Liver in Systemic Diseases, An Issue of Clinics in Liver Disease

Liver in Systemic Diseases, An Issue of Clinics in Liver Disease
Author: Jorge Herrera
Publisher: Elsevier Health Sciences
Total Pages: 233
Release: 2019-05-28
Genre: Medical
ISBN: 0323678165

In consultation with Consulting Editor, Dr. Norman Gitlin, Dr. Jorge Herrera has put together a timely look at health and function of the liver in systemic diseases. The issue has all of the top experts in their field contributing conscise reviews of the following topics: The Liver in Celiac Disease; The Liver in Sickle Cell Disease; Hepatic Complications of Inflammatory Bowel Disease; The Liver in Circulatory Disturbances; Hepatobiliary Complications in Critically Ill Patients; Endocrine Diseases and the Liver; Rheumatologic Diseases and the Liver; Hepatic Manifestations of Cystic Fibrosis; Hepatic Complications of Total Parenteral Nutrition; Hepatic Manifestations of Lymphoproliferative Disorders; Liver Disease in HIV Infection; Sarcoidosis and the Liver; Liver Disease in Pregnancy; and Obstructive Sleep Apnea and the Liver.Readers will come away with the latest updates they need to improve outcomes in hepatology patients.

Chronic Hepatitis C Virus

Chronic Hepatitis C Virus
Author: Mitchell L. Shiffman
Publisher: Springer Science & Business Media
Total Pages: 333
Release: 2011-11-17
Genre: Medical
ISBN: 1461411920

Chronic Hepatitis C Virus: Lessons from the Past, Promise for the Future documents the monumental advances that have been made in our understanding of chronic HCV during the past decade. The first section reviews the natural history of chronic HCV, how this virus can affect other organs in addition to the liver, and whether treating chronic HCV alters the natural history of this disease. Section 2 reviews the advances that have been made in the treatment of chronic HCV during the past decade with interferon based therapy. Separate chapters on response guided therapy and how to manage the adverse events associated with these medications provide the physician with the concepts required to more effectively treat chronic HCV now and in the future. As the genetics of virologic response have recently been elucidated, a chapter is devoted to helping the clinician understand how genes that modulate disease processes and their treatment are identified and utilized in clinical care. Section 3 deals with the future of HCV treatment and specific inhibitors of HCV. Specific chapters explain how targets for drugs are identified and how drugs are then developed and tested; how mutations of HCV develop and how anti-viral agents will affect this process; the most up to date data regarding the treatment of chronic HCV with peginterferon, ribavirin and anti-viral agents; and the potential to treat chronic HCV with just oral anti-viral agents and without peginterferon and ribavirin in the future. The final section of this book covers issues related to liver transplantation in patients with chronic HCV. Separate chapters review the natural history of chronic HCV in liver transplant recipients and the impact of utilizing HCV positive donors. The volume concludes with chapters that cover the treatment of chronic HCV both prior to and after liver transplantation with potent anti-viral agents. Chronic Hepatitis C Virus: Lessons from the Past, Promise for the Future is a valuable resource for all physicians caring for patients with chronic HCV.

Diseases of the Abdomen and Pelvis 2018-2021

Diseases of the Abdomen and Pelvis 2018-2021
Author: Juerg Hodler
Publisher: Springer
Total Pages: 262
Release: 2018-03-20
Genre: Medical
ISBN: 3319750194

This open access book deals with imaging of the abdomen and pelvis, an area that has seen considerable advances over the past several years, driven by clinical as well as technological developments. The respective chapters, written by internationally respected experts in their fields, focus on imaging diagnosis and interventional therapies in abdominal and pelvic disease; they cover all relevant imaging modalities, including magnetic resonance imaging, computed tomography, and positron emission tomography. As such, the book offers a comprehensive review of the state of the art in imaging of the abdomen and pelvis. It will be of interest to general radiologists, radiology residents, interventional radiologists, and clinicians from other specialties who want to update their knowledge in this area.

Drug-Induced Liver Injury

Drug-Induced Liver Injury
Author:
Publisher: Academic Press
Total Pages: 290
Release: 2019-07-13
Genre: Medical
ISBN: 0128173173

Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series

Cholestatic Liver Diseases, An Issue of Clinics in Liver Disease

Cholestatic Liver Diseases, An Issue of Clinics in Liver Disease
Author: Cynthia Levy
Publisher: Elsevier Health Sciences
Total Pages: 244
Release: 2013-05-28
Genre: Medical
ISBN: 1455771996

Dr. Levy is a key leader in the field of hepatology , and she has enlisted authors who are top experts in their fields to submit state-of-the-art clinical reviews on cholestatic liver diseases. Articles are devoted to genetic determinants of cholestasis, nuclear receptors as drug targets, drug-induced cholestasis, primary sclerosing cholangitis, therapeutic advances in primary biliary cirrhosis, overlap syndromes, autoimmune sclerosing cholangitis, secondary sclerosing cholangitis, Focus is also on familial cholestasis, allagile syndrome and other hereditary causes of cholestasis, Systemic causes of cholestasis, advances in pathogenesis and treatment of pruritus, care of the cholestatic patient, and transplantation for cholestatic diseases . Readers will come away with a full overview of the diagnosis and treatment of cholestatic liver diseases.

Pathology of the Liver

Pathology of the Liver
Author: Roderick N. M. MacSween
Publisher:
Total Pages: 982
Release: 2002
Genre: Medical
ISBN: 9780443061813

Here is the new edition of the definitive reference work on liver pathology. Comprehensive, authoritative and superbly illustrated, this book leads the field, with editors and contributors who represent a "who's who" of hepatopathology. The fourth edition is an invaluable bench-side reference and research tool for the day-to-day diagnosis of the wide range of appearances of the liver resulting from infection, tumours and tumour-like lesions or damage caused by drugs or toxins

Hepatic Critical Care

Hepatic Critical Care
Author: Rahul Nanchal
Publisher: Springer
Total Pages: 312
Release: 2018-01-08
Genre: Medical
ISBN: 3319664328

This book focuses on the critical care of the patient with acute, acute on chronic and chronic liver failure as well as the peri-operative care of the patient with liver transplantation. Each of these disease processes is unique in pathophysiological manifestations, underpinnings of physiology and treatment options. Patients with acute, chronic or acute on chronic liver failure are a growing fraction of ICU admissions. Hepatic Critical Care serves as the essential reference for both practicing intensivists at community hospitals and tertiary referral centers. This textbook is also targeted towards trainees specifically interested in taking care of patients with liver disease and liver transplantation.

Hepatotoxicity

Hepatotoxicity
Author: Hyman J. Zimmerman
Publisher: Lippincott Williams & Wilkins
Total Pages: 850
Release: 1999
Genre: Medical
ISBN: 9780781719520

Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

Stellate Cells in Health and Disease

Stellate Cells in Health and Disease
Author: Chandrashekhar Gandhi
Publisher: Academic Press
Total Pages: 335
Release: 2015-04-10
Genre: Science
ISBN: 0128005440

Stellate Cells in Health and Disease is a comprehensive reference providing the most up-to-date knowledge and perspectives on the function of stellate cells affecting the liver and other organs. The text presents comprehensive coverage of their already established role in hepatic fibrosis along with the newer emerging evidence for stellate cell participation in the liver cell (hepatocyte) survival and regeneration, hepatic immunobiology, transplant tolerance, and liver cancer. Chapters describe both animal and human research and the relevance of findings from animal research to human pathophysiology, and also contain sections on future directions which will be of special interest to basic and clinical researchers working on liver fibrosis, hepatic biology, and pathobiology. - Presents coverage of the mechanisms of liver fibrosis with stellate cells as a target for therapy. - Shows stellate cells as a major participant in hepatic immunobiology, including transplantation immunology. - Key illustrations show the phenotypical changes in stellate cells in situ and tissue culture, their interactions with other cell types, signaling pathways and demonstrate the functions and roles of stellate cell in pathological processes.

Pediatric Liver Disease, An Issue of Clinics in Liver Disease, E-Book

Pediatric Liver Disease, An Issue of Clinics in Liver Disease, E-Book
Author: Philip Rosenthal
Publisher: Elsevier Health Sciences
Total Pages: 233
Release: 2022-08-11
Genre: Medical
ISBN: 032389755X

In this issue, guest editors bring their considerable expertise to this important topic.Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.