The Health Effects of Cannabis and Cannabinoids

The Health Effects of Cannabis and Cannabinoids
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Total Pages: 487
Release: 2017-03-31
Genre: Science
ISBN: 0309453070
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Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.

Therapeutic Uses of Cannabis

Therapeutic Uses of Cannabis
Author: British Medical Association
Publisher: CRC Press
Total Pages: 164
Release: 1997-11-18
Genre: Medical
ISBN: 9789057023187
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At the last Annual Representative Meeting of the British Medical Association a motion was passed that `certain additional cannabinoids should be legalized for wider medicinal use.'' This report supports this landmark statement by reviewing the scientific evidence for the therapeutic use of cannabinoids and sets the agenda for change. It will be welcomed by those who believe that cannabinoids can be used in medical treatment. The report discusses in a clear and readable form the use and adverse effects of the drug for nausea, multiple sclerosis, pain, epilepsy, glaucoma, and asthma.

An Analysis of Marijuana Policy

An Analysis of Marijuana Policy
Author: National Research Council (U.S.). Committee on Substance Abuse and Habitual Behavior
Publisher: National Academies Press
Total Pages: 55
Release: 1982-01-01
Genre: Drug abuse
ISBN:
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Defenders of marijuana use may seize on the ambiguity or absence of evidence for such damage and ignore any other effects on education or safety; those opposed to marijuana use may emphasize the possibility of chronic disease that is suggested by some laboratory findings and ignore the social, political, and economic costs of fighting a well-established custom. The Committee wishes to make clear what it regards as the limits of this report for the selection of policy alteratives. Scientific judgment can estimate the prevalence of different kinds of use, risks to health, economic costs, and the like under current policies and can try to project such estimates for new policies. It can come to some conclusions based on those estimates. But selection of an alternative is always a value-governed choice, which can ultimately be made only by the political process.

Marijuana As Medicine?

Marijuana As Medicine?
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 216
Release: 2000-12-30
Genre: Medical
ISBN: 0309065313
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Some people suffer from chronic, debilitating disorders for which no conventional treatment brings relief. Can marijuana ease their symptoms? Would it be breaking the law to turn to marijuana as a medication? There are few sources of objective, scientifically sound advice for people in this situation. Most books about marijuana and medicine attempt to promote the views of advocates or opponents. To fill the gap between these extremes, authors Alison Mack and Janet Joy have extracted critical findings from a recent Institute of Medicine study on this important issue, interpreting them for a general audience. Marijuana As Medicine? provides patientsâ€"as well as the people who care for themâ€"with a foundation for making decisions about their own health care. This empowering volume examines several key points, including: Whether marijuana can relieve a variety of symptoms, including pain, muscle spasticity, nausea, and appetite loss. The dangers of smoking marijuana, as well as the effects of its active chemical components on the immune system and on psychological health. The potential use of marijuana-based medications on symptoms of AIDS, cancer, multiple sclerosis, and several other specific disorders, in comparison with existing treatments. Marijuana As Medicine? introduces readers to the active compounds in marijuana. These include the principal ingredient in Marinol, a legal medication. The authors also discuss the prospects for developing other drugs derived from marijuana's active ingredients. In addition to providing an up-to-date review of the science behind the medical marijuana debate, Mack and Joy also answer common questions about the legal status of marijuana, explaining the conflict between state and federal law regarding its medical use. Intended primarily as an aid to patients and caregivers, this book objectively presents critical information so that it can be used to make responsible health care decisions. Marijuana As Medicine? will also be a valuable resource for policymakers, health care providers, patient counselors, medical faculty and studentsâ€"in short, anyone who wants to learn more about this important issue.

Marijuana and Medicine

Marijuana and Medicine
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 288
Release: 1999-07-10
Genre: Medical
ISBN: 0309071550
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The medical use of marijuana is surrounded by a cloud of social, political, and religious controversy, which obscures the facts that should be considered in the debate. This book summarizes what we know about marijuana from evidence-based medicineâ€"the harm it may do and the relief it may bring to patients. The book helps the reader understand not only what science has to say about medical marijuana but also the logic behind the scientific conclusions. Marijuana and Medicine addresses the science base and the therapeutic effects of marijuana use for medical conditions such as glaucoma and multiple sclerosis. It covers marijuana's mechanism of action, acute and chronic effects on health and behavior, potential adverse effects, efficacy of different delivery systems, analysis of the data about marijuana as a gateway drug, and the prospects for developing cannabinoid drugs. The book evaluates how well marijuana meets accepted standards for medicine and considers the conclusions of other blue-ribbon panels. Full of useful facts, this volume will be important to anyone interested in informed debate about the medical use of marijuana: advocates and opponents as well as policymakers, regulators, and health care providers.

Marijuana

Marijuana
Author: Kevin P Hill
Publisher: Simon and Schuster
Total Pages: 146
Release: 2015-03-31
Genre: Self-Help
ISBN: 1616495707
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The leading clinical expert on marijuana sifts through the myths about the drug to deliver an unbiased, comprehensive guide backed by scientific facts to give you the information you need to make informed decisions about marijuana. Marijuana--or weed, pot, grass, MJ, Mary Jane, reefer, cannabis, or hemp among dozens of other names--has a long, colorful history dating back more than 2,000 years as the one of the most sought-after mood-altering substances in the world. Societal opinion about the drug has dramatically swayed over the years, from viewing it as a grave danger to society in the 1930s film Reefer Madness, to a harmless recreational high in the ’60s, to an addictive substance and gateway to such “hard” drugs as heroin today. The myths and misinformation about marijuana have only multiplied over the years as the controversy over legalization and medical marijuana grows. A nationally recognized clinical expert and leading researcher on marijuana, Kevin P. Hill provides a comprehensive guide to understanding the drug in Marijuana: The Unbiased Truth about the World’s Most Popular Weed. Through research-based historical, scientific, and medical information, Hill will help you sort through what you hear on the streets and in the media and cut straight to the facts. Whether you’re a parent concerned about your child’s use, someone with an illness considering medical marijuana as a treatment option, a user who has questions about its effect on your health, or if you’re just trying to make up your mind about legalization, this book will give you the most current and unbiased information you need to make informed decisions about marijuana.

Dying to Get High

Dying to Get High
Author: Wendy Chapkis
Publisher: NYU Press
Total Pages: 268
Release: 2008-08-03
Genre: Health & Fitness
ISBN: 0814716679
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Investigates one community of seriously ill patients fighting the federal government for the right to use physician-recommended marijuana. This book tackles the broader, complex history of medical marijuana in America. It asks what distinguishes a legitimate patient from an illegitimate "pothead," and "good" drugs from "bad".

Stoned

Stoned
Author: David Casarett M.D.
Publisher: Penguin
Total Pages: 306
Release: 2015-07-14
Genre: Health & Fitness
ISBN: 0698186648
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A doctor discovers the surprising truth about marijuana No substance on earth is as hotly debated as marijuana. Opponents claim it’s dangerous, addictive, carcinogenic, and a gateway to serious drug abuse. Fans claim it as a wonder drug, treating cancer, anorexia, AIDS, chronic pain, glaucoma, arthritis, migraines, PTSD, and insomnia. Patients suffering from these conditions need—and deserve—hard facts based on medical evidence, not hysteria and superstition. In Stoned, palliative care physician Dr. David Casarett sets out to do anything—including experimenting on himself—to find evidence of marijuana’s medical potential. He smears mysterious marijuana paste on his legs and samples pot wine. He poses as a patient at a seedy California clinic and takes lessons from an artisanal hash maker. In conversations with researchers, doctors, and patients around the world he learns how marijuana works—and doesn’t—in the real world. Dr. Casarett unearths tales of near-miraculous success, such as a child with chronic seizures who finally found relief in cannabidiol oil. In Tel Aviv, he learns of a nursing home that’s found success giving marijuana to dementia patients. On the other hand, one patient who believed marijuana cured her lung cancer has clearly been misled. As Casarett sifts the myth and misinformation from the scientific evidence, he explains, among other things: • Why marijuana might be the best treatment option for some types of pain • Why there’s no significant risk of lung damage from smoking pot • Why most marijuana-infused beer or wine won’t get you high Often humorous, occasionally heartbreaking, and full of counterintuitive conclusions, Stoned offers a compassionate and much-needed medical practitioner’s perspective on the potential of this misunderstood plant.

Cannabis Healing

Cannabis Healing
Author: Franjo Grotenhermen
Publisher: Simon and Schuster
Total Pages: 303
Release: 2020-09-22
Genre: Health & Fitness
ISBN: 1620558327
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Everything you need to know to use cannabinoids safely and effectively for better health and healing of a wide range of conditions • Explains the biochemistry of cannabinoids and shows how they interact with the human body • Offers a complete discussion of safe use, possible side effects, contraindications, and precautions, including during pregnancy and chemotherapy • Explores the use of CBD to treat seizures, anxiety, muscular disorders, and psychotic states and the use of THC to treat schizophrenia, Alzheimer’s, ADHD, Tourette’s, Parkinson’s, depression, COPD, and chronic pain, among many other physical, neurological, and emotional conditions In this authoritative yet practical guide to the healing properties of cannabis and cannabinoids such as THC and CBD, Franjo Grotenhermen, M.D., explores how to use these substances to treat a wide range of physical and emotional conditions. Dr. Grotenhermen first examines the history of marijuana as medicine, including its important role in U.S. medical practice during the 19th century. He explains the biochemistry of cannabinoids and shows how they interact with the human body, including a look at cannabinoid receptors and how cannabinoids occur naturally in the body. The author then draws on his years of experience legally treating patients in Germany as well as numerous research studies and tests to provide an in-depth guide to the many healing applications for cannabis and its derivatives. The therapeutic applications covered include the use of CBD to treat seizures, epilepsy, anxiety, several forms of cancer, muscular disorders, and psychotic states and the use of THC to treat schizophrenia, Alzheimer’s, ADHD, Tourette’s, Parkinson’s, impotence, depression, lupus, COPD, and chronic pain, among many other physical, neurological, and emotional conditions. The author examines the various cannabis-derived medications available, such as Cannabinol, Dronabinol, and Marinol, and the main methods of administering cannabis. He offers a complete discussion of safe use, possible side effects, contraindications, and precautions (including during pregnancy and chemotherapy), alongside research data that confirms cannabis as one of the least toxic substances in existence. Written by a practicing physician, this guide provides everything you need to know to use cannabinoids safely and effectively for health and healing.

Cannabis sativa L. - Botany and Biotechnology

Cannabis sativa L. - Botany and Biotechnology
Author: Suman Chandra
Publisher: Springer
Total Pages: 479
Release: 2017-05-23
Genre: Science
ISBN: 3319545647
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This book highlights current Cannabis research: its botany, authentication, biotechnology, in vitro propagation, chemistry, cannabinoids biosynthesis, metabolomics, genomics, biomass production, quality control, and pharmacology. Cannabis sativa L. (Family: Cannabaceae) is one of the oldest sources of fiber, food and medicine. This plant has been of interest to researchers, general public and media not only due to its medicinal properties but also the controversy surrounding its illicit use. Cannabis has a long history of medicinal use in the Middle East and Asia, being first introduced as a medicine in Western Europe in the early 19th century. Due to its numerous natural constituents, Cannabis is considered a chemically complex species. It contains a unique class of terpeno-phenolic compounds (cannabinoids or phytocannabinoids), which have been extensively studied since the discovery of the chemical structure of tetrah ydrocannabinol (Δ9-THC), commonly known as THC, the main constituent responsible for the plant’s psychoactive effects. An additionally important cannabinoid of current interest is Cannabidiol (CBD). There has been a significant interest in CBD and CBD oil (extract of CBD rich Cannabis) over the last few years because of its reported activity as an antiepileptic agent, particularly its potential use in the treatment of intractable epilepsy in children.