Long Circulating Liposomes Old Drugs New Therapeutics
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Author | : Martin C. Woodle |
Publisher | : Springer Science & Business Media |
Total Pages | : 327 |
Release | : 2013-06-29 |
Genre | : Medical |
ISBN | : 3662221152 |
This book provides an up-to-date evaluation of clinical aspects of newly available "long-circulating liposome" formulations. Based on results from numerous clinical studies, the book describes the fundamentals of this new technology, discusses how it may influence the pharmacology of existing well-known agents reformulated in this manner, and elaborates on future expectations. It provides the practicing clinician - in particular, oncologists and critical care infectious disease physicians - with the tools needed to use these new formulations towards the best outcome for the patient.
Author | : Martin C. Woodle |
Publisher | : Springer |
Total Pages | : 301 |
Release | : 1997-12-16 |
Genre | : Medical |
ISBN | : 9783540630821 |
This book provides an up-to-date evaluation of clinical aspects of newly available "long-circulating liposome" formulations. Based on results from numerous clinical studies, the book describes the fundamentals of this new technology, discusses how it may influence the pharmacology of existing well-known agents reformulated in this manner, and elaborates on future expectations. It provides the practicing clinician - in particular, oncologists and critical care infectious disease physicians - with the tools needed to use these new formulations towards the best outcome for the patient.
Author | : Gregory Gregoriadis |
Publisher | : CRC Press |
Total Pages | : 462 |
Release | : 2006-09-12 |
Genre | : Medical |
ISBN | : 0849397286 |
Liposome Technology, Volume III: Interactions of Liposomes with the Biological Milieu, Third Edition, is a comprehensively updated and expanded new edition of a classic text in the field. Including step-by-step technical details, Volume III describes technologies for yielding liposomes that can function in a targeted fashion, and highlights methods
Author | : Yashwant Pathak |
Publisher | : CRC Press |
Total Pages | : 418 |
Release | : 2016-04-19 |
Genre | : Medical |
ISBN | : 1420078054 |
Exploring fundamental concepts, Drug Delivery Nanoparticles Formulation and Characterization presents key aspects of nanoparticulate system development for various therapeutic applications and provides advanced methods used to file for regulatory approval.This comprehensive guide features:Process Analytical Techniques (PAT) used in manufacturing Na
Author | : Vandana Patravale |
Publisher | : Elsevier |
Total Pages | : 244 |
Release | : 2012-10-31 |
Genre | : Technology & Engineering |
ISBN | : 1908818190 |
Nanotechnology-based therapeutics, operating at scales of billionths of a metre, have great potential for future expansion in altering the scale and methods of drug delivery. The availability of these novel formulations to once-inaccessible areas of the body has greatly expanded the therapeutic window of existing drug molecules. Nanoparticulate drug delivery highlights and examines the transition of nanoparticulate drug delivery systems from the laboratory into a commercially viable sector. The first chapters of the book provide an overview of the use and characterization of nanoparticulate systems as drug carriers, including the assessment of their morphology, sterility and potential toxicity. In the latter part of the book, chapters cover nanotoxicology, regulatory aspect and clinical trials, ending with an overview of several case studies and a look towards future developments. - Discusses the issues surrounding nanoparticulate products, based on personal experience of their formulation - Provides an overview of new application areas, including RNA interference - Outlines the pros and cons of nanoparticulate products, and discusses how these may influence their route into the commercial sector
Author | : D. Robert Lu |
Publisher | : Springer Science & Business Media |
Total Pages | : 621 |
Release | : 2004-02-25 |
Genre | : Medical |
ISBN | : 1592597459 |
An authoritative and up-to-date survey of the fundamental principles, and practice of drug delivery at the cellular level. On the principles side, the authors discuss the broad spectrum of cellular delivery, ranging from coverage of cell-mediated immunity, gene delivery, and protein targeting, to cellular drug transport, cellular drug permeability, and a variety of carrier system related to targeted drug delivery. On the practice side, the authors focus on technological developments in cellular drug delivery, including novel formulations for the delivery of DNA and antisense oligonucleotides ,as well as drug targeting with immunoglobulin formulations and antibody-mediated approaches.
Author | : Sergey Ilyin |
Publisher | : CRC Press |
Total Pages | : 117 |
Release | : 2007-08-27 |
Genre | : Medical |
ISBN | : 1000713415 |
Integrating various technologies with informational systems provides vast improvements to the overall research and development that occur in the biopharmaceutical industry. One of the first books to explore this area, Functional Informatics in Drug Discovery examines all aspects of technology integration and information flow in a biopharmaceutical
Author | : Monika Schäfer-Korting |
Publisher | : Springer Science & Business Media |
Total Pages | : 506 |
Release | : 2010-03-10 |
Genre | : Medical |
ISBN | : 3642004776 |
In the view of most experts pharmacology is on drugs, targets, and actions. In the context the drug as a rule is seen as an active pharmaceutical ingredient and not as a complex mixture of chemical entities of a well defined structure. Today, we are becoming more and more aware of the fact that delivery of the active compound to the target site is a key. The present volume gives a topical overview on various modern approaches to drug targeting covering today’s options for specific carrier systems allowing successful drug treatment at various sites of the body difficult to address and allowing to increase the benefit-risk-ratio to the optimum possible.
Author | : Shyam Mohapatra |
Publisher | : Elsevier |
Total Pages | : 684 |
Release | : 2018-10-05 |
Genre | : Science |
ISBN | : 0128140321 |
Characterization and Biology of Nanomaterials for Drug Delivery: Nanoscience and Nanotechnology in Drug Delivery describes the techniques successfully employed for the application of nanocarriers loaded with the antioxidant enzyme, catalase, and thus targeted to endothelial cells. Methods of nanocarrier synthesis, loading within various systems, and the characterization of nanocarriers for targeting activities are covered, as are their advantages, disadvantages and applications. Reflecting the interdisciplinary nature of the subject matter, this book includes contributions by experts from different fields, all with various backgrounds and expertise. It will appeal to researchers and students from different disciplines, such as materials science, technology and various biomedical fields. - Enables readers from different fields to access recent research and protocols across traditional boundaries - Focuses on protocols and techniques, as well as the knowledge base of the field, thus enabling those in R&D to learn about, and successfully deploy, cutting-edge techniques - Explores both current and emerging classes of nanomaterials, along with their fundamentals and applications
Author | : Michel Pagé |
Publisher | : Springer Science & Business Media |
Total Pages | : 773 |
Release | : 2002-04-01 |
Genre | : Medical |
ISBN | : 1592591671 |
This volume introduces the principles and techniques of tumor targeting and critically surveys their applications from laboratory to bedside. By concisely synthesizing the many technical details, the authors illuminate this innovative technique, ranging from the fundamentals of drug targeting and in vivo and in vitro experimentation, to such emerging therapeutic uses as radioimmunotherapy, radioimmunodetection, therapy with cytotoxic antibodies, immunotoxins, enzyme prodrug immunotherapy, and immunotherapeutics with fusion proteins.