Policymakers, practitioners, and educators frequently group Latina/o immigrant adolescents within a single homogenous category, thus creating a problem in understanding their diverse experiences. To explore these diverse Latina/o adolescent experiences this dissertation cross-culturally compares patterns of ethnic identity and acculturation across a group of Indigenous (Yucatec Maya) immigrant Latino/a adolescents in the U.S. with Yucatec Maya adolescents residing in Mexico and with non-Indigenous immigrant Latina/o adolescents in the U.S. How do ethnic identity, acculturation levels, perceived discrimination, and sense of school belonging compare across Yucatec Maya adolescents in the U.S., non-Yucatec Maya Latina/o adolescents in the U.S., and Yucatec Maya adolescents still in Mexico? What roles do individual factors such as gender, language, generation level, and external factors such as family, cultural practices, ethnic community networks, and peer relationships take in the adolescents' lives in the U.S. and in Yucatan? The study draws on ethnic identity and acculturation frameworks as they relate to perceived discrimination (the study of how the person targeted by discrimination reacts and interprets these acts) and to the adolescents' feelings of belonging at school. The participants included 65 Latina/o non-Yucatec Maya heritage adolescents living in the Los Angeles, California area, 66 Mexican Maya heritage immigrant adolescents living in San Francisco, California or the Los Angeles, California area, and 70 Mexican Maya heritage adolescents living in Yucatan, Mexico. All 201 adolescents took a survey incorporating measures of ethnic identity, acculturation, perceived discrimination, and school belonging. Thirty-eight of the adolescents participated in semi-structured interviews that explored attitudes toward school, culture, discrimination, family, community, and peers influencing the adolescents. Quantitative findings expose the intra-group differences across Yucatec Maya and non-Yucatec Maya Latina/os adolescents and the discrimination faced by the growing population of Yucatec Maya adolescents within the Latino/a immigrant groups. Language, gender, and generation all play roles in the amount of peer and adult perceived discrimination experienced and the distress caused by perceived discrimination across Indigenous and non-Indigenous adolescents. The quantitative findings ultimately show that Indigenous adolescents have different psychological and cultural experiences when compared to non-Indigenous Latina/o adolescents. Being Yucatec Maya, first generation, male, and/or knowledgeable of Maya would put the adolescent at a higher risk of experiencing more perceived discrimination acts and distress. More perceived discrimination from adults also relates to adolescents in the U.S. (both Yucatec Maya and non-Yucatec Maya) resulting in lower levels of school belonging. The qualitative findings across the non-Yucatec Maya adolescents, Yucatec Maya adolescents in the U.S., and Yucatec Maya adolescents in Mexico reveal an in depth look at multiple perspectives surrounding cultural and ethnic identity, cultural practices, American culture, discrimination, school, family, and peers. Specifically for the Yucatec Maya adolescents, the interviews provided a lens into their sentiments about the Maya culture and preserving the culture for future generations. The interviews reflect the agency, reclamation of culture, and lived experiences that make up the Indigenous and non-Indigenous adolescents of this study. The study exposes the Yucatec Maya youth's resilient Indigenous identity that emerges regardless of the discrimination they face from non-Latina/o/non-Mexican groups as well as from their own Latina/o/Mexican communities. This understanding is needed to provide more comprehensive resources and services to these adolescents.