Management of Dysregulated Immune Response in the Critically Ill

Management of Dysregulated Immune Response in the Critically Ill
Author: Zsolt Molnar
Publisher: Springer Nature
Total Pages: 325
Release: 2023-03-11
Genre: Medical
ISBN: 3031175727

This book, part of the European Society of Intensive Care Medicine (ESICM) textbook series, deals with dysregulated host response a relatively new term introduced by the Sepsis-3 definitions in 2016. In contrast to systemic inflammatory response syndrome (SIRS) that has been used for nearly 30 years, this is a fundamentally new concept, which requires some sort of a paradigm shift in the way of thinking of critical care physicians. This change obviously requires time and after 5 years, time is ripe to summarize the knowledge in the form of a comprehensive book. The book is split in 4 sections. In the first one, the host immune response is explained in 11 chapters, followed by the next part, summarizing the possible tools for assessment at the bedside. The third and the fourth parts focus on the effects of dysregulated immune response on vital organ function and on the possible ways of immunomodulation. Written by internationally acclaimed experts of the field, the book is of value for all those intensivists and allied professionals working in ICUs.

Stress Challenges and Immunity in Space

Stress Challenges and Immunity in Space
Author: Alexander Choukèr
Publisher: Springer
Total Pages: 0
Release: 2020-12-03
Genre: Medical
ISBN: 9783030169985

This book explains how stress – either psychological or physical – can activate and/or paralyse human innate or adaptive immunity. Adequate immunity is crucial for maintaining health, both on Earth and in space. During space flight, human physiology is specifically challenged by complex environmental stressors, which are most pronounced during lunar or interplanetary missions. Adopting an interdisciplinary approach, the book identifies the impact of these stressors – the space exposome – on immunity as a result of (dys-)functions of specific cells, organs and organ networks. These conditions (e.g. gravitation changes, radiation, isolation/confinement) affect immunity, but at the same time provide insights that may help to prevent, diagnose and address immune-related health alterations. Written by experts from academia, space agencies and industry, the book is a valuable resource for professionals, researchers and students in the field of medicine, biology and technology. The chapters “The Impact of Everyday Stressors on the Immune System and Health”, “Stress and Radiation Responsiveness” and “Assessment of Radiosensitivity and Biomonitoring of Exposure to Space adiation” are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Post-Intensive Care Syndrome

Post-Intensive Care Syndrome
Author: Jean-Charles Preiser
Publisher: Springer Nature
Total Pages: 374
Release: 2019-08-31
Genre: Medical
ISBN: 3030242501

This book, part of the European Society of Intensive Care Medicine textbook series, provides detailed up-to-date information on the physical, cognitive, and psychological impairments that are frequently present following a stay in an intensive care unit and examines in depth the available preventive and therapeutic strategies, including adapted rehabilitation programs. Beyond acquainting readers with the multiple facets of post-intensive care syndrome (PICS), the book aims to promote the effective follow-up of patients, thereby enhancing their ability to work and their functional autonomy, and to identify risk factors for the development of PICS as a stimulus to beneficial organizational changes in intensive care departments. The background to the book is the realization by healthcare providers that the quality of life of patients who have required a stay in an intensive care unit can be severely impaired or even become unacceptable. All too often, the diverse sequelae are overlooked by specialists of other disciplines. Moreover, families and caregivers are also at high risk of post-traumatic stress disorder and depression. The European Society of Intensive Care Medicine has developed the Lessons from the ICU series with the vision of providing focused and state-of-the-art overviews of central topics in Intensive Care and optimal resources for clinicians working in Intensive Care. This book, written by renowned experts in the field, will facilitate the transmission of key knowledge with significant clinical and financial benefits.

Sepsis Management in Resource-limited Settings

Sepsis Management in Resource-limited Settings
Author: Arjen M. Dondorp
Publisher: Springer
Total Pages: 226
Release: 2019-02-08
Genre: Medical
ISBN: 3030031438

This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors – to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based on both current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion.

Immune Response in the Critically Ill

Immune Response in the Critically Ill
Author: John C. Marshall
Publisher: Springer Science & Business Media
Total Pages: 458
Release: 2002-01-21
Genre: Medical
ISBN: 9783540425892

This book brings together basic scientists or clinicians from a variety of different backgrounds - immunology, infectious diseases or critical care - who share a common interest in understanding the changes that occur in immune responses in sepsis. It provides an up-to-date and unrivalled synthesis of current research in this rapidly developing field.

Covid-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients

Covid-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients
Author: Nicola Vargas
Publisher: Springer Nature
Total Pages: 206
Release: 2020-08-25
Genre: Medical
ISBN: 3030556212

This book describes the issues and challenges that clinicians encountered in the management of older critically ill patients during the Covid-19 pandemic, and offers practical information on how to manage them. Older adults are more susceptible to complications such as acute respiratory distress syndrome (ARDS) as a result of viral pneumonia. In addition, they often have multiple comorbidities and are commonly frail, which means their various organs and systems, such as the respiratory system, have reduced functional reserves. As such, older adults are less able to react to acute stressors. During the current Covid-19 pandemic, older adult patients' mortality is increased. Further, the infection and death rates of elderly people in nursing homes and health care institutions are high. Management of older adults with Covid is complicated. The reduced availability of beds may limit their access to ICU. Moreover, the prognosis may be poor, and airway management and ventilation strategies have to take into account various clinical and physiological characteristics specific to older patients. This book is addressed to all allied professionals involved in the management of older critically ill patients and presents information collected and practical lessons learned from the clinical daily management of this population during the pandemic.

New Strategies for Treatment of Sepsis

New Strategies for Treatment of Sepsis
Author: Antonio Mirijello
Publisher: Mdpi AG
Total Pages: 146
Release: 2021-12-27
Genre: Medical
ISBN: 9783036524832

This book represents a collection of paper from different specialists involved in the management of septic patients, aimed to disseminate the knowledge in the field of sepsis, particularly to non-intensivists physicians.

The Washington Manual of Critical Care

The Washington Manual of Critical Care
Author: Marin Kollef
Publisher: Lippincott Williams & Wilkins
Total Pages: 989
Release: 2024-06-30
Genre: Medical
ISBN: 197521546X

Part of the popular Washington Manual® handbook series, The Washington Manual® of Critical Care provides concise, high-yield content that reflects today’s fast-changing advances in the field. Edited by Drs. Marin H. Kollef, Vladimir N. Despotovic, Bryan D. Kraft, Rachel K. McDonald, and Nguyet Nguyen, and written by teams of Washington University residents and faculty, the fourth edition focuses on the essential information you need to know, using a brief, bulleted format, along with numerous figures, tables, algorithms, and images throughout. In one convenient, portable resource, you’ll find complete coverage of bedside diagnosis and management of the most frequently encountered illnesses and problems seen in the ICU—all at your fingertips for quick review and reference.

Mechanisms of Vascular Disease

Mechanisms of Vascular Disease
Author: Robert Fitridge
Publisher: University of Adelaide Press
Total Pages: 589
Release: 2011
Genre: Medical
ISBN: 1922064009

New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Oxford Textbook of Critical Care

Oxford Textbook of Critical Care
Author: Webb
Publisher: Oxford University Press
Total Pages: 1961
Release: 2020-01-10
Genre: Medical
ISBN: 0198855435

Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summarise each topic in order to aid quick review and decision making. Edited and written by an international group of recognized experts from many disciplines, the second edition of the Oxford Textbook of Critical Careprovides an up-to-date reference that is relevant for intensive care units and emergency departments globally. This volume is the definitive text for all health care providers, including physicians, nurses, respiratory therapists, and other allied health professionals who take care of critically ill patients.