Lung Biology And Pathophysiology
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| Author | : Venkataramana K Sidhaye |
| Publisher | : Academic Press |
| Total Pages | : 277 |
| Release | : 2017-03-09 |
| Genre | : Medical |
| ISBN | : 0128038810 |
Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease provides a one-stop resource capturing developments in lung epithelial biology related to basic physiology, pathophysiology, and links to human disease. The book provides access to knowledge of molecular and cellular aspects of lung homeostasis and repair, including the molecular basis of lung epithelial intercellular communication and lung epithelial channels and transporters. Also included is coverage of lung epithelial biology as it relates to fluid balance, basic ion/fluid molecular processes, and human disease. Useful to physician and clinical scientists, the contents of this book compile the important and most current findings about the role of epithelial cells in lung disease. Medical and graduate students, postdoctoral and clinical fellows, as well as clinicians interested in the mechanistic basis for lung disease will benefit from the books examination of principles of lung epithelium functions in physiological condition. - Provides a single source of information on lung epithelial junctions and transporters - Discusses of the role of the epithelium in lung homeostasis and disease - Includes capsule summaries of main conclusions as well as highlights of future directions in the field - Covers the mechanistic basis for lung disease for a range of audiences
| Author | : Richard A. Parent |
| Publisher | : Academic Press |
| Total Pages | : 835 |
| Release | : 2015-03-13 |
| Genre | : Medical |
| ISBN | : 0124047262 |
Comparative Biology of the Normal Lung, Second Edition, offers a rigorous and comprehensive reference for all those involved in pulmonary research. This fully updated work is divided into sections on anatomy and morphology, physiology, biochemistry, and immunological response. It continues to provide a unique comparative perspective on the mammalian lung. This edition includes several new chapters and expanded content, including aging and development of the normal lung, mechanical properties of the lung, genetic polymorphisms, the comparative effect of stress of pulmonary immune function, oxygen signaling in the mammalian lung and much more. By addressing scientific advances and critical issues in lung research, this 2nd edition is a timely and valuable work on comparative data for the interpretation of studies of animal models as compared to the human lung. - Edited and authored by experts in the field to provide an excellent and timely review of cross-species comparisons that will help you interpret and compare data from animal studies to human findings - Incorporates lung anatomy and physiology, cell specific interactions and immunological responses to provide you with a single and unique multidisciplinary source on the comparative biology of the normal lung - Includes new and expanded content on neonatal and aged lungs, developmental processes, cell signaling, antioxidants, airway cells, safety pharmacology and much more - Section IV on Physical and Immunological Defenses has been significantly updated with 9 new chapters and an increased focus on the pulmonary immunological system
| Author | : United States. Public Health Service. Office of the Surgeon General |
| Publisher | : |
| Total Pages | : 728 |
| Release | : 2010 |
| Genre | : Government publications |
| ISBN | : |
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
| Author | : John Burnard West |
| Publisher | : Lippincott Williams & Wilkins |
| Total Pages | : 210 |
| Release | : 1998 |
| Genre | : Medical |
| ISBN | : 9780683302257 |
This companion monograph to West's Respiratory Physiology, which looks at normal respiratory function, focuses instead on the function of the diseased lung. The text offers a concise overview of the disease states of the lung, emphasizing structure and function. For the Sixth Edition, the basic science will be updated to reflect advances in pulmonary pathophysiology in the last five years, including pulmonary function tests, pathophysiology of asthma, pulmonary edema, pulmonary hypertension, air pollution by aerosols, oxygen therapy, and mechanical ventilation. A second interior color is also new to this edition. Intended for second-year medical students taking system-based pathophysiology courses, this book will also prove useful to students in clerkship/rotation.
| Author | : Allan I. Pack |
| Publisher | : CRC Press |
| Total Pages | : 735 |
| Release | : 2002-05-21 |
| Genre | : Medical |
| ISBN | : 0824744810 |
Considers the relationship between obstructive sleep apnea (OSA) and cardiovascular disease, right and left ventricular dysfunction, and hypertension. Sleep Apnea analyzes techniques to identify, diagnose, and monitor sleep-induced upper airway obstruction developments in functional brain imaging associated with sleep and
| Author | : Yutong Zhao |
| Publisher | : CRC Press |
| Total Pages | : 436 |
| Release | : 2024-02-20 |
| Genre | : Medical |
| ISBN | : 1003833284 |
The lungs are the organ for gas exchange between the body and the external environment. Dysfunction of upper airway epithelium and smooth muscle cells leads to pathogenesis of asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis, and other conditions, resulting in airway inflammation and narrowing. Injury to alveolar epithelium and endothelium causes influx of neutrophil and protein-rich fluid from circulation, resulting in edema and disruption of gas exchange. In addition to lung structural cells, immune cells, including alveolar macrophages and lymphocytes play critical roles in the maintenance of lung function. This book contributes to the understanding homeostasis of lung cells in the physiological and pathological conditions critical to the development of novel therapeutics. Key Features Highlights the role the lungs play as an interface between the body and the environment Describes the underlying mechanism of lung diseases Emphasizes the ways nutrition contributes to lung health as well as the ways pollution adversely affect lung function Includes contributions from leading researchers Chapters 8 and 13 of this book are available for free in PDF format as Open Access from the individual product page at www.routledge.com. It has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license.
| Author | : Hans Bisgaard |
| Publisher | : CRC Press |
| Total Pages | : 536 |
| Release | : 2001-10-02 |
| Genre | : Medical |
| ISBN | : 0824741978 |
This book focuses on the aerosol treatment of lung diseases, recent improvements in the understanding of proper dosage, and major innovations in device technology applied to clinical practice. Examines the behavior of inspired spherical particles in the respiratory tract!Featuring over 1300 references, drawings, tables, and photographs.
| Author | : Robert H. Notter |
| Publisher | : CRC Press |
| Total Pages | : 476 |
| Release | : 2000-07-18 |
| Genre | : Science |
| ISBN | : 9780824704018 |
Integrating basic and clinical research on the biophysical and physiological functions of pulmonary surfactants, this practical reference presents thorough, cutting-edge coverage on surfactant-related lung disease. Manage neonatal respiratory distress syndrome (RDS), acute respiratory distress syndrome (ARDS), and acute lung injury more effectively!
| Author | : Andrew M. Churg |
| Publisher | : Thieme |
| Total Pages | : 1234 |
| Release | : 2011-01-01 |
| Genre | : Medical |
| ISBN | : 1604064978 |
A cornerstone text in a new edition! Thurlbeck's cornerstone textbook and reference on pulmonary pathology returns in a brand new edition! Updated with the latest advances in the field, this book will help you: Save time with all-inclusive coverage of neoplastic, non-neoplastic, infectious, occupational/environmental, and developmental pathologies Learn how molecular biology provides a greater understanding of lung development Gain new insights into the diagnosis of neoplastic and non-neoplastic lung disease *Find pertinent information on clinical features, epidemiology, and pathogenetic mechanisms of lung disease Comprehensive in its scope and authoritative in its scholarship, Thurlbeck's Pathology of the Lung is a virtual one-volume encyclopedia written by a ''who's who'' of specialists. It is the one text that no pathologist, pulmonologist, or resident in either specialty can afford to be without.
| Author | : Donald J. Massaro |
| Publisher | : CRC Press |
| Total Pages | : 608 |
| Release | : 2004-09-09 |
| Genre | : Medical |
| ISBN | : 9780824754396 |
This reference compiles the most current technical and biological data available to survey the state-of-science in the care and management of patients with bronchopulmonary dysplasia, COPD, and other forms of lung disease-tracking the initiation and progression of processes that cause airway obstruction, the biologic and physiological abnormalities that characterize COPD, and the potential reversibility of the inflammatory response in COPD for improved patient diagnosis and treatment.
