory Quality Management in the Age of Metrology will be guest edited by Sten Westgard, James Westgard, and David Armbruster. The issue will cover a broad range of topics related to management in the laboratory including but not limited to: Metrology Perspectives; Biologic Variation Approach to Daily Laboratory; Clinical Outcome Approach to Goal Setting; Six Sigma Quality Management System; Traceability and Comparability; MU, Risk, and Sigma-metrics at Sunway; and Quality Indicators for the Total Testing Process, among others.

Traceability in Chemical Measurement

Traceability in Chemical Measurement
Author: Paul De Bièvre
Publisher: Springer Science & Business Media
Total Pages: 318
Release: 2005-01-12
Genre: Science
ISBN: 9783540439899

Metrological traceability of chemical measurement results means the establishment of a relation to metrological stated references through an unbroken chain of comparisons. This volume collects 56 outstanding papers on the topic, mostly published in the period 2000-2003 in the journal "Accreditation and Quality Assurance". They provide the latest understanding, and possibly the rationalenbsp;why it is important to integrate the concept of metrological traceability including suitable measurement standards such as certified reference materials, into the standard measurement procedures of every analytical laboratory. In addition, this anthology considers the benefits to both the analytical laboratory and the user of the measurement results.

Statistical Bases of Reference Values in Laboratory Medicine

Statistical Bases of Reference Values in Laboratory Medicine
Author: Eugene K. Harris
Publisher: CRC Press
Total Pages: 388
Release: 1995-07-07
Genre: Mathematics
ISBN: 9780824793395

Examining the strengths and limitations of various standards of accuracy in clinical laboratory analyses, this detailed reference presents an in-depth study of important theoretical and empirical issues concerning the description, collection, and application of reference values in laboratory medicine.

Statistical Methods in Laboratory Medicine

Statistical Methods in Laboratory Medicine
Author: P. W. Strike
Publisher: Butterworth-Heinemann
Total Pages: 553
Release: 2014-05-16
Genre: Medical
ISBN: 1483161927

Statistical Methods in Laboratory Medicine focuses on the application of statistics in laboratory medicine. The book first ponders on quantitative and random variables, exploratory data analysis (EDA), probability, and probability distributions. Discussions focus on negative binomial distribution, non-random distributions, binomial distribution, fitting the binomial model to sample data, conditional probability and statistical independence, rules of probability, and Bayes' theorem. The text then examines inference, regression, and measurement and control. Topics cover analytical goals for assay precision, estimating the error variance components, indirect structural assays, functional assays, bivariate regression model, and least-squares estimates of the functional relation parameters. The manuscript takes a look at assay method comparison studies, multivariate analysis, forecasting and control, and test interpretation. Concerns include time series structure and terminology, polynomial regression, assessing the performance of the classification rule, quantitative screening tests, sample correlation coefficient, and computer assisted diagnosis. The book is a dependable reference for medical experts and statisticians interested in the employment of statistics in laboratory medicine.

Compendium of Terminology and Nomenclature of Properties in Clinical Laboratory Sciences

Compendium of Terminology and Nomenclature of Properties in Clinical Laboratory Sciences
Author: Georges Férard
Publisher: Royal Society of Chemistry
Total Pages: 212
Release: 2016-11-18
Genre: Medical
ISBN: 1782621075

There has been significant expansion and development in clinical laboratory sciences and, in particular, metrological concepts, definitions and terms since the previous edition of this book was published in 1995. It is of prime importance to standardize laboratory reports for reliable exchange of patient examination data without loss of meaning or accuracy. New disciplines have appeared and the interrelationships between different disciplines within clinical laboratory sciences demand a common structure and language for data exchange, in the laboratory and with the clinicians, necessitating additional coverage in this book. These new sections will be based upon recommendations published by various national, regional, and international bodies especially IUPAC and IFCC. This book groups and updates the recommendations and will be appropriate for laboratory scientists, medical professionals and students in this area.