Measuring Health

Measuring Health
Author: Ian McDowell
Publisher: Oxford University Press
Total Pages: 765
Release: 2006-03-09
Genre: Medical
ISBN: 0199725306

Worldwide economic constraints on health care systems have highlighted the importance of evidence-based medicine and evidence-based health policy. The resulting clinical trials and health services research studies require instruments to monitor the outcomes of care and the output of the health system. However, the over-abundance of competing measurement scales can make choosing a measure difficult at best. Measuring Health provides in-depth reviews of over 100 of the leading health measurement tools and serves as a guide for choosing among them.LNow in its third edition, this book provides a critical overview of the field of health measurement, with a technical introduction and discussion of the history and future directions for the field. This latest edition updates the information on each of the measures previously reviewed, and includes a complete new chapter on anxiety measurement to accompany the one on depression. It has also added new instruments to those previously reviewed in each of the chapters in the book.LChapters cover measurements of physical disability, social health, psychological well-being, anxiety, depression, mental status testing, pain, general health status and quality of life. Each chapter presents a tabular comparison of the quality of the instruments reviewed, followed by a detailed description of each method, covering its purpose and conceptual basis, its reliability and validity and, where possible, shows a copy of the actual scale. To ensure accuracy of the information, each review has been approved by the original author of each instrument or by an acknowledged expert.

Multiple Myeloma

Multiple Myeloma
Author: Thomas Moehler
Publisher: Springer Science & Business Media
Total Pages: 349
Release: 2011-04-21
Genre: Medical
ISBN: 3540857729

Multiple myeloma is currently still an incurable disease, but during the past decade knowledge of its molecular pathogenesis has increased rapidly. This has led to remarkable progress in both diagnosis and therapy, including in particular the approval of novel and first-in-class drugs such as thalidomide, bortezomib, and lenalidomide. This book, written by internationally acknowledged experts, covers a wide range of topics relating to multiple myeloma, including history, epidemiology, pathophysiology, clinical features, staging, and prognostic systems. The principal focus, however, is on therapy, with detailed information on the various promising treatment options which give hope that this cancer will be transformed into a chronic disease or even become curable. Individualized therapy and the variety of supportive treatment options, as described in this volume, will help in achieving this goal, as well as in reducing adverse events and improving quality of life.

Gulf War and Health

Gulf War and Health
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 617
Release: 2003-12-10
Genre: Medical
ISBN: 0309168414

Gulf War and Health, Volume 2, is the second in a series of congressionally-mandated studies by the Institute of Medicine that provides a comprehensive assessment of the available scientific literature on potential health effects of exposure to certain biological, chemical, and environmental agents associated with the Gulf War. In this second study, the committee evaluated the published, peer-reviewed literature on exposure to insecticides and solvents thought to have been present during the 1990-1991 war. Because little information exists on actual exposure levels â€" a critical factor when assessing health effects â€" the committee could not draw specific conclusions about the health problems of Gulf War veterans. However, the study found some evidence, although usually limited, to link specific long-term health outcomes with exposure to certain insecticides and solvents. The next phase of the series will examine the literature on potential health effects associated with exposure to selected environmental pollutants and particulates, such as oil-well fires and jet fuels.

NCI Fact Book

NCI Fact Book
Author: National Cancer Institute (U.S.)
Publisher:
Total Pages: 82
Release: 1979
Genre: Cancer
ISBN:

Cancer-Causing Viruses and Their Inhibitors

Cancer-Causing Viruses and Their Inhibitors
Author: Satya Prakash Gupta
Publisher: CRC Press
Total Pages: 502
Release: 2014-05-16
Genre: Medical
ISBN: 1466589787

Cancer-causing viruses, also called oncoviruses, play a key role in the development of certain cancers. They contribute to genetic changes that disrupt the cell cycle machinery, interfering with functions such as cell growth. Cancer-Causing Viruses and Their Inhibitors presents a plethora of research from internationally reputed contributors who di

Paediatric Haematology and Oncology

Paediatric Haematology and Oncology
Author: Simon Bailey
Publisher: Oxford University Press, USA
Total Pages: 624
Release: 2010
Genre: Medical
ISBN: 0199299676

While survival rates for children with cancer have increased in recent times, the increased use of more aggressive therapies has brought with it significant adverse effects. Therefore, the aim of pediatric oncologists has become to achieve "cure at least cost" by the appropriate reduction of the intensity and/or duration of treatment in carefully identified good prognosis patients. By comprehensively covering these issues, this handbook aims to provide residents in pediatric hematology and oncology, as well as staff in related medical or other healthcare disciplines, with an easily accessible source of information about the basic principles of childhood cancer and leukemia, as well as much of the more detailed specialist knowledge required to care for children with these conditions. Divided into sections to allow quick access to the necessary information, the handbook covers general principles of diagnosis and treatment, short and long term care, and oncological emergencies before moving on to chapters on specific disease. Normal values and useful websites are also included for reference.

Veterans and Agent Orange

Veterans and Agent Orange
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Total Pages: 739
Release: 2019-01-20
Genre: Medical
ISBN: 0309477166

From 1962 to 1971, the U.S. military sprayed herbicides over Vietnam to strip the thick jungle canopy that could conceal opposition forces, to destroy crops that those forces might depend on, and to clear tall grasses and bushes from the perimeters of US base camps and outlying fire-support bases. Mixtures of 2,4-dichlorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), picloram, and cacodylic acid made up the bulk of the herbicides sprayed. The main chemical mixture sprayed was Agent Orange, a 50:50 mixture of 2,4-D and 2,4,5-T. At the time of the spraying, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the most toxic form of dioxin, was an unintended contaminant generated during the production of 2,4,5-T and so was present in Agent Orange and some other formulations sprayed in Vietnam. Because of complaints from returning Vietnam veterans about their own health and that of their children combined with emerging toxicologic evidence of adverse effects of phenoxy herbicides and TCDD, the National Academies of Sciences, Engineering, and Medicine was asked to perform a comprehensive evaluation of scientific and medical information regarding the health effects of exposure to Agent Orange, other herbicides used in Vietnam, and the various components of those herbicides, including TCDD. Updated evaluations were conducted every two years to review newly available literature and draw conclusions from the overall evidence. Veterans and Agent Orange: Update 11 (2018) examines peer-reviewed scientific reports concerning associations between various health outcomes and exposure to TCDD and other chemicals in the herbicides used in Vietnam that were published between September 30, 2014, and December 31, 2017, and integrates this information with the previously established evidence database.

Cancer Genomics

Cancer Genomics
Author: Robert L. Strausberg
Publisher: IOS Press
Total Pages: 92
Release: 2002
Genre: Medical
ISBN: 9781586032517

This work states that we are no longer satisfied to study a gene or gene product in isolation, but rather we strive to view each gene within the complex circuitry of a cell. It states that as a family of diseases, all cancer results from changes in the genome.

Patty's Toxicology, 6 Volume Set

Patty's Toxicology, 6 Volume Set
Author: Eula Bingham
Publisher: John Wiley & Sons
Total Pages: 5872
Release: 2012-07-31
Genre: Science
ISBN: 0470410817

Featuring the improved format used in the 5th edition, this updated set presents, in logical groupings, comprehensive toxicological data for industrial compounds, including CAS numbers, physical and chemical properties, exposure limits, and biological tolerance values for occupational exposures, making it essential for toxicologists and industrial hygienists. This edition has about 40% new authors who have brought a new and international perspective to interpreting industrial toxicology, and discusses new subjects such as nanotechnology, flavorings and the food industry, reactive chemical control to comprehensive chemical policy, metalworking fluids, and pharmaceuticals.