How Tobacco Smoke Causes Disease

How Tobacco Smoke Causes Disease
Author: United States. Public Health Service. Office of the Surgeon General
Publisher:
Total Pages: 728
Release: 2010
Genre: Government publications
ISBN:

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Livestock's Long Shadow

Livestock's Long Shadow
Author: Henning Steinfeld
Publisher: Food & Agriculture Org.
Total Pages: 418
Release: 2006
Genre: Business & Economics
ISBN: 9789251055717

"The assessment builds on the work of the Livestock, Environment and Development (LEAD) Initiative"--Pref.

Venture Capital and the Finance of Innovation

Venture Capital and the Finance of Innovation
Author: Andrew Metrick
Publisher: John Wiley and Sons
Total Pages: 1153
Release: 2011-06-15
Genre: Business & Economics
ISBN: 1118137884

This useful guide walks venture capitalists through the principles of finance and the financial models that underlie venture capital decisions. It presents a new unified treatment of investment decision making and mark-to-market valuation. The discussions of risk-return and cost-of-capital calculations have been updated with the latest information. The most current industry data is included to demonstrate large changes in venture capital investments since 1999. The coverage of the real-options methodology has also been streamlined and includes new connections to venture capital valuation. In addition, venture capitalists will find revised information on the reality-check valuation model to allow for greater flexibility in growth assumptions.

Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy
Author: John A. Kellum
Publisher: Oxford University Press
Total Pages: 329
Release: 2016
Genre: Medical
ISBN: 019022553X

Continuous Renal Replacement Therapy provides concise, evidence-based, bedside guidance for the management of critically ill patients with acute renal failure, offering quick reference answers to clinicians' questions about treatments and situations encountered in daily practice.

Convex Optimization

Convex Optimization
Author: Stephen P. Boyd
Publisher: Cambridge University Press
Total Pages: 744
Release: 2004-03-08
Genre: Business & Economics
ISBN: 9780521833783

Convex optimization problems arise frequently in many different fields. This book provides a comprehensive introduction to the subject, and shows in detail how such problems can be solved numerically with great efficiency. The book begins with the basic elements of convex sets and functions, and then describes various classes of convex optimization problems. Duality and approximation techniques are then covered, as are statistical estimation techniques. Various geometrical problems are then presented, and there is detailed discussion of unconstrained and constrained minimization problems, and interior-point methods. The focus of the book is on recognizing convex optimization problems and then finding the most appropriate technique for solving them. It contains many worked examples and homework exercises and will appeal to students, researchers and practitioners in fields such as engineering, computer science, mathematics, statistics, finance and economics.