Limb Development And Regeneration
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| Author | : Mary Ann Asson-Batres |
| Publisher | : Springer Nature |
| Total Pages | : 232 |
| Release | : 2020-04-15 |
| Genre | : Medical |
| ISBN | : 3030422828 |
This book covers subjects that have major impacts on society, such as the mechanism of maternal-fetal transfer of vitamin A, and the effects of alcohol on retinoic acid signaling and mammalian embryonic development. There has been an awareness of the importance of consuming vitamins throughout human history, but empirical studies of their physiological role and mode of action only began about 150 years ago. Since then, the biochemical nature of vitamin A and its active derivative, retinoic acid, have been identified and researchers around the globe have investigated retinoic acid’s physiological function in growth processes and in maintaining life Written by leading experts, this book discusses the latest findings and advances in retinoic acid research. It addresses topics such as the role of retinoic acid signaling in a multitude of processes, including limb, heart and respiratory system development, as well as its role in maintaining postnatal organ systems. This book is a valuable resource for scientists involved in vitamin A/retinoic acid research and readers interested in developmental biology.
| Author | : Hugh Wallace |
| Publisher | : John Wiley & Sons |
| Total Pages | : 296 |
| Release | : 1981 |
| Genre | : Science |
| ISBN | : |
| Author | : Lewis Wolpert |
| Publisher | : Oxford University Press |
| Total Pages | : 153 |
| Release | : 2011-08-25 |
| Genre | : Science |
| ISBN | : 0199601194 |
"A concise account of what we know about development discusses the first vital steps of growth and explores one of the liveliest areas of scientific research."--P. [2] of cover.
| Author | : David L. Stocum |
| Publisher | : Academic Press |
| Total Pages | : 474 |
| Release | : 2012-06-07 |
| Genre | : Technology & Engineering |
| ISBN | : 012384861X |
Regenerative Biology and Medicine, Second Edition — Winner of a 2013 Highly Commended BMA Medical Book Award for Medicine — discusses the fundamentals of regenerative biology and medicine. It provides a comprehensive overview, which integrates old and new data into an ever-clearer global picture. The book is organized into three parts. Part I discusses the mechanisms and the basic biology of regeneration, while Part II deals with the strategies of regenerative medicine developed for restoring tissue, organ, and appendage structures. Part III reflects on the achievements of regenerative biology and medicine; future challenges; bioethical issues that need to be addressed; and the most promising developments in regenerative medicine. The book is designed for multiple audiences: undergraduate students, graduate students, medical students and postdoctoral fellows, and research investigators interested in an overall synthesis of this field. It will also appeal to investigators from fields not directly related to regenerative biology and medicine, such as chemistry, informatics, computer science, mathematics, physics, and engineering. - Highly Commended 2013 BMA Medical Book Award for Medicine - Includes coverage of skin, hair, teeth, cornea, and central neural tissues - Provides description of regenetive medicine in digestive, respiratory, urogenital, musculoskeletal, and cardiovascular systems - Includes amphibians as powerful research models with discussion of appendage regeneration in amphibians and mammals
| Author | : Brian K. Hall |
| Publisher | : Academic Press |
| Total Pages | : 911 |
| Release | : 2014-12-23 |
| Genre | : Science |
| ISBN | : 0124166857 |
Bones and Cartilage provides the most in-depth review and synthesis assembled on the topic, across all vertebrates. It examines the function, development and evolution of bone and cartilage as tissues, organs and skeletal systems. It describes how bone and cartilage develop in embryos and are maintained in adults, how bone is repaired when we break a leg, or regenerates when a newt grows a new limb, or a lizard a new tail. The second edition of Bones and Cartilage includes the most recent knowledge of molecular, cellular, developmental and evolutionary processes, which are integrated to outline a unified discipline of developmental and evolutionary skeletal biology. Additionally, coverage includes how the molecular and cellular aspects of bones and cartilage differ in different skeletal systems and across species, along with the latest studies and hypotheses of relationships between skeletal cells and the most recent information on coupling between osteocytes and osteoclasts All chapters have been revised and updated to include the latest research. - Offers complete coverage of every aspect of bone and cartilage, with updated references and extensive illustrations - Integrates development and evolution of the skeleton, as well a synthesis of differentiation, growth and patterning - Treats all levels from molecular to clinical, embryos to evolution, and covers all vertebrates as well as invertebrate cartilages - Includes new chapters on evolutionary skeletal biology that highlight normal variation and variability, and variation outside the norm (neomorphs, atavisms) - Updates hypotheses on the origination of cartilage using new phylogenetic, cellular and genetic data - Covers stem cells in embryos and adults, including mesenchymal stem cells and their use in genetic engineering of cartilage, and the concept of the stem cell niche
| Author | : Brian K. Hall |
| Publisher | : University of Chicago Press |
| Total Pages | : 461 |
| Release | : 2008-09-15 |
| Genre | : Science |
| ISBN | : 0226313409 |
Long ago, fish fins evolved into the limbs of land vertebrates and tetrapods. During this transition, some elements of the fin were carried over while new features developed. Lizard limbs, bird wings, and human arms and legs are therefore all evolutionary modifications of the original tetrapod limb. A comprehensive look at the current state of research on fin and limb evolution and development, this volume addresses a wide range of subjects—including growth, structure, maintenance, function, and regeneration. Divided into sections on evolution, development, and transformations, the book begins with a historical introduction to the study of fins and limbs and goes on to consider the evolution of limbs into wings as well as adaptations associated with specialized modes of life, such as digging and burrowing. Fins into Limbs also discusses occasions when evolution appears to have been reversed—in whales, for example, whose front limbs became flippers when they reverted to the water—as well as situations in which limbs are lost, such as in snakes. With contributions from world-renowned researchers, Fins into Limbs will be a font for further investigations in the changing field of evolutionary developmental biology.
| Author | : J. Gordon Betts |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2013-04-25 |
| Genre | : |
| ISBN | : 9781947172807 |
| Author | : Heinz Redl |
| Publisher | : Springer |
| Total Pages | : 0 |
| Release | : 2017-02-16 |
| Genre | : Technology & Engineering |
| ISBN | : 9783319088303 |
This reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. There is particular emphasis on current understanding of tissue regeneration based on embryology and evolution studies, including mechanisms of amphibian regeneration. The book covers the use of autologous versus allogeneic cell sources, as well as various procedures used for cell isolation and cell pre-conditioning , such as cell sorting, biochemical and biophysical pre-conditioning, transfection and aggregation. It also presents cell modulation using growth factors, molecular factors, epigenetic approaches, changes in biophysical environment, cellular co-culture and other elements of the cellular microenvironment. The pathways of cell delivery are discussed with respect to specific clinical situations, including delivery of ex vivo manipulated cells via local and systemic routes, as well as activation and migration of endogenous reservoirs of reparative cells. The volume concludes with an in-depth discussion of the tracking of cells in vivo and their various regenerative activities inside the body, including differentiation, new tissue formation and actions on other cells by direct cell-to-cell communication and by secretion of biomolecules.
| Author | : Renato Paro |
| Publisher | : Springer Nature |
| Total Pages | : 215 |
| Release | : 2021-03-23 |
| Genre | : Science |
| ISBN | : 3030686701 |
This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease
| Author | : Pieter D. Nieuwkoop |
| Publisher | : Garland Science |
| Total Pages | : 252 |
| Release | : 1994 |
| Genre | : Medical |
| ISBN | : 9780815318965 |
A Systematical and Chronological Survey of the Development from the Fertilized Egg till the End of Metomorphosis
