Kinetics And 1 13c Isotope Effects Of Pyruvate Decarboxylase On Various Substrates
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Thiamine
| Author | : Frank Jordan |
| Publisher | : CRC Press |
| Total Pages | : 632 |
| Release | : 2003-12-11 |
| Genre | : Medical |
| ISBN | : 0824758714 |
Thiamine: Catalytic Mechanisms in Normal and Disease States brings together the most recent developments in thiamine diphosphate (TDP)-requiring enzyme research and details the mechanisms of catalysis and structure-function relationships, as well as pathophysiological aspects of a spectrum of diseases associated with TDP-requiring enzymes. Providing new insights into neurogenerative diseases, this volume associates defects in the function of TDP-dependent enzymes with numerous metabolic disorders and disease states and offers novel aspects of thiamine enzymes in chiral synthesis as well as new perspectives on the cellular role of thiamine triphosphate and thiamine triphosphates.
Synthesis and Applications of Isotopically Labelled Compounds 1997
| Author | : J. R. Heys |
| Publisher | : |
| Total Pages | : 776 |
| Release | : 1998-06-11 |
| Genre | : Reference |
| ISBN | : |
Synthesis and Applications of Isotopically Labelled Compounds provides a wide-ranging, authoritative and comprehensive coverage of the most recent advances in the synthesis, production and applications of stable and radioactive isotopes. This volume focuses on significant growth areas including applications of isotopes in clinical research and medicine, advances in the analysis of isotopically labelled compounds, novel approaches to compounds labelled with isotopes of hydrogen, applications of isotopes in organic and bio-organic reaction mechanisms, isotopes in macro-molecules, applications of isotopes in metabolism and toxicology, production of stable isotopes and radioisotopes and applications of isotopes in pharmaceutical and agricultural research. Contributions are drawn from major research groups around the world providing an invaluable information and reference source to anyone involved in the production of isotopes, the synthesis and analysis of stable or radioactive isotopically labelled compounds, the applications of short-lived isotopes, drug metabolism and pharmacokinetics, pharmaceutical research and development, clinical research, biosynthesis, handling radioisotopes, laboratory design and other related areas.
Stable Isotopes
| Author | : E. Roseland Klein |
| Publisher | : |
| Total Pages | : 680 |
| Release | : 1979 |
| Genre | : Science |
| ISBN | : 9780124136502 |
Index Medicus
| Author | : |
| Publisher | : |
| Total Pages | : 1780 |
| Release | : 2002 |
| Genre | : Medicine |
| ISBN | : |
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
The Enzyme Reference
| Author | : Daniel L. Purich |
| Publisher | : Elsevier |
| Total Pages | : 940 |
| Release | : 2003-01-04 |
| Genre | : Science |
| ISBN | : 0080550819 |
The aim of this work is to provide a fuller spectrum of information in a single source on enzyme-catalyzed reactions than is currently available in any published reference work or as part of any Internet database. The Enzyme Reference: A Comprehensive Guidebook to Enzyme Nomenclature, Reactions, and Methods includes 20,000 review articles and seminal research papers. Additionally, it provides a novel treatment of so-called ATPase and GTPase reactions to account for the noncovalent substratelike and productlike states of molecular motors, elongation factors, transporters, DNA helicases, G-reulatory proteins, and other energases. - Includes a compendium of over 6,000 enzyme reactions (including enzyme commission numbers, alternative names, substrates, products, alternative substrates, and properties) - Covers over 900 chemical structures of key metabolites and cofactors - Index directs readers to the exact pages for over 9,500 enzyme names
Methodologies for Metabolomics
| Author | : Norbert W. Lutz |
| Publisher | : Cambridge University Press |
| Total Pages | : 641 |
| Release | : 2013-01-21 |
| Genre | : Medical |
| ISBN | : 0521765900 |
Metabolomics, the global characterisation of the small molecule complement involved in metabolism, has evolved into a powerful suite of approaches for understanding the global physiological and pathological processes occurring in biological organisms. The diversity of metabolites, the wide range of metabolic pathways and their divergent biological contexts require a range of methodological strategies and techniques. Methodologies for Metabolomics provides a comprehensive description of the newest methodological approaches in metabolomic research. The most important technologies used to identify and quantify metabolites, including nuclear magnetic resonance and mass spectrometry, are highlighted. The integration of these techniques with classical biological methods is also addressed. Furthermore, the book presents statistical and chemometric methods for evaluation of the resultant data. The broad spectrum of topics includes a vast variety of organisms, samples and diseases, ranging from in vivo metabolomics in humans and animals to in vitro analysis of tissue samples, cultured cells and biofluids.
