Low Dose Combined Micropet Ct Imaging Of Mice
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Molecular Imaging I
Author | : Wolfhard Semmler |
Publisher | : Springer Science & Business Media |
Total Pages | : 298 |
Release | : 2008-07-15 |
Genre | : Medical |
ISBN | : 3540727183 |
The aim of this textbook of molecular imaging is to provide an up to date review of this rapidly growing field and to discuss basic methodological aspects necessary for the interpretation of experimental and clinical results. Emphasis is placed on the interplay of imaging technology and probe development, since the physical properties of the imaging approach need to be closely linked with the biologic application of the probe (i.e. nanoparticles and microbubbles). Various chemical strategies are discussed and related to the biologic applications. Reporter-gene imaging is being addressed not only in experimental protocols, but also first clinical applications are discussed. Finally, strategies of imaging to characterize apoptosis and angiogenesis are described and discussed in the context of possible clinical translation.
Small Animal Imaging
Author | : Fabian Kiessling |
Publisher | : Springer |
Total Pages | : 871 |
Release | : 2017-05-22 |
Genre | : Medical |
ISBN | : 3319422022 |
This textbook is a practical guide to the use of small animal imaging in preclinical research that will assist in the choice of imaging modality and contrast agent and in study design, experimental setup, and data evaluation. All established imaging modalities are discussed in detail, with the assistance of numerous informative illustrations. While the focus of the new edition remains on practical basics, it has been updated to encompass a variety of emerging imaging modalities, methods, and applications. Additional useful hints are also supplied on the installation of a small animal unit, study planning, animal handling, and cost-effective performance of small animal imaging. Cross-calibration methods and data postprocessing are considered in depth. This new edition of Small Animal Imaging will be an invaluable aid for researchers, students, and technicians involved in research into and applications of small animal imaging.
Image Reconstruction from Projections
Author | : Gabor T. Herman |
Publisher | : |
Total Pages | : 352 |
Release | : 1980 |
Genre | : Medical |
ISBN | : |
Image reconstruction from projections. Probability and random variables. An overview of the process of CT. Physical problems associated with data collection in CT. Computer simulation of data collection in CT. Data collection and reconstruction of the head phantom under various assumptions. Basic concepts of reconstruction algorithms. Backprojection. Convolution method for parallel beams. Other transform methods for parallel beams. Convolution methods for divergent beams. The algebraic reconstruction techniques. Quadratic optimization methods. Noniterative series expansion methods. Truly three-dimensional reconstruction. Three-dimensional display of organs. Mathematical background.
Molecular Imaging of Small Animals
Author | : Habib Zaidi |
Publisher | : Springer |
Total Pages | : 762 |
Release | : 2014-05-27 |
Genre | : Medical |
ISBN | : 1493908944 |
This book examines the fundamental concepts of multimodality small-animal molecular imaging technologies and their numerous applications in biomedical research. Driven primarily by the widespread availability of various small-animal models of human diseases replicating accurately biological and biochemical processes in vivo, this is a relatively new yet rapidly expanding field that has excellent potential to become a powerful tool in biomedical research and drug development. In addition to being a powerful clinical tool, a number of imaging modalities including but not limited to CT, MRI, SPECT and PET are also used in small laboratory animal research to visualize and track certain molecular processes associated with diseases such as cancer, heart disease and neurological disorders in living small animal models of disease. In vivo small-animal imaging is playing a pivotal role in the scientific research paradigm enabling to understand human molecular biology and pathophysiology using, for instance, genetically engineered mice with spontaneous diseases that closely mimic human diseases.
Geometric Modeling for Scientific Visualization
Author | : Guido Brunnett |
Publisher | : Springer Science & Business Media |
Total Pages | : 512 |
Release | : 2003-11-17 |
Genre | : Mathematics |
ISBN | : 9783540401162 |
Geometric Modeling and Scientific Visualization are both established disciplines, each with their own series of workshops, conferences and journals. But clearly both disciplines overlap; this observation led to the idea of composing a book on Geometric Modeling for Scientific Visualization.
Handbook of Models for Human Aging
Author | : P. Michael Conn |
Publisher | : Elsevier |
Total Pages | : 1103 |
Release | : 2011-04-28 |
Genre | : Medical |
ISBN | : 0080460062 |
The Handbook of Models for Human Aging is designed as the only comprehensive work available that covers the diversity of aging models currently available. For each animal model, it presents key aspects of biology, nutrition, factors affecting life span, methods of age determination, use in research, and disadvantages/advantes of use. Chapters on comparative models take a broad sweep of age-related diseases, from Alzheimer's to joint disease, cataracts, cancer, and obesity. In addition, there is an historical overview and discussion of model availability, key methods, and ethical issues. - Utilizes a multidisciplinary approach - Shows tricks and approaches not available in primary publications - First volume of its kind to combine both methods of study for human aging and animal models - Over 200 illustrations
Basic Science of PET Imaging
Author | : Magdy M. Khalil |
Publisher | : Springer |
Total Pages | : 621 |
Release | : 2016-11-07 |
Genre | : Medical |
ISBN | : 3319400703 |
This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceuticals, with information on labeling strategies, tracer quality control, and regulation of radiopharmaceutical production in Europe and the United States. PET physics and instrumentation are then discussed, covering the basic principles of PET and PET scanning systems, hybrid PET/CT and PET/MR imaging, system calibration, acceptance testing, and quality control. Subsequent sections focus on image reconstruction, processing, and quantitation in PET and hybrid PET and on imaging artifacts and correction techniques, with particular attention to partial volume correction and motion artifacts. The book closes by examining clinical applications of PET and hybrid PET and their physiological and/or molecular basis in conjunction with technical foundations in the disciplines of oncology, cardiology and neurology, PET in pediatric malignancy and its role in radiotherapy treatment planning. Basic Science of PET Imaging will meet the needs of nuclear medicine practitioners, other radiology specialists, and trainees in these fields.
Radiological Physics
Author | : M. E. J. Young |
Publisher | : |
Total Pages | : 624 |
Release | : 1967 |
Genre | : Medical radiology |
ISBN | : |
PET/CT Imaging
Author | : Kanhaiyalal Agrawal |
Publisher | : Springer Nature |
Total Pages | : 132 |
Release | : 2021-12-02 |
Genre | : Medical |
ISBN | : 3030754766 |
The aim of this book is to provide concise information and quick reference on the basics and practice of PET/CT for beginners. The chapters are written by Nuclear Medicine experts from different countries with enormous experience in PET/CT practice. Starting with the basics of PET/CT describing physics and the use of radiopharmaceuticals in PET/CT, the book explores the principle of PET/CT in radiotherapy planning. The last five chapters explore normal variation, pitfalls and artefacts commonly seen with various routinely used PET radiotracers. The text is enriched by tables and highlighted clinical cases for better understanding. This book will be of interest mostly to nuclear medicine physicians and radiologists, but it may be appealing also to a wider medical community including oncologists and radiotherapists.