The Mouse in Biomedical Research
Author | : Henry L. Foster |
Publisher | : |
Total Pages | : 0 |
Release | : 1981 |
Genre | : Medicine, Experimental |
ISBN | : 9780122625015 |
Download Mammalian Models For Research On Aging full books in PDF, epub, and Kindle. Read online free Mammalian Models For Research On Aging ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Author | : Henry L. Foster |
Publisher | : |
Total Pages | : 0 |
Release | : 1981 |
Genre | : Medicine, Experimental |
ISBN | : 9780122625015 |
Author | : Institute of Laboratory Animal Resources (U.S.). Committee on Animal Models for Research on Aging |
Publisher | : National Academies |
Total Pages | : 4 |
Release | : 1981-01-01 |
Genre | : Family & Relationships |
ISBN | : 9780309030946 |
Author | : P. Michael Conn |
Publisher | : Elsevier |
Total Pages | : 1103 |
Release | : 2011-04-28 |
Genre | : Medical |
ISBN | : 0080460062 |
The Handbook of Models for Human Aging is designed as the only comprehensive work available that covers the diversity of aging models currently available. For each animal model, it presents key aspects of biology, nutrition, factors affecting life span, methods of age determination, use in research, and disadvantages/advantes of use. Chapters on comparative models take a broad sweep of age-related diseases, from Alzheimer's to joint disease, cataracts, cancer, and obesity. In addition, there is an historical overview and discussion of model availability, key methods, and ethical issues. - Utilizes a multidisciplinary approach - Shows tricks and approaches not available in primary publications - First volume of its kind to combine both methods of study for human aging and animal models - Over 200 illustrations
Author | : Hal Sternberg |
Publisher | : Springer Science & Business Media |
Total Pages | : 214 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 3642599168 |
This laboratory manual provides the researcher with a specific group of techniques, emphasising throughout hands-on information. A variety of protocols using molecular, cellular and physiological techniques are presented in detail and appropriate animal models have been selected for the study of ageing and ageing-related diseases. Non-invasive in vivo techniques are described for the study of Alzheimers dementia and cardiovascular diseases, while techniques for detection of oxidative processes are presented to explore the role of free radicals in causing cell damage and mutations as well as techniques to study apoptosis for its role in cell ageing. XXXXXXXXX Neuer Text This lab manual provides hands-on protocols using molecular, cellular, and physiological techniques and the appropriate animal models for the study of aging and aging-related diseases. Non-invasive in vivo techniques are described for the study of Alzheimers dementia and cardiovascular diseases. Techniques for detection of oxidative processes are presented to explore the role of free radicals in causing cell damage, as well as techniques to study apoptosis for its role in cell aging. A Springer Lab Manual
Author | : National Research Council |
Publisher | : National Academies Press |
Total Pages | : 348 |
Release | : 2000-12-21 |
Genre | : Nature |
ISBN | : 0309070864 |
Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
Author | : F. A. Lints |
Publisher | : S. Karger AG (Switzerland) |
Total Pages | : 304 |
Release | : 1985 |
Genre | : Medical |
ISBN | : |
Author | : National Research Council |
Publisher | : National Academies Press |
Total Pages | : 223 |
Release | : 2003-08-22 |
Genre | : Science |
ISBN | : 030916785X |
Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.
Author | : Edward J. Masoro |
Publisher | : Academic Press |
Total Pages | : 682 |
Release | : 2006 |
Genre | : Family & Relationships |
ISBN | : 0120883872 |
This volume is a collection of 21 papers comprising conceptual and technical issues, non-mammalian models and mammalian models and including issues such as aging of the female reproductive system and computer modelling in the study of aging.
Author | : National Research Council |
Publisher | : National Academies Press |
Total Pages | : 85 |
Release | : 1998-02-16 |
Genre | : Science |
ISBN | : 0309060354 |
Printbegrænsninger: Der kan printes 10 sider ad gangen og max. 40 sider pr. session.
Author | : Felipe Sierra |
Publisher | : Springer |
Total Pages | : 637 |
Release | : 2015-11-10 |
Genre | : Medical |
ISBN | : 3319232460 |
This book provides the first comprehensive overview of a new scientific discipline termed Geroscience. Geroscience examines the molecular and cellular mechanisms that might explain why aging is the main risk factor for most chronic diseases affecting the elderly population. Over the past few decades, researchers have made impressive progress in understanding the genetics, biology and physiology of aging. This book presents vital research that can help readers to better understand how aging is a critical malleable risk factor in most chronic diseases, which, in turn, could lead to interventions that can help increase a healthy lifespan, or ‘healthspan.’ The book begins with an analysis of the Geroscience hypothesis, as well as the epidemiological underpinnings that define aging as a candidate main risk factor for most chronic diseases. Next, each chapter focuses on one particular disease, or group of diseases, with an emphasis on how basic molecular and cellular biology might explain why aging is a major risk factor for it. Coverage in the book includes: cancer, cardiovascular disease, dementias, stroke, Parkinson's and Alzheimer’s diseases, osteoporosis, arthritis, diabetes asthma, emphysema, kidney disease, vision impairment, and AIDS/HIV. It finishes with a chapter on pain in the elderly and an overview of future steps needed to bring the newly acquired knowledge into the clinic and the public at large.