Maximising Recovery Of Function After Severe Spinal Cord Injury By Combining Electrical Epidural Stimulation Locomotor Training And Intraspinal Lentiviral Mediated Chondroitinase Abc Delivery
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Author | : Cristina Morganti-Kossmann |
Publisher | : Cambridge University Press |
Total Pages | : 361 |
Release | : 2012-07-19 |
Genre | : Medical |
ISBN | : 1107007437 |
Presents the most up-to-date clinical and experimental research in neurotrauma in an illustrated, accessible, comprehensive volume.
Author | : António Salgado |
Publisher | : Elsevier |
Total Pages | : 712 |
Release | : 2020-06-10 |
Genre | : Medical |
ISBN | : 0128180854 |
Handbook of Innovations in CNS Regenerative Medicine provides a comprehensive overview of the CNS regenerative medicine field. The book describes the basic biology and anatomy of the CNS and how injury and disease affect its balance and the limitations of the present therapies used in the clinics. It also introduces recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies. Finally, the book presents successful cases of translation of basic research to first-in-human trials and the steps needed to follow this path. Areas such as cell transplantation approaches, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies are key in regenerative medicine are covered in the book, along with regulatory and ethical issues. - Describes the basic biology and anatomy of the CNS and how injury and disease affect its balance - Discusses the limitations of present therapies used in the clinics - Introduces the recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies, and enabling technologies - Presents successful cases of translation of basic research to first-in-human trials, along with the steps needed to follow this path
Author | : Michael K. Danquah |
Publisher | : Springer Science & Business Media |
Total Pages | : 712 |
Release | : 2013-06-14 |
Genre | : Science |
ISBN | : 162703417X |
Examples from various organs and diseases illustrate the potential benefit obtained when both therapeutic approaches are combined with delivery strategies. Representing the combined effort of several leading international research and clinical experts, this book, Emerging Trends in Cell and Gene Therapy, provides a complete account on and brings into sharp focus current trends and state-of-the-art in important areas at the interface of cell- and gene-based therapies. This book addresses the current fragmented understanding regarding these two research areas and fills the vast unmet educational need and interest of both students and researchers in academia and industry. Main features of the book: · Biological aspects of stem cell sources, differentiation and engineering. · Application of microfluidics to study stem cell dynamics · Potential clinical application of stem cells and gene therapy to specific human disease. · Utilization of biomaterials and stem cells in regenerative medicine with particular emphasis on spinal cord repair, ligament and bone tissue engineering. · Biomimetic multiscale topography for cell alignment.
Author | : Giuseppe Perale |
Publisher | : Woodhead Publishing |
Total Pages | : 348 |
Release | : 2019-10-30 |
Genre | : Technology & Engineering |
ISBN | : 0081028083 |
Spinal Cord Injury (SCI) Repair Strategies provides researchers the latest information on potential regenerative approaches to spinal cord injury, specifically focusing on therapeutic approaches that target regeneration, including cell therapies, controlled drug delivery systems, and biomaterials. Dr. Giuseppe Perale and Dr. Filippo Rossi lead a team of authoritative authors in academia and industry in this innovative reference on the field of regenerative medicine and tissue engineering. This book presents all the information readers need to understand the current and potential array of techniques, materials, applications and their benefits for spinal cord repair. - Covers current and future repair strategies for spinal cord injury repair - Focuses on key research trends, clinics, biology and engineering - Provides fundamentals on regenerative engineering and tissue engineering
Author | : Vafa Rahimi-Movaghar |
Publisher | : Nova Science Publishers |
Total Pages | : 0 |
Release | : 2012 |
Genre | : Spinal cord |
ISBN | : 9781619428942 |
Spinal cord injury (SCI) is a devastating condition with enormous financial, social and personal costs. SCI is the most expensive traumatic condition in the United States. Overall, most frequent aetiologies of injury are motor vehicle crashes and falls, followed by violence, sports-related injuries, and work-related accidents. Research on SCI prevention, regeneration and long term care has progressed steadily over the past decade making an introductory foray into the epidemiology of SCI and important undertaking. This book is designed as a general reference book reviewing the epidemiology of SCI throughout the world with potential insight to cause and effect as well as the difficulties and boundaries to minimise this unfortunate occurrence.
Author | : |
Publisher | : |
Total Pages | : 23 |
Release | : 1986-01-01 |
Genre | : Kinesiology |
ISBN | : 9780912452647 |
Author | : World Health Organization |
Publisher | : World Health Organization |
Total Pages | : 250 |
Release | : 2013 |
Genre | : Medical |
ISBN | : 9241564660 |
"Every year between 250 000 and 500 000 people suffer a spinal cord injury, with road traffic crashes, falls and violence as the three leading causes. People with spinal cord injury are two to five times more likely to die prematurely. They also have lower rates of school enrollment and economic participation than people without such injuries. Spinal cord injury has costly consequences for the individual and society, but it is preventable, survivable and need not preclude good health and social inclusion. Ensuring an adequate medical and rehabilitation response, followed by supportive services and accessible environments, can help minimize the disruption to people with spinal cord injury and their families. The aims of International perspectives on spinal cord injury are to: ---assemble and summarize information on spinal cord injury, in particular the epidemiology, services, interventions and policies that are relevant, together with the lived experience of people with spinal cord injury; ---make recommendations for actions based on this evidence that are consistent with the aspirations for people with disabilities as expressed in the Convention on the Rights of Persons with Disabilities.
Author | : Ron El-Hawary |
Publisher | : Springer |
Total Pages | : 336 |
Release | : 2018-03-05 |
Genre | : Medical |
ISBN | : 3319715801 |
Comprised exclusively of clinical cases demonstrating the management of idiopathic, congenital, syndromic and neuromuscular early onset scoliosis (EOS), this concise, practical casebook will provide orthopedic surgeons with the best real-world strategies to properly manage the differing presentations of EOS they may encounter. Each chapter is a case that opens with a unique clinical presentation, followed by a description of the diagnosis, assessment and management techniques used to treat it, as well as the case outcome, clinical pearls and pitfalls, and literature review. Cases included illustrate different types and management strategies for EOS, including various spine-based growing rods, the vertical expandable prosthetic titanium rib (VEPTR), anterior vertebral body tethering (AVBT) and congenital resection. Treatment strategies for EOS with related conditions such as myelomeningocele, cerebral palsy and skeletal dysplasia are also discussed, as are common complications and the role of traction. Pragmatic and reader-friendly, Early Onset Scoliosis: A Clinical Casebook is an excellent resource for pediatric orthopedic surgeons and other physicians confronted with both common and complex disorders of the child’s spine.
Author | : Blaine S. Nashold |
Publisher | : Raven Press (ID) |
Total Pages | : 368 |
Release | : 1991 |
Genre | : Medical |
ISBN | : |
Author | : Charles H. Tator |
Publisher | : University of Toronto Press |
Total Pages | : 785 |
Release | : 2008-12-27 |
Genre | : Medical |
ISBN | : 1442691042 |
Catastrophic Injuries in Sport and Recreation is an essential reference guide to safe participation in a wide variety of sports and recreational activities. A masterful achievement of methodology, it is the first complete epidemiological study and analysis of all catastrophic injuries in all sports and recreational activities that occurred within a large defined geographical area with a large population: ten million people within the province of Ontario between 1986 and 1995. Concentrating on injuries that resulted in death or long term disability, the contributors identify both the personal risk factors for participants and the societal risk factors that are important causes for these kinds of injuries. Providing detailed analysis of 2154 case studies, the contributors demonstrate what went wrong in each event, and show how each injury could have been prevented. Recommending specific prevention strategies for a wide range of injuries, Catastrophic Injuries in Sport and Recreation is a practical medical reference for athletes and doctors alike.